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[Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection].
Ugeskr Laeger. 2020 05 11; 182(20)UL

Abstract

The severity of COVID-19 disease has led to an urgent need for the discovery of new treatments. Thus, global stocks of hydroxychloroquine (HCQ) have been put under pressure with a study of 26 patients treated with HCQ during their infection with SARS-CoV-2. Despite the study's lack of quality, several countries' medicines agencies subsequently issued guidelines for the use of HCQ for COVID-19. This review aims to elucidate potential mechanisms, which make HCQ treatment interesting in the fight against SARS-CoV-2 infection, as well as the current evidence for clinical use of HCQ to treat COVID-19.

Authors+Show Affiliations

annetrol@rm.dk.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

dan

PubMed ID

32400380

Citation

Troldborg, Anne, et al. "[Lack of Clinical Evidence for the Use of Hydroxychloroquine to Treat SARS-CoV-2 Infection]." Ugeskrift for Laeger, vol. 182, no. 20, 2020.
Troldborg A, Bartels LE, Deleuran B. [Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection]. Ugeskr Laeger. 2020;182(20).
Troldborg, A., Bartels, L. E., & Deleuran, B. (2020). [Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection]. Ugeskrift for Laeger, 182(20).
Troldborg A, Bartels LE, Deleuran B. [Lack of Clinical Evidence for the Use of Hydroxychloroquine to Treat SARS-CoV-2 Infection]. Ugeskr Laeger. 2020 05 11;182(20) PubMed PMID: 32400380.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection]. AU - Troldborg,Anne, AU - Bartels,Lars Erik, AU - Deleuran,Bent, PY - 2020/5/14/entrez PY - 2020/5/14/pubmed PY - 2020/5/19/medline JF - Ugeskrift for laeger JO - Ugeskr Laeger VL - 182 IS - 20 N2 - The severity of COVID-19 disease has led to an urgent need for the discovery of new treatments. Thus, global stocks of hydroxychloroquine (HCQ) have been put under pressure with a study of 26 patients treated with HCQ during their infection with SARS-CoV-2. Despite the study's lack of quality, several countries' medicines agencies subsequently issued guidelines for the use of HCQ for COVID-19. This review aims to elucidate potential mechanisms, which make HCQ treatment interesting in the fight against SARS-CoV-2 infection, as well as the current evidence for clinical use of HCQ to treat COVID-19. SN - 1603-6824 UR - https://www.unboundmedicine.com/medline/citation/32400380/[Lack_of_clinical_evidence_for_the_use_of_hydroxychloroquine_to_treat_SARS_CoV_2_infection]_ DB - PRIME DP - Unbound Medicine ER -