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A technical report from the Italian SARS-CoV-2 outbreak. Postmortem sampling and autopsy investigation in cases of suspected or probable COVID-19.
Forensic Sci Med Pathol. 2020 09; 16(3):471-476.FS

Abstract

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a coronavirus responsible for COVID-19 (coronavirus disease 2019) which resulted in a cluster of cases of pneumonia that originated in China around 31 December 2019 and has subsequently spread across the globe. Currently, COVID-19 represents a health emergency worldwide, leading, in severe cases, to pneumonia, severe acute respiratory syndrome, multiorgan dysfunction or failure, and death. In the context of limited scientific knowledge and evidence of SARS-CoV-2 infection, guidance is becoming increasingly necessary for pathologists who have to perform postmortem investigations on COVID-19 cases. The aim of the present report is to share a procedure applicable to cases of COVID-19-related death, particularly in cases of death without medical intervention and in the absence of an ascertained SARS-CoV-2 infection and/or COVID-19 diagnosis, therefore providing support for diagnostic activity in the present COVID-19 pandemic. For this purpose, a standard operating procedure for correct swab collection, autopsy investigation and tissue sampling is provided.

Authors+Show Affiliations

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336, 00185, Rome, Italy.Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336, 00185, Rome, Italy.Department of Medicine, Surgery and Health, University of Trieste, Strada di Fiume 44, 34149, Trieste, Italy.Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336, 00185, Rome, Italy. vfinesc@tin.it.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32399755

Citation

Santurro, Alessandro, et al. "A Technical Report From the Italian SARS-CoV-2 Outbreak. Postmortem Sampling and Autopsy Investigation in Cases of Suspected or Probable COVID-19." Forensic Science, Medicine, and Pathology, vol. 16, no. 3, 2020, pp. 471-476.
Santurro A, Scopetti M, D'Errico S, et al. A technical report from the Italian SARS-CoV-2 outbreak. Postmortem sampling and autopsy investigation in cases of suspected or probable COVID-19. Forensic Sci Med Pathol. 2020;16(3):471-476.
Santurro, A., Scopetti, M., D'Errico, S., & Fineschi, V. (2020). A technical report from the Italian SARS-CoV-2 outbreak. Postmortem sampling and autopsy investigation in cases of suspected or probable COVID-19. Forensic Science, Medicine, and Pathology, 16(3), 471-476. https://doi.org/10.1007/s12024-020-00258-9
Santurro A, et al. A Technical Report From the Italian SARS-CoV-2 Outbreak. Postmortem Sampling and Autopsy Investigation in Cases of Suspected or Probable COVID-19. Forensic Sci Med Pathol. 2020;16(3):471-476. PubMed PMID: 32399755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A technical report from the Italian SARS-CoV-2 outbreak. Postmortem sampling and autopsy investigation in cases of suspected or probable COVID-19. AU - Santurro,Alessandro, AU - Scopetti,Matteo, AU - D'Errico,Stefano, AU - Fineschi,Vittorio, Y1 - 2020/05/12/ PY - 2020/04/24/accepted PY - 2020/5/14/pubmed PY - 2020/9/10/medline PY - 2020/5/14/entrez KW - Autopsy investigation KW - COVID-19 KW - Postmortem diagnosis KW - SARS-CoV-2 KW - Virological diagnosis SP - 471 EP - 476 JF - Forensic science, medicine, and pathology JO - Forensic Sci Med Pathol VL - 16 IS - 3 N2 - SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a coronavirus responsible for COVID-19 (coronavirus disease 2019) which resulted in a cluster of cases of pneumonia that originated in China around 31 December 2019 and has subsequently spread across the globe. Currently, COVID-19 represents a health emergency worldwide, leading, in severe cases, to pneumonia, severe acute respiratory syndrome, multiorgan dysfunction or failure, and death. In the context of limited scientific knowledge and evidence of SARS-CoV-2 infection, guidance is becoming increasingly necessary for pathologists who have to perform postmortem investigations on COVID-19 cases. The aim of the present report is to share a procedure applicable to cases of COVID-19-related death, particularly in cases of death without medical intervention and in the absence of an ascertained SARS-CoV-2 infection and/or COVID-19 diagnosis, therefore providing support for diagnostic activity in the present COVID-19 pandemic. For this purpose, a standard operating procedure for correct swab collection, autopsy investigation and tissue sampling is provided. SN - 1556-2891 UR - https://www.unboundmedicine.com/medline/citation/32399755/A_technical_report_from_the_Italian_SARS_CoV_2_outbreak__Postmortem_sampling_and_autopsy_investigation_in_cases_of_suspected_or_probable_COVID_19_ L2 - https://dx.doi.org/10.1007/s12024-020-00258-9 DB - PRIME DP - Unbound Medicine ER -