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Comparison of surgical outcomes in patients with Chiari Type I malformation receiving posterior fossa decompression with and without duraplasty.
Childs Nerv Syst. 2020 07; 36(7):1399-1405.CN

Abstract

PURPOSE

The goals of this study were to compare clinical outcomes in patients with Chiari Malformation Type I (CMI) receiving posterior fossa decompression with (PFDD) or without duraplasty (PFD).

METHODS

We conducted a retrospective analysis of 178 consecutive cases of 157 patients undergoing PFDD or PFD for CMI at Cohen Children's Medical Center between 2007 and 2017. Clinical improvement was defined as a clear reduction of preoperative symptoms after surgery as reported by patients and parents. An improvement of syrinx was derived from radiologic comparison of pre- and postoperative MR imaging. Chi-square analysis was performed to analyze the association between duraplasty and clinical parameters (alpha = 0.05).

RESULTS

The primary presenting complaint was headache (142/178; 80%), followed by neck, back, and upper extremity pain, and numbness or tingling (49/178; 28%). Seventy patients (78/178; 44%) underwent PFD, and 100 patients (100/178; 56%) underwent PFDD. Overall, 143 patients (143/178; 80%) experienced subjective improvement with no statistically significant difference between the two surgical techniques (p = 0.705). The number of patients receiving PFDD with syrinx improvement or stabilization (55/59; 93%) was statistically larger than those that received PFD (8/13; 62%) (p = 0.008). PFDD was associated with greater complications than PFD alone. There were 35 cases of reoperation overall (35/178; 19%), and there was no statistically significant difference in reoperation rate between PFD and PFDD (p = 0.255).

CONCLUSIONS

There appears to be a role for PFDD in patients with severe syringomyelia, but overall, PFD alone may be safely offered as the initial surgical intervention for symptomatic CMI patients.

Authors+Show Affiliations

Donald & Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Boulevard, Hempstead, NY, 11549, USA.Donald & Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Boulevard, Hempstead, NY, 11549, USA. srodgers@northwell.edu. Division of Pediatric Neurosurgery, Cohen Children's Medical Center of New York, New Hyde Park, NY, 11040, USA. srodgers@northwell.edu.Division of Pediatric Neurosurgery, Cohen Children's Medical Center of New York, New Hyde Park, NY, 11040, USA.Donald & Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Boulevard, Hempstead, NY, 11549, USA. Division of Pediatric Neurosurgery, Cohen Children's Medical Center of New York, New Hyde Park, NY, 11040, USA.Donald & Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Boulevard, Hempstead, NY, 11549, USA. Division of Pediatric Neurosurgery, Cohen Children's Medical Center of New York, New Hyde Park, NY, 11040, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32451665

Citation

Butensky, Samuel, et al. "Comparison of Surgical Outcomes in Patients With Chiari Type I Malformation Receiving Posterior Fossa Decompression With and Without Duraplasty." Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery, vol. 36, no. 7, 2020, pp. 1399-1405.
Butensky S, Rodgers S, Baron S, et al. Comparison of surgical outcomes in patients with Chiari Type I malformation receiving posterior fossa decompression with and without duraplasty. Childs Nerv Syst. 2020;36(7):1399-1405.
Butensky, S., Rodgers, S., Baron, S., Schneider, S., & Mittler, M. (2020). Comparison of surgical outcomes in patients with Chiari Type I malformation receiving posterior fossa decompression with and without duraplasty. Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery, 36(7), 1399-1405. https://doi.org/10.1007/s00381-020-04667-7
Butensky S, et al. Comparison of Surgical Outcomes in Patients With Chiari Type I Malformation Receiving Posterior Fossa Decompression With and Without Duraplasty. Childs Nerv Syst. 2020;36(7):1399-1405. PubMed PMID: 32451665.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of surgical outcomes in patients with Chiari Type I malformation receiving posterior fossa decompression with and without duraplasty. AU - Butensky,Samuel, AU - Rodgers,Shaun, AU - Baron,Shanna, AU - Schneider,Steven, AU - Mittler,Mark, Y1 - 2020/05/25/ PY - 2019/11/21/received PY - 2020/05/06/accepted PY - 2020/5/27/pubmed PY - 2021/6/22/medline PY - 2020/5/27/entrez KW - Chiari KW - Duraplasty KW - Extradural KW - Intradural KW - Syringomyelia KW - Syrinx SP - 1399 EP - 1405 JF - Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery JO - Childs Nerv Syst VL - 36 IS - 7 N2 - PURPOSE: The goals of this study were to compare clinical outcomes in patients with Chiari Malformation Type I (CMI) receiving posterior fossa decompression with (PFDD) or without duraplasty (PFD). METHODS: We conducted a retrospective analysis of 178 consecutive cases of 157 patients undergoing PFDD or PFD for CMI at Cohen Children's Medical Center between 2007 and 2017. Clinical improvement was defined as a clear reduction of preoperative symptoms after surgery as reported by patients and parents. An improvement of syrinx was derived from radiologic comparison of pre- and postoperative MR imaging. Chi-square analysis was performed to analyze the association between duraplasty and clinical parameters (alpha = 0.05). RESULTS: The primary presenting complaint was headache (142/178; 80%), followed by neck, back, and upper extremity pain, and numbness or tingling (49/178; 28%). Seventy patients (78/178; 44%) underwent PFD, and 100 patients (100/178; 56%) underwent PFDD. Overall, 143 patients (143/178; 80%) experienced subjective improvement with no statistically significant difference between the two surgical techniques (p = 0.705). The number of patients receiving PFDD with syrinx improvement or stabilization (55/59; 93%) was statistically larger than those that received PFD (8/13; 62%) (p = 0.008). PFDD was associated with greater complications than PFD alone. There were 35 cases of reoperation overall (35/178; 19%), and there was no statistically significant difference in reoperation rate between PFD and PFDD (p = 0.255). CONCLUSIONS: There appears to be a role for PFDD in patients with severe syringomyelia, but overall, PFD alone may be safely offered as the initial surgical intervention for symptomatic CMI patients. SN - 1433-0350 UR - https://www.unboundmedicine.com/medline/citation/32451665/Comparison_of_surgical_outcomes_in_patients_with_Chiari_Type_I_malformation_receiving_posterior_fossa_decompression_with_and_without_duraplasty_ DB - PRIME DP - Unbound Medicine ER -