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Rapid review for the anti-coronavirus effect of remdesivir.
Drug Discov Ther. 2020; 14(2):73-76.DD

Abstract

The outbreak of SARS-CoV-2 rapidly spread across China and worldwide. Remdesivir had been proposed as a promising option for treating coronavirus disease 2019 (COVID-19). We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. Even though remdesivir was proposed as a promising option for treating COVID-19 based on laboratory experiments and reports from compassionate use, its safety and effect in humans requires high-quality evidence from well-designed and adequately-powered clinical trials for further clarification.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Li Z
Centre of Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Wang X
Centre of Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Cao D
Hospital Laboratory, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Sun R
Department of Pulmonary and Critical Care Medicine, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Li C
Guangdong Traditional Medical and Sports Injury Rehabilitation Research Institute, Guangdong Second Provincial General Hospital, Guangzhou, China.
Li G
Centre of Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China. Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.

MeSH

Adenosine MonophosphateAlanineAnimalsAntiviral AgentsBetacoronavirusCOVID-19Clinical Trials as TopicCoronavirus InfectionsDrug Evaluation, PreclinicalHumansMiddle East Respiratory Syndrome CoronavirusPandemicsPneumonia, ViralSevere acute respiratory syndrome-related coronavirusSARS-CoV-2COVID-19 Drug Treatment

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32378648

Clinical Trial Links

Remdesivir in COVID-19 Lahore General Hospital

Citation

Li, Ziyi, et al. "Rapid Review for the Anti-coronavirus Effect of Remdesivir." Drug Discoveries & Therapeutics, vol. 14, no. 2, 2020, pp. 73-76.
Li Z, Wang X, Cao D, et al. Rapid review for the anti-coronavirus effect of remdesivir. Drug Discov Ther. 2020;14(2):73-76.
Li, Z., Wang, X., Cao, D., Sun, R., Li, C., & Li, G. (2020). Rapid review for the anti-coronavirus effect of remdesivir. Drug Discoveries & Therapeutics, 14(2), 73-76. https://doi.org/10.5582/ddt.2020.01015
Li Z, et al. Rapid Review for the Anti-coronavirus Effect of Remdesivir. Drug Discov Ther. 2020;14(2):73-76. PubMed PMID: 32378648.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rapid review for the anti-coronavirus effect of remdesivir. AU - Li,Ziyi, AU - Wang,Xiaojie, AU - Cao,Donglin, AU - Sun,Ruilin, AU - Li,Cheng, AU - Li,Guowei, PY - 2020/5/8/entrez PY - 2020/5/8/pubmed PY - 2020/5/10/medline KW - COVID-19 KW - SARS-CoV-2 KW - effect KW - remdesivir KW - safety SP - 73 EP - 76 JF - Drug discoveries & therapeutics JO - Drug Discov Ther VL - 14 IS - 2 N2 - The outbreak of SARS-CoV-2 rapidly spread across China and worldwide. Remdesivir had been proposed as a promising option for treating coronavirus disease 2019 (COVID-19). We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. Even though remdesivir was proposed as a promising option for treating COVID-19 based on laboratory experiments and reports from compassionate use, its safety and effect in humans requires high-quality evidence from well-designed and adequately-powered clinical trials for further clarification. SN - 1881-784X UR - https://www.unboundmedicine.com/medline/citation/32378648/Rapid_review_for_the_anti_coronavirus_effect_of_remdesivir_ DB - PRIME DP - Unbound Medicine ER -