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The impact of embryo binucleation depends upon its origin.
Reproduction. 2020 Jul; 160(1):V1-V4.R

Abstract

Summary

Preimplantation embryos frequently contain binucleated cells, but reports differ as to whether binucleation affects development and whether such embryos should be used clinically. In this Point Of View article, we propose a possible explanation for this disparity: binucleation can arise by distinct routes, one that produces healthy blastomeres and one that directly threatens embryo viability.

Authors+Show Affiliations

Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada. Département d'Obstétrique-Gynécologie, Université de Montréal, Montréal, Québec, Canada.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32484161

Citation

Gomes Paim, Lia Mara, and Greg FitzHarris. "The Impact of Embryo Binucleation Depends Upon Its Origin." Reproduction (Cambridge, England), vol. 160, no. 1, 2020, pp. V1-V4.
Gomes Paim LM, FitzHarris G. The impact of embryo binucleation depends upon its origin. Reproduction. 2020;160(1):V1-V4.
Gomes Paim, L. M., & FitzHarris, G. (2020). The impact of embryo binucleation depends upon its origin. Reproduction (Cambridge, England), 160(1), V1-V4. https://doi.org/10.1530/REP-20-0188
Gomes Paim LM, FitzHarris G. The Impact of Embryo Binucleation Depends Upon Its Origin. Reproduction. 2020;160(1):V1-V4. PubMed PMID: 32484161.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The impact of embryo binucleation depends upon its origin. AU - Gomes Paim,Lia Mara, AU - FitzHarris,Greg, PY - 2020/04/02/received PY - 2020/04/24/accepted PY - 2020/6/3/entrez SP - V1 EP - V4 JF - Reproduction (Cambridge, England) JO - Reproduction VL - 160 IS - 1 N2 - Summary: Preimplantation embryos frequently contain binucleated cells, but reports differ as to whether binucleation affects development and whether such embryos should be used clinically. In this Point Of View article, we propose a possible explanation for this disparity: binucleation can arise by distinct routes, one that produces healthy blastomeres and one that directly threatens embryo viability. SN - 1741-7899 UR - https://www.unboundmedicine.com/medline/citation/32484161/The_impact_of_embryo_binucleation_depends_upon_its_origin L2 - https://rep.bioscientifica.com/doi/10.1530/REP-20-0188 DB - PRIME DP - Unbound Medicine ER -
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