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Administration of rectal cytotec versus rectal buscopan before hysteroscopy.
Minim Invasive Ther Allied Technol. 2020 Jun 03 [Online ahead of print]MI

Abstract

Introduction: Our objective was to compare the effect of rectal misoprostol (Cytotec) versus rectal hyoscine-n-butyl bromide (Buscopan) on patients undergoing hysteroscopy. We hypothesised that HBB may have a role in cervical priming.Material and methods: This trial was conducted at Bezmialem Vakif University Hospital. Women of reproductive age between 18-50 years who were scheduled for operative hysteroscopy indicated by type 1 submucous myoma or endometrial polyps were recruited for the study. Ninety patients were divided randomly into three groups. Group 1 received placebo treatment. Group 2 received rectal 200 mcg misoprostol and Group 3 received rectal 20 mg hyoscine-n-butyl bromide two hours before the procedure. Procedures were performed using a bipolar 26 F (9 mm) continuous-flow rigid resectoscope with a 30° lens. The outcome measures included cervical dilation width and time, ease of cervical dilation, procedure time and operative complications. Postoperative self-rated pain was assessed one hour after the procedure.

Results:

Thirteen patients (43. 3%) in the placebo treatment group, 11 patients (36.7%) in the misoprostol group and four patients (13.3%) in the hyoscine-n-butyl bromide group needed analgesics postoperatively (p = .02). The mean duration of cervical dilation time was longest in Group 1 and shortest in Group 3, however this difference did not reach statistical significance (p=.11). There was no difference with regard to other studied parameters.

Summary:

HBB reduced the need for pain medication compared to placebo. Larger studies are needed to further investigate the role of HBB in facilitating pre-operative cervical priming.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Bezmialem Vakif University Medical Faculty, Istanbul, Turkey.Department of Obstetrics and Gynecology, Bezmialem Vakif University Medical Faculty, Istanbul, Turkey.Department of Obstetrics and Gynecology, Bezmialem Vakif University Medical Faculty, Istanbul, Turkey.Department of Obstetrics and Gynecology, Bezmialem Vakif University Medical Faculty, Istanbul, Turkey.Department of Gynecologic Oncology, Bakirkoy Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32491923

Citation

Gokmen Karasu, Ayse Filiz, et al. "Administration of Rectal Cytotec Versus Rectal Buscopan Before Hysteroscopy." Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy, 2020, pp. 1-5.
Gokmen Karasu AF, Aydin S, Ates S, et al. Administration of rectal cytotec versus rectal buscopan before hysteroscopy. Minim Invasive Ther Allied Technol. 2020.
Gokmen Karasu, A. F., Aydin, S., Ates, S., Takmaz, T., & Comba, C. (2020). Administration of rectal cytotec versus rectal buscopan before hysteroscopy. Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy, 1-5. https://doi.org/10.1080/13645706.2020.1748059
Gokmen Karasu AF, et al. Administration of Rectal Cytotec Versus Rectal Buscopan Before Hysteroscopy. Minim Invasive Ther Allied Technol. 2020 Jun 3;1-5. PubMed PMID: 32491923.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Administration of rectal cytotec versus rectal buscopan before hysteroscopy. AU - Gokmen Karasu,Ayse Filiz, AU - Aydin,Serdar, AU - Ates,Seda, AU - Takmaz,Taha, AU - Comba,Cihan, Y1 - 2020/06/03/ PY - 2020/6/4/entrez PY - 2020/6/4/pubmed PY - 2020/6/4/medline KW - Hysteroscopycervical priming pain hyoscine-n-butyl bromide KW - misoprostol SP - 1 EP - 5 JF - Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy JO - Minim Invasive Ther Allied Technol N2 - Introduction: Our objective was to compare the effect of rectal misoprostol (Cytotec) versus rectal hyoscine-n-butyl bromide (Buscopan) on patients undergoing hysteroscopy. We hypothesised that HBB may have a role in cervical priming.Material and methods: This trial was conducted at Bezmialem Vakif University Hospital. Women of reproductive age between 18-50 years who were scheduled for operative hysteroscopy indicated by type 1 submucous myoma or endometrial polyps were recruited for the study. Ninety patients were divided randomly into three groups. Group 1 received placebo treatment. Group 2 received rectal 200 mcg misoprostol and Group 3 received rectal 20 mg hyoscine-n-butyl bromide two hours before the procedure. Procedures were performed using a bipolar 26 F (9 mm) continuous-flow rigid resectoscope with a 30° lens. The outcome measures included cervical dilation width and time, ease of cervical dilation, procedure time and operative complications. Postoperative self-rated pain was assessed one hour after the procedure.Results: Thirteen patients (43. 3%) in the placebo treatment group, 11 patients (36.7%) in the misoprostol group and four patients (13.3%) in the hyoscine-n-butyl bromide group needed analgesics postoperatively (p = .02). The mean duration of cervical dilation time was longest in Group 1 and shortest in Group 3, however this difference did not reach statistical significance (p=.11). There was no difference with regard to other studied parameters.Summary: HBB reduced the need for pain medication compared to placebo. Larger studies are needed to further investigate the role of HBB in facilitating pre-operative cervical priming. SN - 1365-2931 UR - https://www.unboundmedicine.com/medline/citation/32491923/Administration_of_rectal_cytotec_versus_rectal_buscopan_before_hysteroscopy L2 - http://www.tandfonline.com/doi/full/10.1080/13645706.2020.1748059 DB - PRIME DP - Unbound Medicine ER -
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