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Airborne SARS-CoV-2 Is Rapidly Inactivated by Simulated Sunlight.
J Infect Dis. 2020 07 23; 222(4):564-571.JI

Abstract

Aerosols represent a potential transmission route of COVID-19. This study examined effect of simulated sunlight, relative humidity, and suspension matrix on stability of SARS-CoV-2 in aerosols. Simulated sunlight and matrix significantly affected decay rate of the virus. Relative humidity alone did not affect the decay rate; however, minor interactions between relative humidity and other factors were observed. Mean decay rates (± SD) in simulated saliva, under simulated sunlight levels representative of late winter/early fall and summer were 0.121 ± 0.017 min-1 (90% loss, 19 minutes) and 0.306 ± 0.097 min-1 (90% loss, 8 minutes), respectively. Mean decay rate without simulated sunlight across all relative humidity levels was 0.008 ± 0.011 min-1 (90% loss, 286 minutes). These results suggest that the potential for aerosol transmission of SARS-CoV-2 may be dependent on environmental conditions, particularly sunlight. These data may be useful to inform mitigation strategies to minimize the potential for aerosol transmission.

Authors+Show Affiliations

National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.National Biodefense Analysis and Countermeasures Center, Operated by Battelle National Biodefense Institute for the US Department of Homeland Security Science and Technology Directorate, Frederick, Maryland, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32525979

Citation

Schuit, Michael, et al. "Airborne SARS-CoV-2 Is Rapidly Inactivated By Simulated Sunlight." The Journal of Infectious Diseases, vol. 222, no. 4, 2020, pp. 564-571.
Schuit M, Ratnesar-Shumate S, Yolitz J, et al. Airborne SARS-CoV-2 Is Rapidly Inactivated by Simulated Sunlight. J Infect Dis. 2020;222(4):564-571.
Schuit, M., Ratnesar-Shumate, S., Yolitz, J., Williams, G., Weaver, W., Green, B., Miller, D., Krause, M., Beck, K., Wood, S., Holland, B., Bohannon, J., Freeburger, D., Hooper, I., Biryukov, J., Altamura, L. A., Wahl, V., Hevey, M., & Dabisch, P. (2020). Airborne SARS-CoV-2 Is Rapidly Inactivated by Simulated Sunlight. The Journal of Infectious Diseases, 222(4), 564-571. https://doi.org/10.1093/infdis/jiaa334
Schuit M, et al. Airborne SARS-CoV-2 Is Rapidly Inactivated By Simulated Sunlight. J Infect Dis. 2020 07 23;222(4):564-571. PubMed PMID: 32525979.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Airborne SARS-CoV-2 Is Rapidly Inactivated by Simulated Sunlight. AU - Schuit,Michael, AU - Ratnesar-Shumate,Shanna, AU - Yolitz,Jason, AU - Williams,Gregory, AU - Weaver,Wade, AU - Green,Brian, AU - Miller,David, AU - Krause,Melissa, AU - Beck,Katie, AU - Wood,Stewart, AU - Holland,Brian, AU - Bohannon,Jordan, AU - Freeburger,Denise, AU - Hooper,Idris, AU - Biryukov,Jennifer, AU - Altamura,Louis A, AU - Wahl,Victoria, AU - Hevey,Michael, AU - Dabisch,Paul, PY - 2020/05/04/received PY - 2020/06/08/accepted PY - 2020/6/12/pubmed PY - 2020/8/4/medline PY - 2020/6/12/entrez KW - COVID-19 KW - SARS-CoV-2 KW - aerosol decay KW - aerosol persistence KW - relative humidity KW - sunlight SP - 564 EP - 571 JF - The Journal of infectious diseases JO - J Infect Dis VL - 222 IS - 4 N2 - Aerosols represent a potential transmission route of COVID-19. This study examined effect of simulated sunlight, relative humidity, and suspension matrix on stability of SARS-CoV-2 in aerosols. Simulated sunlight and matrix significantly affected decay rate of the virus. Relative humidity alone did not affect the decay rate; however, minor interactions between relative humidity and other factors were observed. Mean decay rates (± SD) in simulated saliva, under simulated sunlight levels representative of late winter/early fall and summer were 0.121 ± 0.017 min-1 (90% loss, 19 minutes) and 0.306 ± 0.097 min-1 (90% loss, 8 minutes), respectively. Mean decay rate without simulated sunlight across all relative humidity levels was 0.008 ± 0.011 min-1 (90% loss, 286 minutes). These results suggest that the potential for aerosol transmission of SARS-CoV-2 may be dependent on environmental conditions, particularly sunlight. These data may be useful to inform mitigation strategies to minimize the potential for aerosol transmission. SN - 1537-6613 UR - https://www.unboundmedicine.com/medline/citation/32525979/Airborne_SARS_CoV_2_Is_Rapidly_Inactivated_by_Simulated_Sunlight_ L2 - https://academic.oup.com/jid/article-lookup/doi/10.1093/infdis/jiaa334 DB - PRIME DP - Unbound Medicine ER -