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Regulation of the pentose phosphate cycle in bass (Dicentrarchus labrax L.) liver.
Rev Esp Fisiol. 1988 Dec; 44(4):433-9.RE

Abstract

The influence in the activities of the glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase produced by the ratio changes NADPH/NADP is studied. The intracellular ratios of 20 and 10 are enough to achieve total inhibition of these two enzymes, respectively. Measurements of a number of metabolic intermediates show that the concentrations of Krebs cycle compounds are higher than those of glycolytic pathway metabolites. From a consideration of these values, the regulation of the pentose phosphate cycle mainly by the intracellular NADPH/NADP ratio, is discussed.

Authors+Show Affiliations

Departamento de Bioquímica, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3244891

Citation

Medina-Puerta, M M., et al. "Regulation of the Pentose Phosphate Cycle in Bass (Dicentrarchus Labrax L.) Liver." Revista Espanola De Fisiologia, vol. 44, no. 4, 1988, pp. 433-9.
Medina-Puerta MM, Gallego-Iniesta M, Garrido-Pertierra A. Regulation of the pentose phosphate cycle in bass (Dicentrarchus labrax L.) liver. Rev Esp Fisiol. 1988;44(4):433-9.
Medina-Puerta, M. M., Gallego-Iniesta, M., & Garrido-Pertierra, A. (1988). Regulation of the pentose phosphate cycle in bass (Dicentrarchus labrax L.) liver. Revista Espanola De Fisiologia, 44(4), 433-9.
Medina-Puerta MM, Gallego-Iniesta M, Garrido-Pertierra A. Regulation of the Pentose Phosphate Cycle in Bass (Dicentrarchus Labrax L.) Liver. Rev Esp Fisiol. 1988;44(4):433-9. PubMed PMID: 3244891.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Regulation of the pentose phosphate cycle in bass (Dicentrarchus labrax L.) liver. AU - Medina-Puerta,M M, AU - Gallego-Iniesta,M, AU - Garrido-Pertierra,A, PY - 1988/12/1/pubmed PY - 1988/12/1/medline PY - 1988/12/1/entrez SP - 433 EP - 9 JF - Revista espanola de fisiologia JO - Rev. Esp. Fisiol. VL - 44 IS - 4 N2 - The influence in the activities of the glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase produced by the ratio changes NADPH/NADP is studied. The intracellular ratios of 20 and 10 are enough to achieve total inhibition of these two enzymes, respectively. Measurements of a number of metabolic intermediates show that the concentrations of Krebs cycle compounds are higher than those of glycolytic pathway metabolites. From a consideration of these values, the regulation of the pentose phosphate cycle mainly by the intracellular NADPH/NADP ratio, is discussed. SN - 0034-9402 UR - https://www.unboundmedicine.com/medline/citation/3244891/Regulation_of_the_pentose_phosphate_cycle_in_bass__Dicentrarchus_labrax_L___liver_ DB - PRIME DP - Unbound Medicine ER -