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Recent progress on the diagnosis of 2019 Novel Coronavirus.
Transbound Emerg Dis. 2020 Jul; 67(4):1485-1491.TE

Abstract

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic. Therefore, convenient, timely and accurate detection of SARS-CoV-2 is urgently needed. Here, we review the types, characteristics and shortcomings of various detection methods, as well as perspectives for the SARS-CoV-2 diagnosis. Clinically, nucleic acid-based methods are sensitive but prone to false-positive. The antibody-based method has slightly lower sensitivity but higher accuracy. Therefore, it is suggested to combine the two methods to improve the detection accuracy of COVID-19.

Authors+Show Affiliations

The Chinese Peoples' Liberation Army 964 Hospital, Changchun, China.College of Animal Sciences, Jilin University, Changchun, China.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32395897

Citation

Li, Chun, and Linzhu Ren. "Recent Progress On the Diagnosis of 2019 Novel Coronavirus." Transboundary and Emerging Diseases, vol. 67, no. 4, 2020, pp. 1485-1491.
Li C, Ren L. Recent progress on the diagnosis of 2019 Novel Coronavirus. Transbound Emerg Dis. 2020;67(4):1485-1491.
Li, C., & Ren, L. (2020). Recent progress on the diagnosis of 2019 Novel Coronavirus. Transboundary and Emerging Diseases, 67(4), 1485-1491. https://doi.org/10.1111/tbed.13620
Li C, Ren L. Recent Progress On the Diagnosis of 2019 Novel Coronavirus. Transbound Emerg Dis. 2020;67(4):1485-1491. PubMed PMID: 32395897.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recent progress on the diagnosis of 2019 Novel Coronavirus. AU - Li,Chun, AU - Ren,Linzhu, Y1 - 2020/05/31/ PY - 2020/03/14/received PY - 2020/05/03/revised PY - 2020/05/04/accepted PY - 2020/5/13/pubmed PY - 2020/7/15/medline PY - 2020/5/13/entrez KW - Corona Virus Disease 2019 (COVID-19) KW - antibody KW - clustered regularly interspaced short palindromic repeats (CRISPR) KW - detection KW - real-time RT-PCR KW - reverse transcription loop-mediated isothermal amplification (RT-LAMP) KW - severe acute respiratory syndrome coronavirus 2 (2019 Novel Coronavirus SARS-CoV-2) SP - 1485 EP - 1491 JF - Transboundary and emerging diseases JO - Transbound Emerg Dis VL - 67 IS - 4 N2 - Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic. Therefore, convenient, timely and accurate detection of SARS-CoV-2 is urgently needed. Here, we review the types, characteristics and shortcomings of various detection methods, as well as perspectives for the SARS-CoV-2 diagnosis. Clinically, nucleic acid-based methods are sensitive but prone to false-positive. The antibody-based method has slightly lower sensitivity but higher accuracy. Therefore, it is suggested to combine the two methods to improve the detection accuracy of COVID-19. SN - 1865-1682 UR - https://www.unboundmedicine.com/medline/citation/32395897/Recent_progress_on_the_diagnosis_of_2019_Novel_Coronavirus_ L2 - https://doi.org/10.1111/tbed.13620 DB - PRIME DP - Unbound Medicine ER -