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Neurological manifestations of COVID-19.
J Pak Med Assoc. 2020 May; 70(Suppl 3)(5):S101-S103.JP

Abstract

Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has turned out to be a formidable pandemic. Upcoming evidence from confirmed cases of COVID-19 suggests an anticipated incursion of patients with neurological manifestations in the weeks to come. An expression of the angiotensin-converting enzyme 2 (ACE 2), the cellular receptor for SARS-CoV-2 over the glial cells and neurons have made the brain a potential target. Neurotoxicity may occur as a result of direct, indirect and post-infectious complications. Attention to neurological deficits in COVID-19 is fundamental to ensure appropriate, timely, beneficial management of the affected patients. Most common neurological manifestations seen include dizziness, headache, impaired consciousness, acute cerebrovascular disease, ataxia, and seizures. Anosmia and ageusia have recently been hinted as significant early symptoms in COVID-19. As cases with neurological deficits in COVID-19 emerge, the overall prognosis is yet unknown.

Authors+Show Affiliations

Department of Medicine and Biological and 2Biomedical Science, Aga Khan University, Karachi.Department of Medicine and Biological and 2Biomedical Science, Aga Khan University, Karachi.Departments of Medicine, Aga Khan University, Karachi.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32515379

Citation

Kanwar, Dureshahwar, et al. "Neurological Manifestations of COVID-19." JPMA. the Journal of the Pakistan Medical Association, vol. 70(Suppl 3), no. 5, 2020, pp. S101-S103.
Kanwar D, Baig AM, Wasay M. Neurological manifestations of COVID-19. J Pak Med Assoc. 2020;70(Suppl 3)(5):S101-S103.
Kanwar, D., Baig, A. M., & Wasay, M. (2020). Neurological manifestations of COVID-19. JPMA. the Journal of the Pakistan Medical Association, 70(Suppl 3)(5), S101-S103. https://doi.org/10.5455/JPMA.20
Kanwar D, Baig AM, Wasay M. Neurological Manifestations of COVID-19. J Pak Med Assoc. 2020;70(Suppl 3)(5):S101-S103. PubMed PMID: 32515379.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurological manifestations of COVID-19. AU - Kanwar,Dureshahwar, AU - Baig,Abdul Mannan, AU - Wasay,Mohammad, PY - 2020/6/10/entrez PY - 2020/6/10/pubmed PY - 2020/6/19/medline KW - Coronavirus, SARS-CoV-2, COVID-19, ACE 2, Neurotoxicity, Brain, Seizures. SP - S101 EP - S103 JF - JPMA. The Journal of the Pakistan Medical Association JO - J Pak Med Assoc VL - 70(Suppl 3) IS - 5 N2 - Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has turned out to be a formidable pandemic. Upcoming evidence from confirmed cases of COVID-19 suggests an anticipated incursion of patients with neurological manifestations in the weeks to come. An expression of the angiotensin-converting enzyme 2 (ACE 2), the cellular receptor for SARS-CoV-2 over the glial cells and neurons have made the brain a potential target. Neurotoxicity may occur as a result of direct, indirect and post-infectious complications. Attention to neurological deficits in COVID-19 is fundamental to ensure appropriate, timely, beneficial management of the affected patients. Most common neurological manifestations seen include dizziness, headache, impaired consciousness, acute cerebrovascular disease, ataxia, and seizures. Anosmia and ageusia have recently been hinted as significant early symptoms in COVID-19. As cases with neurological deficits in COVID-19 emerge, the overall prognosis is yet unknown. SN - 0030-9982 UR - https://www.unboundmedicine.com/medline/citation/32515379/Neurological_manifestations_of_COVID_19_ L2 - https://medlineplus.gov/covid19coronavirusdisease2019.html DB - PRIME DP - Unbound Medicine ER -