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Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae).
Turk J Pharm Sci. 2020 Apr; 17(2):197-202.TJ

Abstract

Objectives

In the present study, the antioxidant potency of ethyl acetate (AcOEt) and methanol (MeOH) extracts from the aerial parts of Seseli L. species was investigated for the first time.

Materials and Methods

Seseli species L. such as Seseli andronakii Woronow ex Schischk., S. campestre Besser, S. corymbosum Boiss. & Heldr., S. gummiferum subsp. gummiferum Pall. ex Sm., S. hartvigii Parolly & Nordt, S. libanotis (L.) W.Koch, S. petraeum M.Bieb., S. peucedanoides (M.Bieb.) Koso-Pol., S. resinosum Freyn & Sint., and S. tortuosum L. growing in Turkey were collected and evaluated for their antioxidant capacity by using 1.1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and lipid peroxidation (LPO) inhibition methods.

Results

The highest activities as a scavenger of DPPH radicals were found in the AcOEt extracts of S. peucedanoides (M.Bieb.) Koso-Pol (IC50=0.49 mg/mL), and S. libanotis (IC50=0.75 mg/mL); α-tocopherol was used as a positive control. On the other hand, in the LPO assay, the highest activities were determined in AcOEt and MeOH extracts (at 5 mg/mL) of S. tortuosum and S. libanotis (84-94%).

Conclusion

This report gives important information about the antioxidant capacity of Seseli L. species. This research on antioxidant capacity proves that the use of some species used in Eastern Anatolia (in salads) is correct. With this screening study performed in Seseli L. species growing in Turkey, in the future, it is planned to isolate antioxidant compounds from the most active strains of Seseli L.

Authors+Show Affiliations

Ankara University Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey.Ankara University Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey. Lokman Hekim University Faculty of Pharmacy, Department of Pharmacognosy/Pharmaceutical Botany, Ankara, Turkey.Ankara University Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.Mardin Artuklu University, Kızıltepe Vocational Higher School, Mardin, Turkey.Ankara University Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32454780

Citation

Önder, Alev, et al. "Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae)." Turkish Journal of Pharmaceutical Sciences, vol. 17, no. 2, 2020, pp. 197-202.
Önder A, Çinar AS, Yilmaz Sarialtin S, et al. Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae). Turk J Pharm Sci. 2020;17(2):197-202.
Önder, A., Çinar, A. S., Yilmaz Sarialtin, S., Izgi, M. N., & Çoban, T. (2020). Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae). Turkish Journal of Pharmaceutical Sciences, 17(2), 197-202. https://doi.org/10.4274/tjps.galenos.2019.80488
Önder A, et al. Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae). Turk J Pharm Sci. 2020;17(2):197-202. PubMed PMID: 32454780.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae). AU - Önder,Alev, AU - Çinar,Ahsen Sevde, AU - Yilmaz Sarialtin,Sezen, AU - Izgi,Mehmet Necat, AU - Çoban,Tülay, Y1 - 2020/04/24/ PY - 2018/10/11/received PY - 2019/01/24/accepted PY - 2020/5/27/entrez PY - 2020/5/27/pubmed PY - 2020/5/27/medline KW - Antioxidant KW - Apiaceae KW - DPPH KW - LPO KW - Seseli SP - 197 EP - 202 JF - Turkish journal of pharmaceutical sciences JO - Turk J Pharm Sci VL - 17 IS - 2 N2 - Objectives: In the present study, the antioxidant potency of ethyl acetate (AcOEt) and methanol (MeOH) extracts from the aerial parts of Seseli L. species was investigated for the first time. Materials and Methods: Seseli species L. such as Seseli andronakii Woronow ex Schischk., S. campestre Besser, S. corymbosum Boiss. & Heldr., S. gummiferum subsp. gummiferum Pall. ex Sm., S. hartvigii Parolly & Nordt, S. libanotis (L.) W.Koch, S. petraeum M.Bieb., S. peucedanoides (M.Bieb.) Koso-Pol., S. resinosum Freyn & Sint., and S. tortuosum L. growing in Turkey were collected and evaluated for their antioxidant capacity by using 1.1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and lipid peroxidation (LPO) inhibition methods. Results: The highest activities as a scavenger of DPPH radicals were found in the AcOEt extracts of S. peucedanoides (M.Bieb.) Koso-Pol (IC50=0.49 mg/mL), and S. libanotis (IC50=0.75 mg/mL); α-tocopherol was used as a positive control. On the other hand, in the LPO assay, the highest activities were determined in AcOEt and MeOH extracts (at 5 mg/mL) of S. tortuosum and S. libanotis (84-94%). Conclusion: This report gives important information about the antioxidant capacity of Seseli L. species. This research on antioxidant capacity proves that the use of some species used in Eastern Anatolia (in salads) is correct. With this screening study performed in Seseli L. species growing in Turkey, in the future, it is planned to isolate antioxidant compounds from the most active strains of Seseli L. SN - 2148-6247 UR - https://www.unboundmedicine.com/medline/citation/32454780/Evaluation_of_the_Antioxidant_Potency_of_Seseli_L__Species__Apiaceae__ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32454780/ DB - PRIME DP - Unbound Medicine ER -
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