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Clinical Characteristics and Outcomes of 421 Patients With Coronavirus Disease 2019 Treated in a Mobile Cabin Hospital.
Chest. 2020 09; 158(3):939-946.Chest

Abstract

Background

In December 2019, a novel coronavirus-associated pneumonia, now known as coronavirus disease 2019 (COVID-19), was first detected in Wuhan, China. To prevent the rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and treat patients with mild symptoms, sports stadiums and convention centers were reconstructed into mobile hospitals.

Research Question

It is unknown whether a mobile cabin hospital can provide a safe treatment site for patients with mild COVID-19 symptoms.

Study Design and Methods

This study retrospectively reviewed the medical records of 421 patients with COVID-19 admitted to a mobile cabin hospital in Wuhan from February 9, 2020, to March 5, 2020. Clinical data comprised patient age, sex, clinical presentation, chest imaging, nucleic acid testing, length of hospitalization, and outcomes.

Results

Of the patients who were discharged from the cabin hospital, 362 (86.0%) were categorized as recovered; 14.0% developed severe symptoms and were transferred to a designated hospital. The most common presenting symptoms were fever (60.6%) and cough (52.0%); 5.2% exhibited no obvious symptoms. High fever (> 39.0°C) was more common in severe cases than in recovered cases (18.6% vs 6.6%). The distribution of lung lesions was peripheral in 85.0% of patients, multifocal in 69.4%, and bilateral in 68.2%. The most common pattern was ground-glass opacity (67.7%), followed by patchy shadowing (49.2%). The incidence of patchy shadowing was higher in patients with severe disease (66.1%) than in those who recovered (31.8%, P < .0001). The median length of hospitalization was 17 days (interquartile range, 14-19 days), and the median time taken for positive real-time reverse transcriptase polymerase chain reaction results to become negative in recovered patients was 8 days (interquartile range, 6-10 days).

Interpretation

Mobile cabin hospitals provide a safe treatment site for patients with mild COVID-19 symptoms and offer an effective isolation area to prevent the spread of severe acute respiratory syndrome coronavirus 2.

Authors+Show Affiliations

Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Allergy, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Radiology, Xuancheng Central Hospital, Xuancheng, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China. Electronic address: chenjincao2012@163.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32437696

Citation

Wang, Wei, et al. "Clinical Characteristics and Outcomes of 421 Patients With Coronavirus Disease 2019 Treated in a Mobile Cabin Hospital." Chest, vol. 158, no. 3, 2020, pp. 939-946.
Wang W, Xin C, Xiong Z, et al. Clinical Characteristics and Outcomes of 421 Patients With Coronavirus Disease 2019 Treated in a Mobile Cabin Hospital. Chest. 2020;158(3):939-946.
Wang, W., Xin, C., Xiong, Z., Yan, X., Cai, Y., Zhou, K., Xie, C., Zhang, T., Wu, X., Liu, K., Li, Z., & Chen, J. (2020). Clinical Characteristics and Outcomes of 421 Patients With Coronavirus Disease 2019 Treated in a Mobile Cabin Hospital. Chest, 158(3), 939-946. https://doi.org/10.1016/j.chest.2020.05.515
Wang W, et al. Clinical Characteristics and Outcomes of 421 Patients With Coronavirus Disease 2019 Treated in a Mobile Cabin Hospital. Chest. 2020;158(3):939-946. PubMed PMID: 32437696.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical Characteristics and Outcomes of 421 Patients With Coronavirus Disease 2019 Treated in a Mobile Cabin Hospital. AU - Wang,Wei, AU - Xin,Can, AU - Xiong,Zhongwei, AU - Yan,Xixi, AU - Cai,Yuankun, AU - Zhou,Keyao, AU - Xie,Chuanshun, AU - Zhang,Tingbao, AU - Wu,Xiaohui, AU - Liu,Kui, AU - Li,Zhiqiang, AU - Chen,Jincao, Y1 - 2020/05/08/ PY - 2020/5/22/pubmed PY - 2020/9/18/medline PY - 2020/5/22/entrez KW - COVID-19 KW - COVID-19, coronavirus disease 2019 KW - RT-PCR, real-time reverse transcription polymerase chain reaction KW - SARS-CoV-2 KW - SARS-CoV-2, severe acute respiratory syndrome coronavirus 2 KW - clinical characteristics KW - mobile cabin hospital KW - outcomes SP - 939 EP - 946 JF - Chest JO - Chest VL - 158 IS - 3 N2 - Background: In December 2019, a novel coronavirus-associated pneumonia, now known as coronavirus disease 2019 (COVID-19), was first detected in Wuhan, China. To prevent the rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and treat patients with mild symptoms, sports stadiums and convention centers were reconstructed into mobile hospitals. Research Question: It is unknown whether a mobile cabin hospital can provide a safe treatment site for patients with mild COVID-19 symptoms. Study Design and Methods: This study retrospectively reviewed the medical records of 421 patients with COVID-19 admitted to a mobile cabin hospital in Wuhan from February 9, 2020, to March 5, 2020. Clinical data comprised patient age, sex, clinical presentation, chest imaging, nucleic acid testing, length of hospitalization, and outcomes. Results: Of the patients who were discharged from the cabin hospital, 362 (86.0%) were categorized as recovered; 14.0% developed severe symptoms and were transferred to a designated hospital. The most common presenting symptoms were fever (60.6%) and cough (52.0%); 5.2% exhibited no obvious symptoms. High fever (> 39.0°C) was more common in severe cases than in recovered cases (18.6% vs 6.6%). The distribution of lung lesions was peripheral in 85.0% of patients, multifocal in 69.4%, and bilateral in 68.2%. The most common pattern was ground-glass opacity (67.7%), followed by patchy shadowing (49.2%). The incidence of patchy shadowing was higher in patients with severe disease (66.1%) than in those who recovered (31.8%, P < .0001). The median length of hospitalization was 17 days (interquartile range, 14-19 days), and the median time taken for positive real-time reverse transcriptase polymerase chain reaction results to become negative in recovered patients was 8 days (interquartile range, 6-10 days). Interpretation: Mobile cabin hospitals provide a safe treatment site for patients with mild COVID-19 symptoms and offer an effective isolation area to prevent the spread of severe acute respiratory syndrome coronavirus 2. SN - 1931-3543 UR - https://www.unboundmedicine.com/medline/citation/32437696/Clinical_Characteristics_and_Outcomes_of_421_Patients_With_Coronavirus_Disease_2019_Treated_in_a_Mobile_Cabin_Hospital_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0012-3692(20)31391-X DB - PRIME DP - Unbound Medicine ER -