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COVID 19 diagnostic multiplicity and its role in community surveillance and control.
Infez Med. 2020 Jun 01; 28(suppl 1):18-28.IM

Abstract

Diagnosis of persons exposed to/infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is central to controlling the global pandemic of COVID-19. Currently, several diagnostic modalities are available for COVID-19, each with its own pros and cons. Although there is a global consensus to increase the testing capacity, it is also essential to prudently utilize these tests to control the pandemic. In this paper, we have reviewed the current array of diagnostics for SARS-CoV-2, highlighted the gaps in current diagnostic modalities, and their role in community surveillance and control of the pandemic. The different modalities of COVID-19 diagnosis discussed are: clinical and radiological, molecular based (laboratory based and point-of-care), Immunoassay based (ELISA, rapid antigen and antibody detection tests) and digital diagnostics (artificial intelligence based algorithms). The role of rapid antigen/antibody detection tests in community surveillance has also been described here. These tests can be used to identify asymptomatic persons exposed to the virus and in community based seroprevalence surveys to assess the epidemiology of spread of the virus. However, there are few concerns about the accuracy of these tests which needs to evaluated beforehand.

Authors+Show Affiliations

Department of Biochemistry, All India Institute of Medical Sciences, Nagpur, India.Department of Anatomy, All India Institute of Medical Sciences, Nagpur, India.Department of Physiology, All India Institute of Medical Sciences, Nagpur, India.Department of Community Medicine, All India Institute of Medical Sciences, Nagpur, India.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32532934

Citation

Tripathi, Satyendra C., et al. "COVID 19 Diagnostic Multiplicity and Its Role in Community Surveillance and Control." Le Infezioni in Medicina, vol. 28, no. suppl 1, 2020, pp. 18-28.
Tripathi SC, Deshmukh V, Patil A, et al. COVID 19 diagnostic multiplicity and its role in community surveillance and control. Infez Med. 2020;28(suppl 1):18-28.
Tripathi, S. C., Deshmukh, V., Patil, A., & Tripathy, J. P. (2020). COVID 19 diagnostic multiplicity and its role in community surveillance and control. Le Infezioni in Medicina, 28(suppl 1), 18-28.
Tripathi SC, et al. COVID 19 Diagnostic Multiplicity and Its Role in Community Surveillance and Control. Infez Med. 2020 Jun 1;28(suppl 1):18-28. PubMed PMID: 32532934.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - COVID 19 diagnostic multiplicity and its role in community surveillance and control. AU - Tripathi,Satyendra C, AU - Deshmukh,Vishwajit, AU - Patil,Ashlesh, AU - Tripathy,Jaya Prasad, PY - 2020/6/14/entrez PY - 2020/6/14/pubmed PY - 2020/6/23/medline SP - 18 EP - 28 JF - Le infezioni in medicina JO - Infez Med VL - 28 IS - suppl 1 N2 - Diagnosis of persons exposed to/infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is central to controlling the global pandemic of COVID-19. Currently, several diagnostic modalities are available for COVID-19, each with its own pros and cons. Although there is a global consensus to increase the testing capacity, it is also essential to prudently utilize these tests to control the pandemic. In this paper, we have reviewed the current array of diagnostics for SARS-CoV-2, highlighted the gaps in current diagnostic modalities, and their role in community surveillance and control of the pandemic. The different modalities of COVID-19 diagnosis discussed are: clinical and radiological, molecular based (laboratory based and point-of-care), Immunoassay based (ELISA, rapid antigen and antibody detection tests) and digital diagnostics (artificial intelligence based algorithms). The role of rapid antigen/antibody detection tests in community surveillance has also been described here. These tests can be used to identify asymptomatic persons exposed to the virus and in community based seroprevalence surveys to assess the epidemiology of spread of the virus. However, there are few concerns about the accuracy of these tests which needs to evaluated beforehand. SN - 1124-9390 UR - https://www.unboundmedicine.com/medline/citation/32532934/COVID_19_diagnostic_multiplicity_and_its_role_in_community_surveillance_and_control_ DB - PRIME DP - Unbound Medicine ER -