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COVID-19 managed with early non-invasive ventilation and a bundle pharmacotherapy: A case report.
World J Clin Cases. 2020 May 06; 8(9):1705-1712.WJ

Abstract

BACKGROUND

The coronavirus disease 2019 (COVID-19) pandemic has become an immense public health burden, first in China and subsequently worldwide. Developing effective control measures for COVID-19, especially measures that can halt the worsening of severe cases to a critical status is of urgent importance.

CASE SUMMARY

A 52-year-old woman presented with a high fever (38.8 °C), chills, dizziness, and weakness. Epidemiologically, she had not been to Wuhan where COVID-19 emerged and did not have a family history of a disease cluster. A blood test yielded a white blood cell count of 4.41 × 109/L (60.6 ± 2.67% neutrophils and 30.4 ± 1.34% lymphocytes). Chest imaging revealed bilateral ground-glass lung changes. Based on a positive nasopharyngeal swab nucleic acid test result and clinical characteristics, the patient was diagnosed with COVID-19. Following treatment with early non-invasive ventilation and a bundle pharmacotherapy, she recovered with a good outcome.

CONCLUSION

Early non-invasive ventilation with a bundle pharmacotherapy may be an effective treatment regimen for the broader population of patients with COVID-19.

Authors+Show Affiliations

Department of Intensive Care Unit, the Third Affiliated Hospital of Shenzhen University, Shenzhen 518001, Guangdong Province, China.Department of Intensive Care Unit, the Second People's Hospital of Shenzhen, Shenzhen 518001, Guangdong Province, China.Department of Intensive Care Unit, Shenzhen People's Hospital, First Affiliated Hospital of Southern University of Science and Technology, the Second Affiliated Hospital of Jinan University, Shenzhen 518020, Guangdong Province, China. liuxueyan100916@163.com.Department of Intensive Care Unit, the Third People's Hospital of Shenzhen, Shenzhen 518001, Guangdong Province, China.Department of Intensive Care Unit, Shenzhen Longgang Central Hospital, Shenzhen 518001, Guangdong Province, China.Department of Intensive Care Unit, Shenzhen Baoan District People's Hospital, Shenzhen 518001, Guangdong Province, China.Department of Intensive Care Unit, Shenzhen Longgang Central Hospital, Shenzhen 518001, Guangdong Province, China.Department of Intensive Care Unit, the Third People's Hospital of Shenzhen, Shenzhen 518001, Guangdong Province, China.Department of Dermatology, Shenzhen University General Hospital, Shenzhen 518067, Guangdong Province, China.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

32420305

Citation

Peng, Mian, et al. "COVID-19 Managed With Early Non-invasive Ventilation and a Bundle Pharmacotherapy: a Case Report." World Journal of Clinical Cases, vol. 8, no. 9, 2020, pp. 1705-1712.
Peng M, Ren D, Liu XY, et al. COVID-19 managed with early non-invasive ventilation and a bundle pharmacotherapy: A case report. World J Clin Cases. 2020;8(9):1705-1712.
Peng, M., Ren, D., Liu, X. Y., Li, J. X., Chen, R. L., Yu, B. J., Liu, Y. F., Meng, X., & Lyu, Y. S. (2020). COVID-19 managed with early non-invasive ventilation and a bundle pharmacotherapy: A case report. World Journal of Clinical Cases, 8(9), 1705-1712. https://doi.org/10.12998/wjcc.v8.i9.1705
Peng M, et al. COVID-19 Managed With Early Non-invasive Ventilation and a Bundle Pharmacotherapy: a Case Report. World J Clin Cases. 2020 May 6;8(9):1705-1712. PubMed PMID: 32420305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - COVID-19 managed with early non-invasive ventilation and a bundle pharmacotherapy: A case report. AU - Peng,Mian, AU - Ren,Di, AU - Liu,Xue-Yan, AU - Li,Jin-Xiu, AU - Chen,Rong-Lin, AU - Yu,Bao-Jun, AU - Liu,Yong-Feng, AU - Meng,Xi, AU - Lyu,Yan-Si, PY - 2020/03/11/received PY - 2020/04/09/revised PY - 2020/04/17/accepted PY - 2020/5/19/entrez PY - 2020/5/19/pubmed PY - 2020/5/19/medline KW - Bundle pharmacotherapy KW - COVID-19 KW - Case report KW - Coronavirus KW - Non-invasive ventilation KW - Pneumonia SP - 1705 EP - 1712 JF - World journal of clinical cases JO - World J Clin Cases VL - 8 IS - 9 N2 - BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has become an immense public health burden, first in China and subsequently worldwide. Developing effective control measures for COVID-19, especially measures that can halt the worsening of severe cases to a critical status is of urgent importance. CASE SUMMARY: A 52-year-old woman presented with a high fever (38.8 °C), chills, dizziness, and weakness. Epidemiologically, she had not been to Wuhan where COVID-19 emerged and did not have a family history of a disease cluster. A blood test yielded a white blood cell count of 4.41 × 109/L (60.6 ± 2.67% neutrophils and 30.4 ± 1.34% lymphocytes). Chest imaging revealed bilateral ground-glass lung changes. Based on a positive nasopharyngeal swab nucleic acid test result and clinical characteristics, the patient was diagnosed with COVID-19. Following treatment with early non-invasive ventilation and a bundle pharmacotherapy, she recovered with a good outcome. CONCLUSION: Early non-invasive ventilation with a bundle pharmacotherapy may be an effective treatment regimen for the broader population of patients with COVID-19. SN - 2307-8960 UR - https://www.unboundmedicine.com/medline/citation/32420305/COVID_19_managed_with_early_non_invasive_ventilation_and_a_bundle_pharmacotherapy:_A_case_report_ L2 - https://www.wjgnet.com/2307-8960/full/v8/i9/1705.htm DB - PRIME DP - Unbound Medicine ER -
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