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A rapid systematic review of the efficacy of face masks and respirators against coronaviruses and other respiratory transmissible viruses for the community, healthcare workers and sick patients.
Int J Nurs Stud. 2020 Aug; 108:103629.IJ

Abstract

BACKGROUND

The pandemic of COVID-19 is growing, and a shortage of masks and respirators has been reported globally. Policies of health organizations for healthcare workers are inconsistent, with a change in policy in the US for universal face mask use. The aim of this study was to review the evidence around the efficacy of masks and respirators for healthcare workers, sick patients and the general public.

METHODS

A systematic review of randomized controlled clinical trials on use of respiratory protection by healthcare workers, sick patients and community members was conducted. Articles were searched on Medline and Embase using key search terms.

RESULTS

A total of 19 randomised controlled trials were included in this study - 8 in community settings, 6 in healthcare settings and 5 as source control. Most of these randomised controlled trials used different interventions and outcome measures. In the community, masks appeared to be effective with and without hand hygiene, and both together are more protective. Randomised controlled trials in health care workers showed that respirators, if worn continually during a shift, were effective but not if worn intermittently. Medical masks were not effective, and cloth masks even less effective. When used by sick patients randomised controlled trials suggested protection of well contacts.

CONCLUSION

The study suggests that community mask use by well people could be beneficial, particularly for COVID-19, where transmission may be pre-symptomatic. The studies of masks as source control also suggest a benefit, and may be important during the COVID-19 pandemic in universal community face mask use as well as in health care settings. Trials in healthcare workers support the use of respirators continuously during a shift. This may prevent health worker infections and deaths from COVID-19, as aerosolisation in the hospital setting has been documented.

Authors+Show Affiliations

The Kirby Institute, UNSW Medicine, University of New South Wales, Sydney, Australia. Electronic address: r.macintyre@unsw.edu.au.School of Public Health and Community Medicine, UNSW Medicine, University of New South Wales, Room 228, Level 2 Samuels Building, Sydney, Australia. Electronic address: abrar.chughtai@unsw.edu.au.

Pub Type(s)

Journal Article
Systematic Review

Language

eng

PubMed ID

32512240

Citation

MacIntyre, C Raina, and Abrar Ahmad Chughtai. "A Rapid Systematic Review of the Efficacy of Face Masks and Respirators Against Coronaviruses and Other Respiratory Transmissible Viruses for the Community, Healthcare Workers and Sick Patients." International Journal of Nursing Studies, vol. 108, 2020, p. 103629.
MacIntyre CR, Chughtai AA. A rapid systematic review of the efficacy of face masks and respirators against coronaviruses and other respiratory transmissible viruses for the community, healthcare workers and sick patients. Int J Nurs Stud. 2020;108:103629.
MacIntyre, C. R., & Chughtai, A. A. (2020). A rapid systematic review of the efficacy of face masks and respirators against coronaviruses and other respiratory transmissible viruses for the community, healthcare workers and sick patients. International Journal of Nursing Studies, 108, 103629. https://doi.org/10.1016/j.ijnurstu.2020.103629
MacIntyre CR, Chughtai AA. A Rapid Systematic Review of the Efficacy of Face Masks and Respirators Against Coronaviruses and Other Respiratory Transmissible Viruses for the Community, Healthcare Workers and Sick Patients. Int J Nurs Stud. 2020;108:103629. PubMed PMID: 32512240.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A rapid systematic review of the efficacy of face masks and respirators against coronaviruses and other respiratory transmissible viruses for the community, healthcare workers and sick patients. AU - MacIntyre,C Raina, AU - Chughtai,Abrar Ahmad, Y1 - 2020/04/30/ PY - 2020/03/24/received PY - 2020/04/18/revised PY - 2020/04/21/accepted PY - 2020/6/9/pubmed PY - 2020/7/9/medline PY - 2020/6/9/entrez KW - COVID19 KW - Coronavirus KW - Coronavirus disease KW - Mask KW - Personal protective equipment KW - Respirators SP - 103629 EP - 103629 JF - International journal of nursing studies JO - Int J Nurs Stud VL - 108 N2 - BACKGROUND: The pandemic of COVID-19 is growing, and a shortage of masks and respirators has been reported globally. Policies of health organizations for healthcare workers are inconsistent, with a change in policy in the US for universal face mask use. The aim of this study was to review the evidence around the efficacy of masks and respirators for healthcare workers, sick patients and the general public. METHODS: A systematic review of randomized controlled clinical trials on use of respiratory protection by healthcare workers, sick patients and community members was conducted. Articles were searched on Medline and Embase using key search terms. RESULTS: A total of 19 randomised controlled trials were included in this study - 8 in community settings, 6 in healthcare settings and 5 as source control. Most of these randomised controlled trials used different interventions and outcome measures. In the community, masks appeared to be effective with and without hand hygiene, and both together are more protective. Randomised controlled trials in health care workers showed that respirators, if worn continually during a shift, were effective but not if worn intermittently. Medical masks were not effective, and cloth masks even less effective. When used by sick patients randomised controlled trials suggested protection of well contacts. CONCLUSION: The study suggests that community mask use by well people could be beneficial, particularly for COVID-19, where transmission may be pre-symptomatic. The studies of masks as source control also suggest a benefit, and may be important during the COVID-19 pandemic in universal community face mask use as well as in health care settings. Trials in healthcare workers support the use of respirators continuously during a shift. This may prevent health worker infections and deaths from COVID-19, as aerosolisation in the hospital setting has been documented. SN - 1873-491X UR - https://www.unboundmedicine.com/medline/citation/32512240/A_rapid_systematic_review_of_the_efficacy_of_face_masks_and_respirators_against_coronaviruses_and_other_respiratory_transmissible_viruses_for_the_community_healthcare_workers_and_sick_patients_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0020-7489(20)30113-9 DB - PRIME DP - Unbound Medicine ER -