Tags

Type your tag names separated by a space and hit enter

Perinatal depressive and anxiety symptoms of pregnant women during the coronavirus disease 2019 outbreak in China.
Am J Obstet Gynecol. 2020 08; 223(2):240.e1-240.e9.AJ

Abstract

BACKGROUND

On January 20, 2020, a new coronavirus epidemic with human-to-human transmission was officially declared by the Chinese government, which caused significant public panic in China. In light of the coronavirus disease 2019 outbreak, pregnant women may be particularly vulnerable and in special need for preventive mental health strategies. Thus far, no reports exist to investigate the mental health response of pregnant women to the coronavirus disease 2019 outbreak.

OBJECTIVE

This study aimed to examine the impact of coronavirus disease 2019 outbreak on the prevalence of depressive and anxiety symptoms and the corresponding risk factors among pregnant women across China.

STUDY DESIGN

A multicenter, cross-sectional study was initiated in early December 2019 to identify mental health concerns in pregnancy using the Edinburgh Postnatal Depression Scale. This study provided a unique opportunity to compare the mental status of pregnant women before and after the declaration of the coronavirus disease 2019 epidemic. A total of 4124 pregnant women during their third trimester from 25 hospitals in 10 provinces across China were examined in this cross-sectional study from January 1, 2020, to February 9, 2020. Of these women, 1285 were assessed after January 20, 2020, when the coronavirus epidemic was publicly declared and 2839 were assessed before this pivotal time point. The internationally recommended Edinburgh Postnatal Depression Scale was used to assess maternal depression and anxiety symptoms. Prevalence rates and risk factors were compared between the pre- and poststudy groups.

RESULTS

Pregnant women assessed after the declaration of coronavirus disease 2019 epidemic had significantly higher rates of depressive symptoms (26.0% vs 29.6%, P=.02) than women assessed before the epidemic declaration. These women were also more likely to have thoughts of self-harm (P=.005). The depressive rates were positively associated with the number of newly confirmed cases of coronavirus disease 2019 (P=.003), suspected infections (P=.004), and deaths per day (P=.001). Pregnant women who were underweight before pregnancy, primiparous, younger than 35 years, employed full time, in middle income category, and had appropriate living space were at increased risk for developing depressive and anxiety symptoms during the outbreak.

CONCLUSION

Major life-threatening public health events such as the coronavirus disease 2019 outbreak may increase the risk for mental illness among pregnant women, including thoughts of self-harm. Strategies targeting maternal stress and isolation such as effective risk communication and the provision of psychological first aid may be particularly useful to prevent negative outcomes for women and their fetuses.

Authors+Show Affiliations

International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China; Chinese Maternal and Child Health Association, Beijing, China.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.Shaoxing Maternity and Child Health Care Hospital, Shaoxing, Zhejiang, China.Jiashan Maternity and Child Health Care Hospital, Jiaxing, Zhejiang, China.Dalian Maternal and Childcare Health Hospital, Dalian, Liaoning, China.Wenzhou People's Hospital, Wenzhou, Zhejiang, China.Hangzhou Women's Hospital, Hangzhou, Zhejiang, China.Fuzhou Maternal and Child Health Care Hospital, Fuzhou, Jiangxi, China.Songjiang Maternity and Child Health Hospital, Shanghai, China.Hunan Maternal and Child Health Care Hospital, Changsha, Hunan, China.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Affiliated Hospital of Yan'an University, Yan'an, Shaanxi, China.Enze Obstetrics and Gynecology Hospital Affiliated to Taizhou Hospital of Zhejiang Province, Taizhou, Zhejiang, China.Taizhou Hospital of Zhejiang Province, Taizhou, Zhejiang, China.Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.Hainan Women and Children's Medical Center, Haikou, Hainan, China.First People's Hospital of Wuhu City, Wuhu, Anhui, China.People's Hospital of Changshan, Quzhou, Zhejiang, China.Shengzhou Maternity and Child Health Hospital, Shengzhou, Zhejiang, China.Wenchang Maternity and Child Health Care Hospital, Wenchang, Hainan, China.Huzhou Maternity and Child Health Care Hospital, Huzhou, Zhejiang, China.Karamay Central Hospital of XinJiang, Xinjiang, China.Ningbo Yinzhou People's Hospital, Ningbo, Zhejiang, China.Fuyang Women and Children's Hospital, Hangzhou, Zhejiang, China.Ningbo Women and Children's Hospital, Ningbo, Zhejiang, China.Key Laboratory of Reproductive Genetics (Zhejiang University), Ministry of Education, Hangzhou, Zhejiang, China.Ningbo University Affiliated Hospital of Medical School, Ningbo, Zhejiang, China.School of Public Health, Zhejiang University, Hangzhou, Zhejiang, China.Sir Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Ontario, Canada.International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China; Key Laboratory of Reproductive Genetics (Zhejiang University), Ministry of Education, Hangzhou, Zhejiang, China; Chinese Maternal and Child Health Association, Beijing, China. Electronic address: huanghefg@sjtu.edu.cn.

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

32437665

Citation

Wu, Yanting, et al. "Perinatal Depressive and Anxiety Symptoms of Pregnant Women During the Coronavirus Disease 2019 Outbreak in China." American Journal of Obstetrics and Gynecology, vol. 223, no. 2, 2020, pp. 240.e1-240.e9.
Wu Y, Zhang C, Liu H, et al. Perinatal depressive and anxiety symptoms of pregnant women during the coronavirus disease 2019 outbreak in China. Am J Obstet Gynecol. 2020;223(2):240.e1-240.e9.
Wu, Y., Zhang, C., Liu, H., Duan, C., Li, C., Fan, J., Li, H., Chen, L., Xu, H., Li, X., Guo, Y., Wang, Y., Li, X., Li, J., Zhang, T., You, Y., Li, H., Yang, S., Tao, X., ... Huang, H. F. (2020). Perinatal depressive and anxiety symptoms of pregnant women during the coronavirus disease 2019 outbreak in China. American Journal of Obstetrics and Gynecology, 223(2), e1-e9. https://doi.org/10.1016/j.ajog.2020.05.009
Wu Y, et al. Perinatal Depressive and Anxiety Symptoms of Pregnant Women During the Coronavirus Disease 2019 Outbreak in China. Am J Obstet Gynecol. 2020;223(2):240.e1-240.e9. PubMed PMID: 32437665.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Perinatal depressive and anxiety symptoms of pregnant women during the coronavirus disease 2019 outbreak in China. AU - Wu,Yanting, AU - Zhang,Chen, AU - Liu,Han, AU - Duan,Chenchi, AU - Li,Cheng, AU - Fan,Jianxia, AU - Li,Hong, AU - Chen,Lei, AU - Xu,Hualin, AU - Li,Xiangjuan, AU - Guo,Yi, AU - Wang,Yeping, AU - Li,Xiufeng, AU - Li,Jing, AU - Zhang,Ting, AU - You,Yiping, AU - Li,Hongmei, AU - Yang,Shuangqi, AU - Tao,Xiaoling, AU - Xu,Yajuan, AU - Lao,Haihong, AU - Wen,Ming, AU - Zhou,Yan, AU - Wang,Junying, AU - Chen,Yuhua, AU - Meng,Diyun, AU - Zhai,Jingli, AU - Ye,Youchun, AU - Zhong,Qinwen, AU - Yang,Xiuping, AU - Zhang,Dan, AU - Zhang,Jing, AU - Wu,Xifeng, AU - Chen,Wei, AU - Dennis,Cindy-Lee, AU - Huang,He-Feng, Y1 - 2020/05/11/ PY - 2020/04/27/received PY - 2020/05/06/accepted PY - 2020/5/22/pubmed PY - 2020/8/11/medline PY - 2020/5/22/entrez KW - COVID-19 KW - Edinburgh Postnatal Depression Scale KW - perinatal anxiety KW - perinatal depression SP - 240.e1 EP - 240.e9 JF - American journal of obstetrics and gynecology JO - Am J Obstet Gynecol VL - 223 IS - 2 N2 - BACKGROUND: On January 20, 2020, a new coronavirus epidemic with human-to-human transmission was officially declared by the Chinese government, which caused significant public panic in China. In light of the coronavirus disease 2019 outbreak, pregnant women may be particularly vulnerable and in special need for preventive mental health strategies. Thus far, no reports exist to investigate the mental health response of pregnant women to the coronavirus disease 2019 outbreak. OBJECTIVE: This study aimed to examine the impact of coronavirus disease 2019 outbreak on the prevalence of depressive and anxiety symptoms and the corresponding risk factors among pregnant women across China. STUDY DESIGN: A multicenter, cross-sectional study was initiated in early December 2019 to identify mental health concerns in pregnancy using the Edinburgh Postnatal Depression Scale. This study provided a unique opportunity to compare the mental status of pregnant women before and after the declaration of the coronavirus disease 2019 epidemic. A total of 4124 pregnant women during their third trimester from 25 hospitals in 10 provinces across China were examined in this cross-sectional study from January 1, 2020, to February 9, 2020. Of these women, 1285 were assessed after January 20, 2020, when the coronavirus epidemic was publicly declared and 2839 were assessed before this pivotal time point. The internationally recommended Edinburgh Postnatal Depression Scale was used to assess maternal depression and anxiety symptoms. Prevalence rates and risk factors were compared between the pre- and poststudy groups. RESULTS: Pregnant women assessed after the declaration of coronavirus disease 2019 epidemic had significantly higher rates of depressive symptoms (26.0% vs 29.6%, P=.02) than women assessed before the epidemic declaration. These women were also more likely to have thoughts of self-harm (P=.005). The depressive rates were positively associated with the number of newly confirmed cases of coronavirus disease 2019 (P=.003), suspected infections (P=.004), and deaths per day (P=.001). Pregnant women who were underweight before pregnancy, primiparous, younger than 35 years, employed full time, in middle income category, and had appropriate living space were at increased risk for developing depressive and anxiety symptoms during the outbreak. CONCLUSION: Major life-threatening public health events such as the coronavirus disease 2019 outbreak may increase the risk for mental illness among pregnant women, including thoughts of self-harm. Strategies targeting maternal stress and isolation such as effective risk communication and the provision of psychological first aid may be particularly useful to prevent negative outcomes for women and their fetuses. SN - 1097-6868 UR - https://www.unboundmedicine.com/medline/citation/32437665/Perinatal_depressive_and_anxiety_symptoms_of_pregnant_women_during_the_coronavirus_disease_2019_outbreak_in_China_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9378(20)30534-2 DB - PRIME DP - Unbound Medicine ER -