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2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored.
Curr Atheroscler Rep. 2020 05 07; 22(3):14.CA

Abstract

PURPOSE OF THE REVIEW

Coronavirus disease 2019 (COVID-19), a new infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has reached a pandemic status. Although SARSCoV-2 causes primarily respiratory problems, concurrent cardiac injury cannot be ignored since it may be an independent predictor for adverse outcomes. To resolve these issues, we aim to summarize the prevalence and its underlying mechanisms of acute cardiac injury in the setting of SARS-CoV-2 infection.

RECENT FINDINGS

The main clinical manifestation of SARS-CoV-2 infection is pneumonia, cardiovascular complications have also been identified in the earliest reported cases from Wuhan, the epicenter of the outbreak. Given the SARS-CoV-2 likely uses the angiotensin-converting enzyme-2 (ACE2) receptors as its host receptor, ACE2-related signaling pathways may play a key role in mediating myocardial injury. SARS-CoV-2 infection related acute cardiac injury cannot be ignored, and its underlying mechanisms remain speculated. We would suggest that health professionals investigate cardiac function as part of the routine care.

Authors+Show Affiliations

Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, People's Republic of China.Department of Clinical Research, Federal University of Uberlândia, Uberlândia, Brazil. leonardoroever@hotmail.com.Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, People's Republic of China.Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, 300211, People's Republic of China. liutongdoc@126.com.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32415481

Citation

Wang, Yueying, et al. "2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored." Current Atherosclerosis Reports, vol. 22, no. 3, 2020, p. 14.
Wang Y, Roever L, Tse G, et al. 2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored. Curr Atheroscler Rep. 2020;22(3):14.
Wang, Y., Roever, L., Tse, G., & Liu, T. (2020). 2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored. Current Atherosclerosis Reports, 22(3), 14. https://doi.org/10.1007/s11883-020-00842-y
Wang Y, et al. 2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored. Curr Atheroscler Rep. 2020 05 7;22(3):14. PubMed PMID: 32415481.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 2019-Novel Coronavirus-Related Acute Cardiac Injury Cannot Be Ignored. AU - Wang,Yueying, AU - Roever,Leonardo, AU - Tse,Gary, AU - Liu,Tong, Y1 - 2020/05/07/ PY - 2020/5/17/entrez PY - 2020/5/18/pubmed PY - 2020/5/22/medline KW - 2019-nCoV KW - Angiotensin-converting enzyme-2 KW - COVID-19 KW - Cardiac injury KW - SARS‐CoV‐2 SP - 14 EP - 14 JF - Current atherosclerosis reports JO - Curr Atheroscler Rep VL - 22 IS - 3 N2 - PURPOSE OF THE REVIEW: Coronavirus disease 2019 (COVID-19), a new infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has reached a pandemic status. Although SARSCoV-2 causes primarily respiratory problems, concurrent cardiac injury cannot be ignored since it may be an independent predictor for adverse outcomes. To resolve these issues, we aim to summarize the prevalence and its underlying mechanisms of acute cardiac injury in the setting of SARS-CoV-2 infection. RECENT FINDINGS: The main clinical manifestation of SARS-CoV-2 infection is pneumonia, cardiovascular complications have also been identified in the earliest reported cases from Wuhan, the epicenter of the outbreak. Given the SARS-CoV-2 likely uses the angiotensin-converting enzyme-2 (ACE2) receptors as its host receptor, ACE2-related signaling pathways may play a key role in mediating myocardial injury. SARS-CoV-2 infection related acute cardiac injury cannot be ignored, and its underlying mechanisms remain speculated. We would suggest that health professionals investigate cardiac function as part of the routine care. SN - 1534-6242 UR - https://www.unboundmedicine.com/medline/citation/32415481/2019_Novel_Coronavirus_Related_Acute_Cardiac_Injury_Cannot_Be_Ignored_ L2 - https://dx.doi.org/10.1007/s11883-020-00842-y DB - PRIME DP - Unbound Medicine ER -