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An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report.
Braz J Infect Dis. 2020 May - Jun; 24(3):247-249.BJ

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and has spread rapidly worldwide. We present a mild SARS-CoV-2 infection in a baby with non-productive cough and normal chest computed tomography, in whom only anal swabs tested positive by real-time PCR testing for SARS-CoV-2. She was given atomization inhalation therapy with recombinant human interferon alfa-1b for 10 days. Her anal swabs remained positive for eight days, whereas her throat swabs were persistently negative by real-time PCR testing. Mild and asymptomatic cases, especially in children, might present with PCR negative pharyngeal/nasal swabs and PCR positive anal swabs. Those patients are potential sources of infection via fecal-oral transmission for COVID-19.

Authors+Show Affiliations

Pidu District People's Hospital, Department of Infectious Diseases, Chengdu, Sichuan Province, China.Pidu District People's Hospital, Department of Infectious Diseases, Chengdu, Sichuan Province, China.Pidu District People's Hospital, Department of Cardiology, Chengdu, Deyuan Chengdu, Sichuan Province, China.Pidu District People's Hospital, Department of Cardiology, Chengdu, Deyuan Chengdu, Sichuan Province, China.Changxing County Hospital, of Traditional Chinese Medicine, Department of Respiratory Medicine, Huzhou, Zhejiang Province, China. Electronic address: wzyxysgq@126.com.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

32389618

Citation

Li, Juan, et al. "An Infant With a Mild SARS-CoV-2 Infection Detected Only By Anal Swabs: a Case Report." The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases, vol. 24, no. 3, 2020, pp. 247-249.
Li J, Feng J, Liu TH, et al. An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report. Braz J Infect Dis. 2020;24(3):247-249.
Li, J., Feng, J., Liu, T. H., Xu, F. C., & Song, G. Q. (2020). An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report. The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases, 24(3), 247-249. https://doi.org/10.1016/j.bjid.2020.04.009
Li J, et al. An Infant With a Mild SARS-CoV-2 Infection Detected Only By Anal Swabs: a Case Report. Braz J Infect Dis. 2020 May - Jun;24(3):247-249. PubMed PMID: 32389618.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report. AU - Li,Juan, AU - Feng,Jing, AU - Liu,Tian-Hu, AU - Xu,Feng-Cheng, AU - Song,Guo-Qiang, Y1 - 2020/05/06/ PY - 2020/03/20/received PY - 2020/04/19/revised PY - 2020/04/20/accepted PY - 2020/5/12/pubmed PY - 2020/7/24/medline PY - 2020/5/12/entrez KW - Anal swab KW - Baby KW - Severe acute respiratory syndrome coronavirus 2 SP - 247 EP - 249 JF - The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases JO - Braz J Infect Dis VL - 24 IS - 3 N2 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and has spread rapidly worldwide. We present a mild SARS-CoV-2 infection in a baby with non-productive cough and normal chest computed tomography, in whom only anal swabs tested positive by real-time PCR testing for SARS-CoV-2. She was given atomization inhalation therapy with recombinant human interferon alfa-1b for 10 days. Her anal swabs remained positive for eight days, whereas her throat swabs were persistently negative by real-time PCR testing. Mild and asymptomatic cases, especially in children, might present with PCR negative pharyngeal/nasal swabs and PCR positive anal swabs. Those patients are potential sources of infection via fecal-oral transmission for COVID-19. SN - 1678-4391 UR - https://www.unboundmedicine.com/medline/citation/32389618/An_infant_with_a_mild_SARS_CoV_2_infection_detected_only_by_anal_swabs:_a_case_report_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1413-8670(20)30043-X DB - PRIME DP - Unbound Medicine ER -