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Megaloblastic anaemia in a 9-weeks old infant: A case report.
J Pak Med Assoc. 2020 May; 70(5):923-925.JP

Abstract

Megaloblastic anaemia due to vitamin B12 and folic acid deficiency is uncommon in infancy and rarely reported in infants below 3 months of age. We hereby report a case of megaloblastic anaemia in a 9-weeks old infant having fever from 7th week of life. Blood picture showed pancytopenia and diagnosis was confirmed on bone marrow biopsy and serum level of vitamins. Patient positively responded to vitamin B12 and folic acid supplementation. Infants with pancytopenia even younger than 2 months, should also be investigated for vitamin B12 and folate deficiency. Mother of the baby was not antenatally investigated for anaemia. Prompt antenatal diagnosis and treatment of mothers can reduce the incidence in the infants.

Authors+Show Affiliations

Department of Paediatrics, Federal Government Polyclinic (PGMI), Islamabad, Pakistan.Department of Paediatrics, Federal Government Polyclinic (PGMI), Islamabad, Pakistan.Department of Paediatrics, Federal Government Polyclinic (PGMI), Islamabad, Pakistan.Department of Paediatrics, Federal Government Polyclinic (PGMI), Islamabad, Pakistan.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

32400755

Citation

Afzal, Tehreem, et al. "Megaloblastic Anaemia in a 9-weeks Old Infant: a Case Report." JPMA. the Journal of the Pakistan Medical Association, vol. 70, no. 5, 2020, pp. 923-925.
Afzal T, Ashraf N, Munir S, et al. Megaloblastic anaemia in a 9-weeks old infant: A case report. J Pak Med Assoc. 2020;70(5):923-925.
Afzal, T., Ashraf, N., Munir, S., & Tabassum, R. (2020). Megaloblastic anaemia in a 9-weeks old infant: A case report. JPMA. the Journal of the Pakistan Medical Association, 70(5), 923-925. https://doi.org/10.5455/JPMA.23379
Afzal T, et al. Megaloblastic Anaemia in a 9-weeks Old Infant: a Case Report. J Pak Med Assoc. 2020;70(5):923-925. PubMed PMID: 32400755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Megaloblastic anaemia in a 9-weeks old infant: A case report. AU - Afzal,Tehreem, AU - Ashraf,Naveed, AU - Munir,Shahzad, AU - Tabassum,Rabia, PY - 2020/5/14/entrez PY - 2020/5/14/pubmed PY - 2021/3/6/medline KW - Megaloblastic anaemia, vitamin B12 deficiency, folic acid deficiency, infant SP - 923 EP - 925 JF - JPMA. The Journal of the Pakistan Medical Association JO - J Pak Med Assoc VL - 70 IS - 5 N2 - Megaloblastic anaemia due to vitamin B12 and folic acid deficiency is uncommon in infancy and rarely reported in infants below 3 months of age. We hereby report a case of megaloblastic anaemia in a 9-weeks old infant having fever from 7th week of life. Blood picture showed pancytopenia and diagnosis was confirmed on bone marrow biopsy and serum level of vitamins. Patient positively responded to vitamin B12 and folic acid supplementation. Infants with pancytopenia even younger than 2 months, should also be investigated for vitamin B12 and folate deficiency. Mother of the baby was not antenatally investigated for anaemia. Prompt antenatal diagnosis and treatment of mothers can reduce the incidence in the infants. SN - 0030-9982 UR - https://www.unboundmedicine.com/medline/citation/32400755/Megaloblastic_anaemia_in_a_9_weeks_old_infant:_A_case_report_ L2 - http://jpma.org.pk/full_article-text.php?article_id=9833 DB - PRIME DP - Unbound Medicine ER -