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Comprehensive Evidence-Based Guidelines for Facet Joint Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines Facet Joint Interventions 2020 Guidelines.
Pain Physician. 2020 05; 23(3S):S1-S127.PP

Abstract

BACKGROUND

Chronic axial spinal pain is one of the major causes of significant disability and health care costs, with facet joints as one of the proven causes of pain.

OBJECTIVE

To provide evidence-based guidance in performing diagnostic and therapeutic facet joint interventions.

METHODS

The methodology utilized included the development of objectives and key questions with utilization of trustworthy standards. The literature pertaining to all aspects of facet joint interventions, was reviewed, with a best evidence synthesis of available literature and utilizing grading for recommendations.Summary of Evidence and Recommendations:Non-interventional diagnosis: • The level of evidence is II in selecting patients for facet joint nerve blocks at least 3 months after onset and failure of conservative management, with strong strength of recommendation for physical examination and clinical assessment. • The level of evidence is IV for accurate diagnosis of facet joint pain with physical examination based on symptoms and signs, with weak strength of recommendation. Imaging: • The level of evidence is I with strong strength of recommendation, for mandatory fluoroscopic or computed tomography (CT) guidance for all facet joint interventions. • The level of evidence is III with weak strength of recommendation for single photon emission computed tomography (SPECT) . • The level of evidence is V with weak strength of recommendation for scintography, magnetic resonance imaging (MRI), and computed tomography (CT) .Interventional Diagnosis:Lumbar Spine: • The level of evidence is I to II with moderate to strong strength of recommendation for lumbar diagnostic facet joint nerve blocks. • Ten relevant diagnostic accuracy studies with 4 of 10 studies utilizing controlled comparative local anesthetics with concordant pain relief criterion standard of ≥80% were included. • The prevalence rates ranged from 27% to 40% with false-positive rates of 27% to 47%, with ≥80% pain relief.Cervical Spine: • The level of evidence is II with moderate strength of recommendation. • Ten relevant diagnostic accuracy studies, 9 of the 10 studies with either controlled comparative local anesthetic blocks or placebo controls with concordant pain relief with a criterion standard of ≥80% were included. • The prevalence and false-positive rates ranged from 29% to 60% and of 27% to 63%, with high variability. Thoracic Spine: • The level of evidence is II with moderate strength of recommendation. • Three relevant diagnostic accuracy studies, with controlled comparative local anesthetic blocks, with concordant pain relief, with a criterion standard of ≥80% were included. • The prevalence varied from 34% to 48%, whereas false-positive rates varied from 42% to 58%.Therapeutic Facet Joint Interventions: Lumbar Spine: • The level of evidence is II with moderate strength of recommendation for lumbar radiofrequency ablation with inclusion of 11 relevant randomized controlled trials (RCTs) with 2 negative studies and 4 studies with long-term improvement. • The level of evidence is II with moderate strength of recommendation for therapeutic lumbar facet joint nerve blocks with inclusion of 3 relevant randomized controlled trials, with long-term improvement. • The level of evidence is IV with weak strength of recommendation for lumbar facet joint intraarticular injections with inclusion of 9 relevant randomized controlled trials, with majority of them showing lack of effectiveness without the use of local anesthetic. Cervical Spine: • The level of evidence is II with moderate strength of recommendation for cervical radiofrequency ablation with inclusion of one randomized controlled trial with positive results and 2 observational studies with long-term improvement. • The level of evidence is II with moderate strength of recommendation for therapeutic cervical facet joint nerve blocks with inclusion of one relevant randomized controlled trial and 3 observational studies, with long-term improvement. • The level of evidence is V with weak strength of recommendation for cervical intraarticular facet joint injections with inclusion of 3 relevant randomized controlled trials, with 2 observational studies, the majority showing lack of effectiveness, whereas one study with 6-month follow-up, showed lack of long-term improvement. Thoracic Spine: • The level of evidence is III with weak to moderate strength of recommendation with emerging evidence for thoracic radiofrequency ablation with inclusion of one relevant randomized controlled trial and 3 observational studies. • The level of evidence is II with moderate strength of recommendation for thoracic therapeutic facet joint nerve blocks with inclusion of 2 randomized controlled trials and one observational study with long-term improvement. • The level of evidence is III with weak to moderate strength of recommendation for thoracic intraarticular facet joint injections with inclusion of one randomized controlled trial with 6 month follow-up, with emerging evidence. Antithrombotic Therapy: • Facet joint interventions are considered as moderate to low risk procedures; consequently, antithrombotic therapy may be continued based on overall general status. Sedation: • The level of evidence is II with moderate strength of recommendation to avoid opioid analgesics during the diagnosis with interventional techniques. • The level of evidence is II with moderate strength of recommendation that moderate sedation may be utilized for patient comfort and to control anxiety for therapeutic facet joint interventions.

LIMITATIONS

The limitations of these guidelines include a paucity of high-quality studies in the majority of aspects of diagnosis and therapy.

CONCLUSIONS

These facet joint intervention guidelines were prepared with a comprehensive review of the literature with methodologic quality assessment with determination of level of evidence and strength of recommendations.

KEY WORDS

Chronic spinal pain, interventional techniques, diagnostic blocks, therapeutic interventions, facet joint nerve blocks, intraarticular injections, radiofrequency neurolysis.

Authors+Show Affiliations

Pain Management Centers of America, Paducah, KY and Evansville, IN; LSU Health Science Center, New Orleans, LA.LSU Health Science Center, New Orleans.Ohio Pain Clinic.Radiology Research and Consultation.Clinical Radiology of Oklahoma, Edmond, OK.Radiology Research and Consultation.Pain Management Centers of America, Evansville, IN.No affiliation info availableTri State Spine Care Institute.Department of Anesthesiology University of Wisconsin, School of Medicine and Public Health, Madison, WI.University of Texas, MD Anderson Cancer Center, Houston, TX.Manhattan Spine and Pain Medicine, New York, NY, and Hofstra-North Shore/LIJ School of Medicine, New York, NY.SurgiCare of Manhattan and Lenox Hill Hospital.Department of Anesthesiology and Perioperative Medicine, University of Louisville.Pain Relief of Dayton, Centerville, OH, and Clinical Associate Professor, Department of Surgery, Wright State University School of Medicine, Dayton, OH.Genesis Pain Specialist.Precision Spine Care, Tyler, TX.Department of Anesthesiology, Advocate Illinois Masonic Medical Center and Professor of Clinical Surgery and Anesthesia, University of Illinois College of Medicine.Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Blaustein Pain Treatment Center, Johns Hopkins Hospital, Baltimore MD.Dept. of Anesthesiology and Perioperative Care, Adjunct Associate Clinical Professor, University of California, Irvine School of Medicine, Irvine, CA.Advanced Spine on Park Avenue.Department of Anesthesiology, Perioperative Care and Pain Medicine, New York University Langone Health, New York, NY.Departments of Anesthesiology, University of Kentucky, Chandler Medical Center, Lexington, KY.Kansas Pain Management & Neuroscience Research Center, LLC, Overland Park, KS, and Adjunct Clinical Assistant Professor, Anesthesiology and Pain Medicine, Kansas City University of Medicine and Biosciences, Kansas City, MO.Pain Management Centers of America, Louisville, KY.Departments of Anesthesiology, University of Kentucky, Chandler Medical Center, Lexington, KY.The Helm Center for Pain Management.Axis Spine Center, Coeur d'Alene, ID.No affiliation info availableNo affiliation info availableVice Chair for Research and Education, Department of Anesthesiology and Pain Management, Advocate Illinois Masonic Medical Center, Clinical Associate Professor of Anesthesiology and Surgery at University of Illinois, Chicago, IL.Pain Management Centers of America.University of Kentucky, Lexington KY.Comprehensive Pain Management Center, Campbell, CA.No affiliation info availablePain Management Centers of America, Paducah, KY.Center for Pain Management.Advocate Illinois Masonic Medical Center.Sutter Gould Medical Foundation, Stockton, CA.No affiliation info availableCincinnati Pain Management Consultants, Cincinnati, OH.Oregon Health and Science University, Portland, OR.Department of Interventional and Non-Interventional Pain Management, OrthoSouth Surgery Center.Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Pub Type(s)

Journal Article
Practice Guideline

Language

eng

PubMed ID

32503359

Citation

Manchikanti, Laxmaiah, et al. "Comprehensive Evidence-Based Guidelines for Facet Joint Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines Facet Joint Interventions 2020 Guidelines." Pain Physician, vol. 23, no. 3S, 2020, pp. S1-S127.
Manchikanti L, Kaye AD, Soin A, et al. Comprehensive Evidence-Based Guidelines for Facet Joint Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines Facet Joint Interventions 2020 Guidelines. Pain Physician. 2020;23(3S):S1-S127.
Manchikanti, L., Kaye, A. D., Soin, A., Albers, S. L., Beall, D., Latchaw, R., Sanapati, M. R., Shah, S., Atluri, S., Abd-Elsayed, A., Abdi, S., Aydin, S., Bakshi, S., Boswell, M. V., Buenaventura, R., Cabaret, J., Calodney, A. K., Candido, K. D., Christo, P. J., ... Hirsch, J. A. (2020). Comprehensive Evidence-Based Guidelines for Facet Joint Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines Facet Joint Interventions 2020 Guidelines. Pain Physician, 23(3S), S1-S127.
Manchikanti L, et al. Comprehensive Evidence-Based Guidelines for Facet Joint Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines Facet Joint Interventions 2020 Guidelines. Pain Physician. 2020;23(3S):S1-S127. PubMed PMID: 32503359.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comprehensive Evidence-Based Guidelines for Facet Joint Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines Facet Joint Interventions 2020 Guidelines. AU - Manchikanti,Laxmaiah, AU - Kaye,Alan D, AU - Soin,Amol, AU - Albers,Sheri L, AU - Beall,Douglas, AU - Latchaw,Richard, AU - Sanapati,Mahendra R, AU - Shah,Shalini, AU - Atluri,Sairam, AU - Abd-Elsayed,Alaa, AU - Abdi,Salahadin, AU - Aydin,Steve, AU - Bakshi,Sanjay, AU - Boswell,Mark V, AU - Buenaventura,Ricardo, AU - Cabaret,Joseph, AU - Calodney,Aaron K, AU - Candido,Kenneth D, AU - Christo,Paul J, AU - Cintron,Lynn, AU - Diwan,Sudhir, AU - Gharibo,Christopher, AU - Grider,Jay, AU - Gupta,Mayank, AU - Haney,Bill, AU - Harned,Michael E, AU - Helm Ii,Standiford, AU - Jameson,Jessica, AU - Jha,Sunny, AU - Kaye,Adam M, AU - Knezevic,Nebojsa Nick, AU - Kosanovic,Radomir, AU - Manchikanti,Maanasa V, AU - Navani,Annu, AU - Racz,Gabor, AU - Pampati,Vidyasagar, AU - Pasupuleti,Ramarao, AU - Philip,Cyril, AU - Rajput,Kartic, AU - Sehgal,Nalini, AU - Sudarshan,Gururau, AU - Vanaparthy,Rachana, AU - Wargo,Bradley W, AU - Hirsch,Joshua A, PY - 2020/6/7/entrez PY - 2020/6/7/pubmed PY - 2020/9/1/medline SP - S1 EP - S127 JF - Pain physician JO - Pain Physician VL - 23 IS - 3S N2 - BACKGROUND: Chronic axial spinal pain is one of the major causes of significant disability and health care costs, with facet joints as one of the proven causes of pain. OBJECTIVE: To provide evidence-based guidance in performing diagnostic and therapeutic facet joint interventions. METHODS: The methodology utilized included the development of objectives and key questions with utilization of trustworthy standards. The literature pertaining to all aspects of facet joint interventions, was reviewed, with a best evidence synthesis of available literature and utilizing grading for recommendations.Summary of Evidence and Recommendations:Non-interventional diagnosis: • The level of evidence is II in selecting patients for facet joint nerve blocks at least 3 months after onset and failure of conservative management, with strong strength of recommendation for physical examination and clinical assessment. • The level of evidence is IV for accurate diagnosis of facet joint pain with physical examination based on symptoms and signs, with weak strength of recommendation. Imaging: • The level of evidence is I with strong strength of recommendation, for mandatory fluoroscopic or computed tomography (CT) guidance for all facet joint interventions. • The level of evidence is III with weak strength of recommendation for single photon emission computed tomography (SPECT) . • The level of evidence is V with weak strength of recommendation for scintography, magnetic resonance imaging (MRI), and computed tomography (CT) .Interventional Diagnosis:Lumbar Spine: • The level of evidence is I to II with moderate to strong strength of recommendation for lumbar diagnostic facet joint nerve blocks. • Ten relevant diagnostic accuracy studies with 4 of 10 studies utilizing controlled comparative local anesthetics with concordant pain relief criterion standard of ≥80% were included. • The prevalence rates ranged from 27% to 40% with false-positive rates of 27% to 47%, with ≥80% pain relief.Cervical Spine: • The level of evidence is II with moderate strength of recommendation. • Ten relevant diagnostic accuracy studies, 9 of the 10 studies with either controlled comparative local anesthetic blocks or placebo controls with concordant pain relief with a criterion standard of ≥80% were included. • The prevalence and false-positive rates ranged from 29% to 60% and of 27% to 63%, with high variability. Thoracic Spine: • The level of evidence is II with moderate strength of recommendation. • Three relevant diagnostic accuracy studies, with controlled comparative local anesthetic blocks, with concordant pain relief, with a criterion standard of ≥80% were included. • The prevalence varied from 34% to 48%, whereas false-positive rates varied from 42% to 58%.Therapeutic Facet Joint Interventions: Lumbar Spine: • The level of evidence is II with moderate strength of recommendation for lumbar radiofrequency ablation with inclusion of 11 relevant randomized controlled trials (RCTs) with 2 negative studies and 4 studies with long-term improvement. • The level of evidence is II with moderate strength of recommendation for therapeutic lumbar facet joint nerve blocks with inclusion of 3 relevant randomized controlled trials, with long-term improvement. • The level of evidence is IV with weak strength of recommendation for lumbar facet joint intraarticular injections with inclusion of 9 relevant randomized controlled trials, with majority of them showing lack of effectiveness without the use of local anesthetic. Cervical Spine: • The level of evidence is II with moderate strength of recommendation for cervical radiofrequency ablation with inclusion of one randomized controlled trial with positive results and 2 observational studies with long-term improvement. • The level of evidence is II with moderate strength of recommendation for therapeutic cervical facet joint nerve blocks with inclusion of one relevant randomized controlled trial and 3 observational studies, with long-term improvement. • The level of evidence is V with weak strength of recommendation for cervical intraarticular facet joint injections with inclusion of 3 relevant randomized controlled trials, with 2 observational studies, the majority showing lack of effectiveness, whereas one study with 6-month follow-up, showed lack of long-term improvement. Thoracic Spine: • The level of evidence is III with weak to moderate strength of recommendation with emerging evidence for thoracic radiofrequency ablation with inclusion of one relevant randomized controlled trial and 3 observational studies. • The level of evidence is II with moderate strength of recommendation for thoracic therapeutic facet joint nerve blocks with inclusion of 2 randomized controlled trials and one observational study with long-term improvement. • The level of evidence is III with weak to moderate strength of recommendation for thoracic intraarticular facet joint injections with inclusion of one randomized controlled trial with 6 month follow-up, with emerging evidence. Antithrombotic Therapy: • Facet joint interventions are considered as moderate to low risk procedures; consequently, antithrombotic therapy may be continued based on overall general status. Sedation: • The level of evidence is II with moderate strength of recommendation to avoid opioid analgesics during the diagnosis with interventional techniques. • The level of evidence is II with moderate strength of recommendation that moderate sedation may be utilized for patient comfort and to control anxiety for therapeutic facet joint interventions. LIMITATIONS: The limitations of these guidelines include a paucity of high-quality studies in the majority of aspects of diagnosis and therapy. CONCLUSIONS: These facet joint intervention guidelines were prepared with a comprehensive review of the literature with methodologic quality assessment with determination of level of evidence and strength of recommendations. KEY WORDS: Chronic spinal pain, interventional techniques, diagnostic blocks, therapeutic interventions, facet joint nerve blocks, intraarticular injections, radiofrequency neurolysis. SN - 2150-1149 UR - https://www.unboundmedicine.com/medline/citation/32503359/Comprehensive_Evidence_Based_Guidelines_for_Facet_Joint_Interventions_in_the_Management_of_Chronic_Spinal_Pain:_American_Society_of_Interventional_Pain_Physicians__ASIPP__Guidelines_Facet_Joint_Interventions_2020_Guidelines_ L2 - http://www.painphysicianjournal.com/linkout?issn=1533-3159&vol=23&page=S1 DB - PRIME DP - Unbound Medicine ER -