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Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during COVID-19 Pandemic.
Indian J Pediatr. 2020 09; 87(9):745-747.IJ

Abstract

There is a global concern of increasing number of children presenting with inflammatory syndrome with clinical features simulating Kawasaki disease, during ongoing COVID-19 pandemic. The authors report a very similar case of 5-y-old boy from a COVID-19 hotspot area who presented in late April 2020 with acute febrile illness with abdominal pain and loose stools followed by shock. On examination, child had bulbar conjunctivitis and extremity edema. Initial investigations showed high inflammatory parameters, elevated serum creatinine and liver enzymes. Echocardiography showed moderate LV dysfunction and normal coronaries. Cardiac enzymes were also elevated, suggesting myocarditis. He was treated with inotropic support, respiratory support with high flow nasal cannula, IV immunoglobulins, aspirin, steroids and diuretics. RT PCR for SARS-CoV-2 was negative twice. His clinical condition improved rapidly, was afebrile from day 2, inflammatory parameters decreased, left ventricular function improved and was discharged after 6 d of hospital stay.

Authors+Show Affiliations

Department of Pediatrics, Baby Memorial Hospital, Calicut, Kerala, 673004, India. abdrauf06@gmail.com.Department of Pediatrics, Baby Memorial Hospital, Calicut, Kerala, 673004, India.Department of Pediatrics, Baby Memorial Hospital, Calicut, Kerala, 673004, India.Department of Cardiology, Baby Memorial Hospital, Calicut, Kerala, India.Department of Pediatrics, Santi Hospital, Omassery, Calicut, Kerala, India.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

32462354

Citation

Rauf, Abdul, et al. "Multisystem Inflammatory Syndrome With Features of Atypical Kawasaki Disease During COVID-19 Pandemic." Indian Journal of Pediatrics, vol. 87, no. 9, 2020, pp. 745-747.
Rauf A, Vijayan A, John ST, et al. Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during COVID-19 Pandemic. Indian J Pediatr. 2020;87(9):745-747.
Rauf, A., Vijayan, A., John, S. T., Krishnan, R., & Latheef, A. (2020). Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during COVID-19 Pandemic. Indian Journal of Pediatrics, 87(9), 745-747. https://doi.org/10.1007/s12098-020-03357-1
Rauf A, et al. Multisystem Inflammatory Syndrome With Features of Atypical Kawasaki Disease During COVID-19 Pandemic. Indian J Pediatr. 2020;87(9):745-747. PubMed PMID: 32462354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during COVID-19 Pandemic. AU - Rauf,Abdul, AU - Vijayan,Ajay, AU - John,Shaji Thomas, AU - Krishnan,Raghuram, AU - Latheef,Abdul, Y1 - 2020/05/28/ PY - 2020/05/08/received PY - 2020/05/15/accepted PY - 2020/5/29/pubmed PY - 2020/5/29/medline PY - 2020/5/29/entrez KW - COVID-19 KW - Children KW - Inflammatory syndrome KW - Kawasaki disease KW - Multi-organ dysfunction SP - 745 EP - 747 JF - Indian journal of pediatrics JO - Indian J Pediatr VL - 87 IS - 9 N2 - There is a global concern of increasing number of children presenting with inflammatory syndrome with clinical features simulating Kawasaki disease, during ongoing COVID-19 pandemic. The authors report a very similar case of 5-y-old boy from a COVID-19 hotspot area who presented in late April 2020 with acute febrile illness with abdominal pain and loose stools followed by shock. On examination, child had bulbar conjunctivitis and extremity edema. Initial investigations showed high inflammatory parameters, elevated serum creatinine and liver enzymes. Echocardiography showed moderate LV dysfunction and normal coronaries. Cardiac enzymes were also elevated, suggesting myocarditis. He was treated with inotropic support, respiratory support with high flow nasal cannula, IV immunoglobulins, aspirin, steroids and diuretics. RT PCR for SARS-CoV-2 was negative twice. His clinical condition improved rapidly, was afebrile from day 2, inflammatory parameters decreased, left ventricular function improved and was discharged after 6 d of hospital stay. SN - 0973-7693 UR - https://www.unboundmedicine.com/medline/citation/32462354/Multisystem_Inflammatory_Syndrome_with_Features_of_Atypical_Kawasaki_Disease_during_COVID_19_Pandemic_ L2 - https://dx.doi.org/10.1007/s12098-020-03357-1 DB - PRIME DP - Unbound Medicine ER -