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Novel human coronavirus (SARS-CoV-2): A lesson from animal coronaviruses.
Vet Microbiol. 2020 May; 244:108693.VM

Abstract

The recent pandemic caused by the novel human coronavirus, referrred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), not only is having a great impact on the health care systems and economies in all continents but it is also causing radical changes of common habits and life styles. The novel coronavirus (CoV) recognises, with high probability, a zoonotic origin but the role of animals in the SARS-CoV-2 epidemiology is still largely unknown. However, CoVs have been known in animals since several decades, so that veterinary coronavirologists have a great expertise on how to face CoV infections in animals, which could represent a model for SARS-CoV-2 infection in humans. In the present paper, we provide an up-to-date review of the literature currently available on animal CoVs, focusing on the molecular mechanisms that are responsible for the emergence of novel CoV strains with different antigenic, biologic and/or pathogenetic features. A full comprehension of the mechanisms driving the evolution of animal CoVs will help better understand the emergence, spreading, and evolution of SARS-CoV-2.

Authors+Show Affiliations

Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy. Electronic address: nicola.decaro@uniba.it.Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale', Teramo, Italy.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32402329

Citation

Decaro, Nicola, and Alessio Lorusso. "Novel Human Coronavirus (SARS-CoV-2): a Lesson From Animal Coronaviruses." Veterinary Microbiology, vol. 244, 2020, p. 108693.
Decaro N, Lorusso A. Novel human coronavirus (SARS-CoV-2): A lesson from animal coronaviruses. Vet Microbiol. 2020;244:108693.
Decaro, N., & Lorusso, A. (2020). Novel human coronavirus (SARS-CoV-2): A lesson from animal coronaviruses. Veterinary Microbiology, 244, 108693. https://doi.org/10.1016/j.vetmic.2020.108693
Decaro N, Lorusso A. Novel Human Coronavirus (SARS-CoV-2): a Lesson From Animal Coronaviruses. Vet Microbiol. 2020;244:108693. PubMed PMID: 32402329.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Novel human coronavirus (SARS-CoV-2): A lesson from animal coronaviruses. AU - Decaro,Nicola, AU - Lorusso,Alessio, Y1 - 2020/04/14/ PY - 2020/03/10/received PY - 2020/04/10/revised PY - 2020/04/10/accepted PY - 2020/5/14/entrez PY - 2020/5/14/pubmed PY - 2020/5/16/medline KW - Animal coronaviruses KW - COVID-19 KW - Genetic plasticity KW - Host switch KW - Novel human coronavirus KW - SARS-CoV-2 KW - Tissue tropism SP - 108693 EP - 108693 JF - Veterinary microbiology JO - Vet Microbiol VL - 244 N2 - The recent pandemic caused by the novel human coronavirus, referrred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), not only is having a great impact on the health care systems and economies in all continents but it is also causing radical changes of common habits and life styles. The novel coronavirus (CoV) recognises, with high probability, a zoonotic origin but the role of animals in the SARS-CoV-2 epidemiology is still largely unknown. However, CoVs have been known in animals since several decades, so that veterinary coronavirologists have a great expertise on how to face CoV infections in animals, which could represent a model for SARS-CoV-2 infection in humans. In the present paper, we provide an up-to-date review of the literature currently available on animal CoVs, focusing on the molecular mechanisms that are responsible for the emergence of novel CoV strains with different antigenic, biologic and/or pathogenetic features. A full comprehension of the mechanisms driving the evolution of animal CoVs will help better understand the emergence, spreading, and evolution of SARS-CoV-2. SN - 1873-2542 UR - https://www.unboundmedicine.com/medline/citation/32402329/Novel_human_coronavirus__SARS_CoV_2_:_A_lesson_from_animal_coronaviruses_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-1135(20)30293-5 DB - PRIME DP - Unbound Medicine ER -