Tags

Type your tag names separated by a space and hit enter

Clinical Insights into the Gastrointestinal Manifestations of COVID-19.
Dig Dis Sci. 2020 07; 65(7):1932-1939.DD

Abstract

The month of December 2019 became a critical part of the time of humanity when the first case of coronavirus disease 2019 (COVID-19) was reported in the Wuhan, Hubei Province in China. As of April 13th, 2020, there have been approximately 1.9 million cases and 199,000 deaths across the world, which were associated with COVID-19. The COVID-19 is the seventh coronavirus to be identified to infect humans. In the past, Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome were the two coronaviruses that infected humans with a high fatality, particularly among the elderly. Fatalities due to COVID-19 are higher in patients older than 50 years of age or those with multimorbid conditions. The COVID-19 is mainly transmitted through respiratory droplets, with the most common symptoms being high fever, cough, myalgia, atypical symptoms included sputum production, headache, hemoptysis and diarrhea. However, the incubation period can range from 2 to 14 days without any symptoms. It is particularly true with gastrointestinal (GI) symptoms in which patients can still shed the virus even after pulmonary symptoms have resolved. Given the high percentage of COVID-19 patients that present with GI symptoms (e.g., nausea and diarrhea), screening patients for GI symptoms remain essential. Recently, cases of fecal-oral transmission of COVID-19 have been confirmed in the USA and China, indicating that the virus can replicate in both the respiratory and digestive tract. Moreover, the epidemiology, clinical characteristics, diagnostic procedures, treatments and prevention of the gastrointestinal manifestations of COVID-19 remain to be elucidated.

Authors+Show Affiliations

Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX, 79430, USA.Department of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, 5001 El Paso Drive, El Paso, TX, 79905, USA.Department of Medicine, Bassett Medical Center, 1 Atwell Road, Cooperstown, NY, 13326, USA.The Wright Center for Graduate Medical Education, 501 S. Washington Avenue, Scranton, PA, 18503, USA. doc.hemant@yahoo.com.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32447742

Citation

Kopel, Jonathan, et al. "Clinical Insights Into the Gastrointestinal Manifestations of COVID-19." Digestive Diseases and Sciences, vol. 65, no. 7, 2020, pp. 1932-1939.
Kopel J, Perisetti A, Gajendran M, et al. Clinical Insights into the Gastrointestinal Manifestations of COVID-19. Dig Dis Sci. 2020;65(7):1932-1939.
Kopel, J., Perisetti, A., Gajendran, M., Boregowda, U., & Goyal, H. (2020). Clinical Insights into the Gastrointestinal Manifestations of COVID-19. Digestive Diseases and Sciences, 65(7), 1932-1939. https://doi.org/10.1007/s10620-020-06362-8
Kopel J, et al. Clinical Insights Into the Gastrointestinal Manifestations of COVID-19. Dig Dis Sci. 2020;65(7):1932-1939. PubMed PMID: 32447742.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical Insights into the Gastrointestinal Manifestations of COVID-19. AU - Kopel,Jonathan, AU - Perisetti,Abhilash, AU - Gajendran,Mahesh, AU - Boregowda,Umesha, AU - Goyal,Hemant, Y1 - 2020/05/23/ PY - 2020/03/25/received PY - 2020/05/21/accepted PY - 2020/5/25/pubmed PY - 2020/6/26/medline PY - 2020/5/25/entrez KW - COVID-19 KW - Coronavirus KW - Gastroenterology KW - Gastrointestinal symptoms KW - Pandemic SP - 1932 EP - 1939 JF - Digestive diseases and sciences JO - Dig Dis Sci VL - 65 IS - 7 N2 - The month of December 2019 became a critical part of the time of humanity when the first case of coronavirus disease 2019 (COVID-19) was reported in the Wuhan, Hubei Province in China. As of April 13th, 2020, there have been approximately 1.9 million cases and 199,000 deaths across the world, which were associated with COVID-19. The COVID-19 is the seventh coronavirus to be identified to infect humans. In the past, Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome were the two coronaviruses that infected humans with a high fatality, particularly among the elderly. Fatalities due to COVID-19 are higher in patients older than 50 years of age or those with multimorbid conditions. The COVID-19 is mainly transmitted through respiratory droplets, with the most common symptoms being high fever, cough, myalgia, atypical symptoms included sputum production, headache, hemoptysis and diarrhea. However, the incubation period can range from 2 to 14 days without any symptoms. It is particularly true with gastrointestinal (GI) symptoms in which patients can still shed the virus even after pulmonary symptoms have resolved. Given the high percentage of COVID-19 patients that present with GI symptoms (e.g., nausea and diarrhea), screening patients for GI symptoms remain essential. Recently, cases of fecal-oral transmission of COVID-19 have been confirmed in the USA and China, indicating that the virus can replicate in both the respiratory and digestive tract. Moreover, the epidemiology, clinical characteristics, diagnostic procedures, treatments and prevention of the gastrointestinal manifestations of COVID-19 remain to be elucidated. SN - 1573-2568 UR - https://www.unboundmedicine.com/medline/citation/32447742/Clinical_Insights_into_the_Gastrointestinal_Manifestations_of_COVID_19_ L2 - https://doi.org/10.1007/s10620-020-06362-8 DB - PRIME DP - Unbound Medicine ER -