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SARS-CoV-2: The viral shedding vs infectivity dilemma.
Infect Dis Health. 2020 Aug; 25(3):210-215.ID

Abstract

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over four million people worldwide. There are multiple reports of prolonged viral shedding in people infected with SARS-CoV-2 but the presence of viral RNA on a test does not necessarily correlate with infectivity. The duration of quarantine required after clinical recovery to definitively prevent transmission is therefore uncertain. In addition, asymptomatic and presymptomatic transmission may occur, and infectivity may be highest early after onset of symptoms, meaning that contact tracing, isolation of exposed individuals and social distancing are essential public health measures to prevent further spread. This review aimed to summarise the evidence around viral shedding vs infectivity of SARS-CoV-2.

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Authors+Show Affiliations

Widders A
Department of Medicine, Sunshine Coast Hospital and Health Service, Birtinya, 4575, Queensland, Australia. Electronic address: arabella.widders@health.qld.gov.au.
Broom A
School of Social and Political Sciences, The University of Sydney, Sydney, 2006, New South Wales, Australia.
Broom J
Sunshine Coast Health Institute, Birtinya, 4575, Queensland, Australia; School of Medicine, The University of Queensland, Brisbane, 4072, Queensland, Australia.

MeSH

Asymptomatic InfectionsBetacoronavirusCOVID-19Coronavirus InfectionsHumansPandemicsPneumonia, ViralPublic HealthSARS-CoV-2Viral LoadVirus Shedding

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32473952

Citation

Widders, Arabella, et al. "SARS-CoV-2: the Viral Shedding Vs Infectivity Dilemma." Infection, Disease & Health, vol. 25, no. 3, 2020, pp. 210-215.
Widders A, Broom A, Broom J. SARS-CoV-2: The viral shedding vs infectivity dilemma. Infect Dis Health. 2020;25(3):210-215.
Widders, A., Broom, A., & Broom, J. (2020). SARS-CoV-2: The viral shedding vs infectivity dilemma. Infection, Disease & Health, 25(3), 210-215. https://doi.org/10.1016/j.idh.2020.05.002
Widders A, Broom A, Broom J. SARS-CoV-2: the Viral Shedding Vs Infectivity Dilemma. Infect Dis Health. 2020;25(3):210-215. PubMed PMID: 32473952.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SARS-CoV-2: The viral shedding vs infectivity dilemma. AU - Widders,Arabella, AU - Broom,Alex, AU - Broom,Jennifer, Y1 - 2020/05/20/ PY - 2020/4/29/received PY - 2020/5/13/revised PY - 2020/5/13/accepted PY - 2020/6/1/pubmed PY - 2020/8/5/medline PY - 2020/6/1/entrez KW - COVID-19 KW - Public health KW - SARS-CoV-2 KW - Transmission KW - Virus shedding SP - 210 EP - 215 JF - Infection, disease & health JO - Infect Dis Health VL - 25 IS - 3 N2 - Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over four million people worldwide. There are multiple reports of prolonged viral shedding in people infected with SARS-CoV-2 but the presence of viral RNA on a test does not necessarily correlate with infectivity. The duration of quarantine required after clinical recovery to definitively prevent transmission is therefore uncertain. In addition, asymptomatic and presymptomatic transmission may occur, and infectivity may be highest early after onset of symptoms, meaning that contact tracing, isolation of exposed individuals and social distancing are essential public health measures to prevent further spread. This review aimed to summarise the evidence around viral shedding vs infectivity of SARS-CoV-2. SN - 2468-0869 UR - https://www.unboundmedicine.com/medline/citation/32473952/SARS_CoV_2:_The_viral_shedding_vs_infectivity_dilemma_ DB - PRIME DP - Unbound Medicine ER -