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Children are unlikely to be the main drivers of the COVID-19 pandemic - A systematic review.
Acta Paediatr. 2020 08; 109(8):1525-1530.AP

Abstract

AIM

Many countries have closed schools and kindergartens to minimise COVID-19, but the role that children play in disease transmission is unclear.

METHODS

A systematic literature review of the MEDLINE and EMBASE databases and medRxiv/bioRxiv preprint servers to 11 May 2020 identified published and unpublished papers on COVID-19 transmission by children.

RESULTS

We identified 700 scientific papers and letters and 47 full texts were studied in detail. Children accounted for a small fraction of COVID-19 cases and mostly had social contacts with peers or parents, rather than older people at risk of severe disease. Data on viral loads were scarce, but indicated that children may have lower levels than adults, partly because they often have fewer symptoms, and this should decrease the transmission risk. Household transmission studies showed that children were rarely the index case and case studies suggested that children with COVID-19 seldom caused outbreaks. However, it is highly likely that children can transmit the SARS-COV-2 virus, which causes COVID-19, and even asymptomatic children can have viral loads.

CONCLUSION

Children are unlikely to be the main drivers of the pandemic. Opening up schools and kindergartens is unlikely to impact COVID-19 mortality rates in older people.

Authors+Show Affiliations

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Department of Paediatrics, Orebro University Hospital, Orebro, Sweden. Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK. Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Pub Type(s)

Journal Article
Systematic Review

Language

eng

PubMed ID

32430964

Citation

Ludvigsson, Jonas F.. "Children Are Unlikely to Be the Main Drivers of the COVID-19 Pandemic - a Systematic Review." Acta Paediatrica (Oslo, Norway : 1992), vol. 109, no. 8, 2020, pp. 1525-1530.
Ludvigsson JF. Children are unlikely to be the main drivers of the COVID-19 pandemic - A systematic review. Acta Paediatr. 2020;109(8):1525-1530.
Ludvigsson, J. F. (2020). Children are unlikely to be the main drivers of the COVID-19 pandemic - A systematic review. Acta Paediatrica (Oslo, Norway : 1992), 109(8), 1525-1530. https://doi.org/10.1111/apa.15371
Ludvigsson JF. Children Are Unlikely to Be the Main Drivers of the COVID-19 Pandemic - a Systematic Review. Acta Paediatr. 2020;109(8):1525-1530. PubMed PMID: 32430964.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Children are unlikely to be the main drivers of the COVID-19 pandemic - A systematic review. A1 - Ludvigsson,Jonas F, Y1 - 2020/06/17/ PY - 2020/05/15/received PY - 2020/05/18/accepted PY - 2020/5/21/pubmed PY - 2020/7/16/medline PY - 2020/5/21/entrez KW - COVID-19 KW - children KW - coronavirus KW - pandemic KW - transmission SP - 1525 EP - 1530 JF - Acta paediatrica (Oslo, Norway : 1992) JO - Acta Paediatr. VL - 109 IS - 8 N2 - AIM: Many countries have closed schools and kindergartens to minimise COVID-19, but the role that children play in disease transmission is unclear. METHODS: A systematic literature review of the MEDLINE and EMBASE databases and medRxiv/bioRxiv preprint servers to 11 May 2020 identified published and unpublished papers on COVID-19 transmission by children. RESULTS: We identified 700 scientific papers and letters and 47 full texts were studied in detail. Children accounted for a small fraction of COVID-19 cases and mostly had social contacts with peers or parents, rather than older people at risk of severe disease. Data on viral loads were scarce, but indicated that children may have lower levels than adults, partly because they often have fewer symptoms, and this should decrease the transmission risk. Household transmission studies showed that children were rarely the index case and case studies suggested that children with COVID-19 seldom caused outbreaks. However, it is highly likely that children can transmit the SARS-COV-2 virus, which causes COVID-19, and even asymptomatic children can have viral loads. CONCLUSION: Children are unlikely to be the main drivers of the pandemic. Opening up schools and kindergartens is unlikely to impact COVID-19 mortality rates in older people. SN - 1651-2227 UR - https://www.unboundmedicine.com/medline/citation/32430964/Children_are_unlikely_to_be_the_main_drivers_of_the_COVID_19_pandemic___A_systematic_review_ L2 - https://doi.org/10.1111/apa.15371 DB - PRIME DP - Unbound Medicine ER -
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