Citation
Qiu, Chenghao, et al. "Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: an International Multicenter Study." Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, vol. 163, no. 4, 2020, pp. 714-721.
Qiu C, Cui C, Hautefort C, et al. Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study. Otolaryngol Head Neck Surg. 2020;163(4):714-721.
Qiu, C., Cui, C., Hautefort, C., Haehner, A., Zhao, J., Yao, Q., Zeng, H., Nisenbaum, E. J., Liu, L., Zhao, Y., Zhang, D., Levine, C. G., Cejas, I., Dai, Q., Zeng, M., Herman, P., Jourdaine, C., de With, K., Draf, J., ... Lu, H. (2020). Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study. Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 163(4), 714-721. https://doi.org/10.1177/0194599820934376
Qiu C, et al. Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: an International Multicenter Study. Otolaryngol Head Neck Surg. 2020;163(4):714-721. PubMed PMID: 32539586.
TY - JOUR
T1 - Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study.
AU - Qiu,Chenghao,
AU - Cui,Chong,
AU - Hautefort,Charlotte,
AU - Haehner,Antje,
AU - Zhao,Jun,
AU - Yao,Qi,
AU - Zeng,Hui,
AU - Nisenbaum,Eric J,
AU - Liu,Li,
AU - Zhao,Yu,
AU - Zhang,Di,
AU - Levine,Corinna G,
AU - Cejas,Ivette,
AU - Dai,Qi,
AU - Zeng,Mei,
AU - Herman,Philippe,
AU - Jourdaine,Clement,
AU - de With,Katja,
AU - Draf,Julia,
AU - Chen,Bing,
AU - Jayaweera,Dushyantha T,
AU - Denneny,James C,3rd
AU - Casiano,Roy,
AU - Yu,Hongmeng,
AU - Eshraghi,Adrien A,
AU - Hummel,Thomas,
AU - Liu,Xuezhong,
AU - Shu,Yilai,
AU - Lu,Hongzhou,
Y1 - 2020/06/16/
PY - 2020/6/17/pubmed
PY - 2020/10/21/medline
PY - 2020/6/17/entrez
KW - COVID-19
KW - COVID-19 screening
KW - SARS-CoV-2
KW - anosmia
KW - dysgeusia
KW - gustatory dysfunction
KW - olfactory dysfunction
SP - 714
EP - 721
JF - Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
JO - Otolaryngol Head Neck Surg
VL - 163
IS - 4
N2 - OBJECTIVE: To evaluate the prevalence and characteristics of olfactory or gustatory dysfunction in coronavirus disease 2019 (COVID-19) patients. STUDY DESIGN: Multicenter case series. SETTING: Five tertiary care hospitals (3 in China, 1 in France, 1 in Germany). SUBJECTS AND METHODS: In total, 394 polymerase chain reaction (PCR)-confirmed COVID-19-positive patients were screened, and those with olfactory or gustatory dysfunction were included. Data including demographics, COVID-19 severity, patient outcome, and the incidence and degree of olfactory and/or gustatory dysfunction were collected and analyzed. The Questionnaire of Olfactory Disorders (QOD) and visual analog scale (VAS) were used to quantify olfactory and gustatory dysfunction, respectively. All subjects at 1 hospital (Shanghai) without subjective olfactory complaints underwent objective testing. RESULTS: Of 394 screened subjects, 161 (41%) reported olfactory and/or gustatory dysfunction and were included. Incidence of olfactory and/or gustatory disorders in Chinese (n = 239), German (n = 39), and French (n = 116) cohorts was 32%, 69%, and 49%, respectively. The median age of included subjects was 39 years, 92 of 161 (57%) were male, and 10 of 161 (6%) were children. Of included subjects, 10% had only olfactory or gustatory symptoms, and 19% had olfactory and/or gustatory complaints prior to any other COVID-19 symptom. Of subjects with objective olfactory testing, 10 of 90 demonstrated abnormal chemosensory function despite reporting normal subjective olfaction. Forty-three percent (44/102) of subjects with follow-up showed symptomatic improvement in olfaction or gustation. CONCLUSIONS: Olfactory and/or gustatory disorders may represent early or isolated symptoms of severe acute respiratory syndrome coronavirus 2 infection. They may serve as a useful additional screening criterion, particularly for the identification of patients in the early stages of infection.
SN - 1097-6817
UR - https://www.unboundmedicine.com/medline/citation/32539586/Olfactory_and_Gustatory_Dysfunction_as_an_Early_Identifier_of_COVID_19_in_Adults_and_Children:_An_International_Multicenter_Study_
DB - PRIME
DP - Unbound Medicine
ER -