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Outcome of upper respiratory tract infections in healthy children: Antibiotic stewardship in treatment of acute upper respiratory tract infections.
Pak J Med Sci. 2020 May-Jun; 36(4):642-646.PJ

Abstract

Objective

The objective of the study was to assess the outcome of upper respiratory tract infections (URTI) in healthy children.

Methods

This descriptive study was conducted on 314 children aged 3-36 months in the paediatric outpatient clinic and emergency department with symptoms of URTI (fever, cough, rhinorrhoea) for ≤5 days. Patient's demographics, clinical features, laboratory data and outcome were recorded. Follow up phone calls were made to parents on day 7 (response 93.6%) and day 14 (response 94.6%) to record outcome.

Results

A total of 314 children with URTIs were included. Majority (57.6%) were males and <1year of age (40%). Common manifestations of URTI were fever (89%), cough (79%), rhinorrhoea (62%), pharyngitis (79%) and conjunctivitis (46%). More than half (53%) had history of contact with URTI in a family member. Mean duration of symptoms was 2.7±1.3 days. Majority (93%) of children were given supportive treatment and only 6.7% received antibiotics initially. Most of children (76%) recovered within one week and 91.8% within two weeks with supportive care only. Only 4% children were hospitalized and 12% required follow up visit of which 16% needed oral antibiotics. Complications or deaths did not occur.

Conclusions

Majority of URTIs in healthy children resolved with supportive treatment and do not require antibiotics. Antibiotic stewardship in simple URTIs should be practiced using awareness and advocacy campaigns.

Authors+Show Affiliations

Ejaz Ahmed Khan, MBBS, MD. Department of Pediatrics, Shifa International Hospital Ltd, Shifa Tameer-e-Millat University, Islamabad, Pakistan.Mazhar Hussain Raja, MRCP, MRCPC. Department of Pediatrics, Shifa International Hospital Ltd, Shifa Tameer-e-Millat University, Islamabad, Pakistan.Shehla Chaudhry, FCPS. Department of Pediatrics, Shifa International Hospital Ltd, Shifa Tameer-e-Millat University, Islamabad, Pakistan.Tehreem Zahra, MBBS. Department of Pediatrics, Shifa International Hospital Ltd, Shifa Tameer-e-Millat University, Islamabad, Pakistan.Salman Naeem, MBBS. Department of Emergency Medicine, Shifa International Hospital Ltd, Shifa Tameer-e-Millat University, Islamabad, Pakistan.Masuma Anwar, MBBS. Department of Pediatrics, Shifa International Hospital Ltd, Shifa Tameer-e-Millat University, Islamabad, Pakistan.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32494248

Citation

Khan, Ejaz Ahmed, et al. "Outcome of Upper Respiratory Tract Infections in Healthy Children: Antibiotic Stewardship in Treatment of Acute Upper Respiratory Tract Infections." Pakistan Journal of Medical Sciences, vol. 36, no. 4, 2020, pp. 642-646.
Khan EA, Raja MH, Chaudhry S, et al. Outcome of upper respiratory tract infections in healthy children: Antibiotic stewardship in treatment of acute upper respiratory tract infections. Pakistan journal of medical sciences. 2020;36(4):642-646.
Khan, E. A., Raja, M. H., Chaudhry, S., Zahra, T., Naeem, S., & Anwar, M. (2020). Outcome of upper respiratory tract infections in healthy children: Antibiotic stewardship in treatment of acute upper respiratory tract infections. Pakistan Journal of Medical Sciences, 36(4), 642-646. https://doi.org/10.12669/pjms.36.4.1420
Khan EA, et al. Outcome of Upper Respiratory Tract Infections in Healthy Children: Antibiotic Stewardship in Treatment of Acute Upper Respiratory Tract Infections. Pakistan journal of medical sciences. 2020 May-Jun;36(4):642-646. PubMed PMID: 32494248.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcome of upper respiratory tract infections in healthy children: Antibiotic stewardship in treatment of acute upper respiratory tract infections. AU - Khan,Ejaz Ahmed, AU - Raja,Mazhar Hussain, AU - Chaudhry,Shehla, AU - Zahra,Tehreem, AU - Naeem,Salman, AU - Anwar,Masuma, PY - 2020/6/5/entrez PY - 2020/6/5/pubmed PY - 2020/6/5/medline KW - Antibiotic stewardship KW - Antibiotics KW - Children KW - Upper respiratory tract infections SP - 642 EP - 646 JF - Pakistan journal of medical sciences VL - 36 IS - 4 N2 - Objective: The objective of the study was to assess the outcome of upper respiratory tract infections (URTI) in healthy children. Methods: This descriptive study was conducted on 314 children aged 3-36 months in the paediatric outpatient clinic and emergency department with symptoms of URTI (fever, cough, rhinorrhoea) for ≤5 days. Patient's demographics, clinical features, laboratory data and outcome were recorded. Follow up phone calls were made to parents on day 7 (response 93.6%) and day 14 (response 94.6%) to record outcome. Results: A total of 314 children with URTIs were included. Majority (57.6%) were males and <1year of age (40%). Common manifestations of URTI were fever (89%), cough (79%), rhinorrhoea (62%), pharyngitis (79%) and conjunctivitis (46%). More than half (53%) had history of contact with URTI in a family member. Mean duration of symptoms was 2.7±1.3 days. Majority (93%) of children were given supportive treatment and only 6.7% received antibiotics initially. Most of children (76%) recovered within one week and 91.8% within two weeks with supportive care only. Only 4% children were hospitalized and 12% required follow up visit of which 16% needed oral antibiotics. Complications or deaths did not occur. Conclusions: Majority of URTIs in healthy children resolved with supportive treatment and do not require antibiotics. Antibiotic stewardship in simple URTIs should be practiced using awareness and advocacy campaigns. SN - 1682-024X UR - https://www.unboundmedicine.com/medline/citation/32494248/Outcome_of_upper_respiratory_tract_infections_in_healthy_children:_Antibiotic_stewardship_in_treatment_of_acute_upper_respiratory_tract_infections_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32494248/ DB - PRIME DP - Unbound Medicine ER -
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