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The role of subjective responses in electronic cigarette uptake and substitution in adult smokers.
Drug Alcohol Depend. 2020 07 01; 212:107999.DA

Abstract

BACKGROUND

While a majority of cigarette smokers who use electronic cigarettes (e-cigarettes) choose to continue using cigarettes, completely switching to e-cigarettes is necessary to reduce tobacco-related harm. Whether specific subjective responses to e-cigarettes are associated with extent of smoking reduction and complete switching from cigarettes to e-cigarettes is unclear. This study determined whether initial subjective responses to e-cigarettes related to the successful substitution of e-cigarettes for cigarettes and extent of cigarette and e-cigarette use.

METHODS

Adult cigarette smokers (N = 58) uninterested in quitting were asked to completely substitute their cigarettes with an e-cigarette (Vuse Solo) for 8 weeks. At week 1, subjective responses to e-cigarettes were measured using the Product Evaluation Scale and Drug Effects/Liking Survey. A Poisson regression examined whether any of these initial subjective responses were associated with smoke-free days, e-cigarette puffs, and cigarettes smoked between weeks 6 and 8 after adjustment for potential confounders. A logistic regression examined the relationship between subjective measures and exhaled carbon monoxide (CO) verified 7-day abstinence at week 8 after adjustment for potential confounders.

RESULTS

Following Holm's p-value adjustment, e-cigarette liking and desire were associated with increased e-cigarette use (adjusted p < 0.01) and decreased cigarette use (adjusted p < 0.05). Measures of psychological reward and drug liking were associated with 7-day abstinence, however this association was no longer significant following p-value adjustment.

CONCLUSIONS

Initial subjective responses were related to cigarette and e-cigarette use at weeks 6-8, but not smoke-free days or CO-verified 7-day abstinence.

Links

PMC Free PDF

Authors+Show Affiliations

Gades MS
University of Minnesota, Department of Psychology, 75 E. River Road, Minneapolis, MN, 55454, United States. Electronic address: gades020@umn.edu.
Petersen A
University of Minnesota, School of Public Health Division of Biostatistics, 420 Delaware St. SE, Minneapolis, MN, 55455, United States.
Meier E
University of Wisconsin Stevens Point, Department of Psychology, Science Building, Stevens Point, WI, United States.
Lindgren BR
University of Minnesota, Department of Psychiatry and Masonic Cancer Center, 717 Delaware St SE, Minneapolis, MN, 55414, United States.
O'Connor RJ
Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States.
Shields PG
Ohio State University, Columbus, OH, United States.
Hatsukami D
University of Minnesota, Department of Psychiatry and Masonic Cancer Center, 717 Delaware St SE, Minneapolis, MN, 55414, United States.

MeSH

AdultAgedCigarette SmokingElectronic Nicotine Delivery SystemsFemaleHumansMaleMiddle AgedRewardSmokersSmoking CessationSurveys and QuestionnairesVapingYoung Adult

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

32409110

Citation

Gades, Mari S., et al. "The Role of Subjective Responses in Electronic Cigarette Uptake and Substitution in Adult Smokers." Drug and Alcohol Dependence, vol. 212, 2020, p. 107999.
Gades MS, Petersen A, Meier E, et al. The role of subjective responses in electronic cigarette uptake and substitution in adult smokers. Drug Alcohol Depend. 2020;212:107999.
Gades, M. S., Petersen, A., Meier, E., Lindgren, B. R., O'Connor, R. J., Shields, P. G., & Hatsukami, D. (2020). The role of subjective responses in electronic cigarette uptake and substitution in adult smokers. Drug and Alcohol Dependence, 212, 107999. https://doi.org/10.1016/j.drugalcdep.2020.107999
Gades MS, et al. The Role of Subjective Responses in Electronic Cigarette Uptake and Substitution in Adult Smokers. Drug Alcohol Depend. 2020 07 1;212:107999. PubMed PMID: 32409110.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of subjective responses in electronic cigarette uptake and substitution in adult smokers. AU - Gades,Mari S, AU - Petersen,Ashley, AU - Meier,Ellen, AU - Lindgren,Bruce R, AU - O'Connor,Richard J, AU - Shields,Peter G, AU - Hatsukami,Dorothy, Y1 - 2020/04/25/ PY - 2020/01/06/received PY - 2020/03/19/revised PY - 2020/03/28/accepted PY - 2020/5/16/pubmed PY - 2021/2/23/medline PY - 2020/5/16/entrez KW - Abuse liability KW - Electronic cigarettes KW - Responses KW - Smoking KW - Subjective KW - Tobacco regulatory science SP - 107999 EP - 107999 JF - Drug and alcohol dependence JO - Drug Alcohol Depend VL - 212 N2 - BACKGROUND: While a majority of cigarette smokers who use electronic cigarettes (e-cigarettes) choose to continue using cigarettes, completely switching to e-cigarettes is necessary to reduce tobacco-related harm. Whether specific subjective responses to e-cigarettes are associated with extent of smoking reduction and complete switching from cigarettes to e-cigarettes is unclear. This study determined whether initial subjective responses to e-cigarettes related to the successful substitution of e-cigarettes for cigarettes and extent of cigarette and e-cigarette use. METHODS: Adult cigarette smokers (N = 58) uninterested in quitting were asked to completely substitute their cigarettes with an e-cigarette (Vuse Solo) for 8 weeks. At week 1, subjective responses to e-cigarettes were measured using the Product Evaluation Scale and Drug Effects/Liking Survey. A Poisson regression examined whether any of these initial subjective responses were associated with smoke-free days, e-cigarette puffs, and cigarettes smoked between weeks 6 and 8 after adjustment for potential confounders. A logistic regression examined the relationship between subjective measures and exhaled carbon monoxide (CO) verified 7-day abstinence at week 8 after adjustment for potential confounders. RESULTS: Following Holm's p-value adjustment, e-cigarette liking and desire were associated with increased e-cigarette use (adjusted p < 0.01) and decreased cigarette use (adjusted p < 0.05). Measures of psychological reward and drug liking were associated with 7-day abstinence, however this association was no longer significant following p-value adjustment. CONCLUSIONS: Initial subjective responses were related to cigarette and e-cigarette use at weeks 6-8, but not smoke-free days or CO-verified 7-day abstinence. SN - 1879-0046 UR - https://www.unboundmedicine.com/medline/citation/32409110/The_role_of_subjective_responses_in_electronic_cigarette_uptake_and_substitution_in_adult_smokers_ DB - PRIME DP - Unbound Medicine ER -