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Clinical characteristics of coronavirus disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases.
Dig Liver Dis. 2020 10; 52(10):1076-1079.DL

Abstract

Objective

To explore the clinical characteristics of Coronavirus Disease (COVID-19) patients with gastrointestinal symptoms.

Methods

The clinical data of 164 COVID-19 patients with gastrointestinal symptoms were extracted and analysed retrospectively.

Results

In total, 505 COVID-19 patients were divided into two groups: those with gastrointestinal symptoms (G group) and those without gastrointestinal symptoms (NG group). Common gastrointestinal symptoms included inappetence, diarrhoea, nausea, abdominal pain, and vomiting. Significantly higher proportions of patients with fever, dizziness, myalgia, and fatigue were noted in group G than in group NG. Compared with patients without fever, there was a significant difference between G group and NG group in moderate fever or above, while there was no significant difference between the two groups in low fever. The laboratory results showed that patients in the G group had significantly higher C-reactive protein, lactate dehydrogenase, and α-hydroxybutyrate dehydrogenase levels than those in the NG group. Moreover, the proportion of patients with severe pneumonia was significantly higher in the G group than in the NG group.

Conclusion

In Wuhan, the proportion of COVID-19 patients who experience gastrointestinal symptoms is relatively high. Patients who experience gastrointestinal symptoms are more likely to suffer from severe pneumonia, which may help clinicians identify patients at high risk of COVID-19 and thus reduce the incidence of this condition.

Authors+Show Affiliations

Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China.Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China.Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China.Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China.Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China.Department of Gastroenterology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, 26 Shengli Street, Jiang'an District, Wuhan 430014, China. Electronic address: 497697662@qq.com.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

32507692

Citation

Zhang, Hu, et al. "Clinical Characteristics of Coronavirus Disease (COVID-19) Patients With Gastrointestinal Symptoms: a Report of 164 Cases." Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 52, no. 10, 2020, pp. 1076-1079.
Zhang H, Liao YS, Gong J, et al. Clinical characteristics of coronavirus disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases. Dig Liver Dis. 2020;52(10):1076-1079.
Zhang, H., Liao, Y. S., Gong, J., Liu, J., Xia, X., & Zhang, H. (2020). Clinical characteristics of coronavirus disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 52(10), 1076-1079. https://doi.org/10.1016/j.dld.2020.04.034
Zhang H, et al. Clinical Characteristics of Coronavirus Disease (COVID-19) Patients With Gastrointestinal Symptoms: a Report of 164 Cases. Dig Liver Dis. 2020;52(10):1076-1079. PubMed PMID: 32507692.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical characteristics of coronavirus disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases. AU - Zhang,Hu, AU - Liao,Yu-Sheng, AU - Gong,Jing, AU - Liu,Jing, AU - Xia,Xi, AU - Zhang,Heng, Y1 - 2020/05/08/ PY - 2020/04/10/received PY - 2020/04/26/revised PY - 2020/04/28/accepted PY - 2020/6/9/pubmed PY - 2020/10/6/medline PY - 2020/6/9/entrez KW - COVID-19 KW - Gastrointestinal symptoms KW - Novel coronavirus KW - Novel coronavirus pneumonia KW - SARS-CoV-2 SP - 1076 EP - 1079 JF - Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver JO - Dig Liver Dis VL - 52 IS - 10 N2 - Objective: To explore the clinical characteristics of Coronavirus Disease (COVID-19) patients with gastrointestinal symptoms. Methods: The clinical data of 164 COVID-19 patients with gastrointestinal symptoms were extracted and analysed retrospectively. Results: In total, 505 COVID-19 patients were divided into two groups: those with gastrointestinal symptoms (G group) and those without gastrointestinal symptoms (NG group). Common gastrointestinal symptoms included inappetence, diarrhoea, nausea, abdominal pain, and vomiting. Significantly higher proportions of patients with fever, dizziness, myalgia, and fatigue were noted in group G than in group NG. Compared with patients without fever, there was a significant difference between G group and NG group in moderate fever or above, while there was no significant difference between the two groups in low fever. The laboratory results showed that patients in the G group had significantly higher C-reactive protein, lactate dehydrogenase, and α-hydroxybutyrate dehydrogenase levels than those in the NG group. Moreover, the proportion of patients with severe pneumonia was significantly higher in the G group than in the NG group. Conclusion: In Wuhan, the proportion of COVID-19 patients who experience gastrointestinal symptoms is relatively high. Patients who experience gastrointestinal symptoms are more likely to suffer from severe pneumonia, which may help clinicians identify patients at high risk of COVID-19 and thus reduce the incidence of this condition. SN - 1878-3562 UR - https://www.unboundmedicine.com/medline/citation/32507692/Clinical_characteristics_of_coronavirus_disease__COVID_19__patients_with_gastrointestinal_symptoms:_A_report_of_164_cases_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1590-8658(20)30189-4 DB - PRIME DP - Unbound Medicine ER -