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[Chloroquine as a possible treatment for COVID-19].
Ned Tijdschr Geneeskd. 2020 Mar 11; 164NT

Abstract

Since the outbreak of COVID-19, chloroquine has been mentioned as a possible treatment. In vitro studies have shown anti-viral activity of chloroquine against SARS-CoV-2. Recently, the Dutch National Institute for Public Health and the Environment published treatment options for antiviral treatment for COVID-19 where chloroquine was suggested as first choice for off-label treatment, beside remdesivir en lopinavir/ritonavir. In this commentary, we provide a background and history of chloroquine, the evidence for antiviral efficacy of chloroquine and the arguments for off-label use of chloroquine in COVID-19.

Authors+Show Affiliations

Tergooi Ziekenhuis, afd. Interne Geneeskunde, Hilversum. Contact: Jeroen Coumou (jcoumou@tergooi.nl).Tergooi Ziekenhuis, afd. Interne Geneeskunde, Hilversum.

Pub Type(s)

Journal Article

Language

dut

PubMed ID

32391999

Citation

Coumou, Jeroen, and Peter J. de Vries. "[Chloroquine as a Possible Treatment for COVID-19]." Nederlands Tijdschrift Voor Geneeskunde, vol. 164, 2020.
Coumou J, de Vries PJ. [Chloroquine as a possible treatment for COVID-19]. Ned Tijdschr Geneeskd. 2020;164.
Coumou, J., & de Vries, P. J. (2020). [Chloroquine as a possible treatment for COVID-19]. Nederlands Tijdschrift Voor Geneeskunde, 164.
Coumou J, de Vries PJ. [Chloroquine as a Possible Treatment for COVID-19]. Ned Tijdschr Geneeskd. 2020 Mar 11;164 PubMed PMID: 32391999.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Chloroquine as a possible treatment for COVID-19]. AU - Coumou,Jeroen, AU - de Vries,Peter J, Y1 - 2020/03/11/ PY - 2020/5/12/entrez PY - 2020/5/12/pubmed PY - 2020/5/21/medline JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 164 N2 - Since the outbreak of COVID-19, chloroquine has been mentioned as a possible treatment. In vitro studies have shown anti-viral activity of chloroquine against SARS-CoV-2. Recently, the Dutch National Institute for Public Health and the Environment published treatment options for antiviral treatment for COVID-19 where chloroquine was suggested as first choice for off-label treatment, beside remdesivir en lopinavir/ritonavir. In this commentary, we provide a background and history of chloroquine, the evidence for antiviral efficacy of chloroquine and the arguments for off-label use of chloroquine in COVID-19. SN - 1876-8784 UR - https://www.unboundmedicine.com/medline/citation/32391999/[Chloroquine_as_a_possible_treatment_for_COVID_19]_ DB - PRIME DP - Unbound Medicine ER -