Tags

Type your tag names separated by a space and hit enter

Does Aerobic Vaginitis Have Adverse Pregnancy Outcomes? Prospective Observational Study.
Infect Dis Obstet Gynecol. 2020; 2020:5842150.ID

Abstract

Background

Aerobic vaginitis (AV) is an aberration within the balanced vaginal microbiota. Only few reports have documented the adverse pregnancy outcomes related to AV. Nonetheless, the exact role of AV in pregnancy and the potential benefit of its screening need further study. Our goal was to evaluate the association between aerobic vaginitis (AV) in late pregnancy and maternal and neonatal outcomes.

Methods

In this prospective observational study, a total of 600 singleton pregnant women with intact fetal membranes at a gestational age of 34-36 weeks were recruited (one hundred women with AV and 500 pregnant women without AV). The study protocol excluded patients with other forms of vaginal infection. Pregnancy outcomes were traced and documented. The primary outcome was the association between AV and preterm labor. The current study compared the maternal and neonatal outcomes among pregnant women with and without AV in unadjusted and adjusted analyses with the odds ratio (OR) and 95% confidence interval (CI) reported.

Results

There was an association between AV and with preterm birth (adjusted OR 3.06, 95% CI 1.58-5.95) and prelabor rupture of membranes (adjusted OR 6.17, 95% CI 3.24-11.7). For neonatal outcomes, AV was associated with a higher incidence of neonatal ICU admission (adjusted OR 2.19, 95% CI 1.1-4.34). Severe forms of AV significantly increased the incidence of PTB (p = 0.0014) and PROM (p = 0.0094) when compared to less severe forms of AV.

Conclusion

AV is common in late pregnancy and is linked to a diversity of adversative pregnancy outcomes including preterm birth, PROM, and neonatal ICU admission. Moreover, the incidence of PTB and PROM might further increase with the severity of AV. Clinicians should pay more consideration to vaginal microbiota assessment during pregnancy.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Department of Obstetrics and Gynecology, Bugshan Hospital, Jeddah, Saudi Arabia.Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.Department of Obstetrics and Gynecology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.Laboratory Department, Ministry of Interior Hospitals, Cairo, Egypt.Department of Obstetrics and Gynecology, Nasser Institute for Research and Treatment, Cairo, Egypt.Department of Pediatrics and Neonatology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32395067

Citation

Hassan, Mahmoud F., et al. "Does Aerobic Vaginitis Have Adverse Pregnancy Outcomes? Prospective Observational Study." Infectious Diseases in Obstetrics and Gynecology, vol. 2020, 2020, p. 5842150.
Hassan MF, Rund NMA, El-Tohamy O, et al. Does Aerobic Vaginitis Have Adverse Pregnancy Outcomes? Prospective Observational Study. Infect Dis Obstet Gynecol. 2020;2020:5842150.
Hassan, M. F., Rund, N. M. A., El-Tohamy, O., Moussa, M., Ali, Y. Z., Moussa, N., Abdelrazik, A. A., & Abdallah, E. A. A. (2020). Does Aerobic Vaginitis Have Adverse Pregnancy Outcomes? Prospective Observational Study. Infectious Diseases in Obstetrics and Gynecology, 2020, 5842150. https://doi.org/10.1155/2020/5842150
Hassan MF, et al. Does Aerobic Vaginitis Have Adverse Pregnancy Outcomes? Prospective Observational Study. Infect Dis Obstet Gynecol. 2020;2020:5842150. PubMed PMID: 32395067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does Aerobic Vaginitis Have Adverse Pregnancy Outcomes? Prospective Observational Study. AU - Hassan,Mahmoud F, AU - Rund,Nancy M A, AU - El-Tohamy,Osama, AU - Moussa,Mahmoud, AU - Ali,Yahia Z, AU - Moussa,Nehal, AU - Abdelrazik,Ahmed A, AU - Abdallah,Enas A A, Y1 - 2020/01/18/ PY - 2019/06/14/received PY - 2019/11/02/revised PY - 2019/12/19/accepted PY - 2020/5/13/entrez PY - 2020/5/13/pubmed PY - 2020/5/13/medline SP - 5842150 EP - 5842150 JF - Infectious diseases in obstetrics and gynecology JO - Infect Dis Obstet Gynecol VL - 2020 N2 - Background: Aerobic vaginitis (AV) is an aberration within the balanced vaginal microbiota. Only few reports have documented the adverse pregnancy outcomes related to AV. Nonetheless, the exact role of AV in pregnancy and the potential benefit of its screening need further study. Our goal was to evaluate the association between aerobic vaginitis (AV) in late pregnancy and maternal and neonatal outcomes. Methods: In this prospective observational study, a total of 600 singleton pregnant women with intact fetal membranes at a gestational age of 34-36 weeks were recruited (one hundred women with AV and 500 pregnant women without AV). The study protocol excluded patients with other forms of vaginal infection. Pregnancy outcomes were traced and documented. The primary outcome was the association between AV and preterm labor. The current study compared the maternal and neonatal outcomes among pregnant women with and without AV in unadjusted and adjusted analyses with the odds ratio (OR) and 95% confidence interval (CI) reported. Results: There was an association between AV and with preterm birth (adjusted OR 3.06, 95% CI 1.58-5.95) and prelabor rupture of membranes (adjusted OR 6.17, 95% CI 3.24-11.7). For neonatal outcomes, AV was associated with a higher incidence of neonatal ICU admission (adjusted OR 2.19, 95% CI 1.1-4.34). Severe forms of AV significantly increased the incidence of PTB (p = 0.0014) and PROM (p = 0.0094) when compared to less severe forms of AV. Conclusion: AV is common in late pregnancy and is linked to a diversity of adversative pregnancy outcomes including preterm birth, PROM, and neonatal ICU admission. Moreover, the incidence of PTB and PROM might further increase with the severity of AV. Clinicians should pay more consideration to vaginal microbiota assessment during pregnancy. SN - 1098-0997 UR - https://www.unboundmedicine.com/medline/citation/32395067/Does_Aerobic_Vaginitis_Have_Adverse_Pregnancy_Outcomes_Prospective_Observational_Study L2 - https://doi.org/10.1155/2020/5842150 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.