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Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection?
J Med Virol. 2020 Jun 03 [Online ahead of print]JM

Abstract

"Retest Positive" for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) from "recovered" coronavirus disease-19 (COVID-19) has been reported and raised several important questions for this novel coronavirus and COVID-19 disease. In this commentary, we discussed several questions: (a) Can SARS-CoV-2 re-infect the individuals who recovered from COVID-19? This question is also associated with other questions: whether or not SARS-CoV-2 infection induces protective reaction or neutralized antibody? Will SARS-CoV-2 vaccines work? (b) Why could some recovered patients with COVID-19 be re-tested positive for SARS-CoV-2 RNA? (c) Are some recovered pwith atients COVID-19 with re-testing positive for SARS-CoV-2 RNA infectious? and (d) How should the COVID-19 patients with retest positive for SARS-CoV-2 be managed?

Authors+Show Affiliations

Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.Departments of Pathology and Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32492212

Citation

Kang, Hanyujie, et al. "Retest Positive for SARS-CoV-2 RNA of "recovered" Patients With COVID-19: Persistence, Sampling Issues, or Re-infection?" Journal of Medical Virology, 2020.
Kang H, Wang Y, Tong Z, et al. Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection? J Med Virol. 2020.
Kang, H., Wang, Y., Tong, Z., & Liu, X. (2020). Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection? Journal of Medical Virology. https://doi.org/10.1002/jmv.26114
Kang H, et al. Retest Positive for SARS-CoV-2 RNA of "recovered" Patients With COVID-19: Persistence, Sampling Issues, or Re-infection. J Med Virol. 2020 Jun 3; PubMed PMID: 32492212.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection? AU - Kang,Hanyujie, AU - Wang,Yishan, AU - Tong,Zhaohui, AU - Liu,Xuefeng, Y1 - 2020/06/03/ PY - 2020/05/18/received PY - 2020/05/28/revised PY - 2020/05/29/accepted PY - 2020/6/4/pubmed PY - 2020/6/4/medline PY - 2020/6/4/entrez KW - SARS coronavirus < virus classification KW - coronavirus < virus classification KW - disease control KW - immunity/immunization < epidemiology KW - persistent infection < infection JF - Journal of medical virology JO - J. Med. Virol. N2 - "Retest Positive" for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) from "recovered" coronavirus disease-19 (COVID-19) has been reported and raised several important questions for this novel coronavirus and COVID-19 disease. In this commentary, we discussed several questions: (a) Can SARS-CoV-2 re-infect the individuals who recovered from COVID-19? This question is also associated with other questions: whether or not SARS-CoV-2 infection induces protective reaction or neutralized antibody? Will SARS-CoV-2 vaccines work? (b) Why could some recovered patients with COVID-19 be re-tested positive for SARS-CoV-2 RNA? (c) Are some recovered pwith atients COVID-19 with re-testing positive for SARS-CoV-2 RNA infectious? and (d) How should the COVID-19 patients with retest positive for SARS-CoV-2 be managed? SN - 1096-9071 UR - https://www.unboundmedicine.com/medline/citation/32492212/Retest_positive_for_SARS_CoV_2_RNA_of_"recovered"_patients_with_COVID_19:_Persistence_sampling_issues_or_re_infection L2 - https://doi.org/10.1002/jmv.26114 DB - PRIME DP - Unbound Medicine ER -
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