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Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection.
J Pediatr. 2020 09; 224:141-145.JPed

Abstract

We report on the presentation and course of 33 children with multisystem inflammatory syndrome in children and confirmed severe acute respiratory syndrome coronavirus 2 infection. Hemodynamic instability and cardiac dysfunction were prominent findings, with most patients exhibiting rapid resolution following anti-inflammatory therapy.

Authors+Show Affiliations

Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY. Electronic address: cschleien@northwell.edu.No affiliation info availableDepartment of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Institute of Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY.Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY; Institute of Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32553873

Citation

Capone, Christine A., et al. "Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection." The Journal of Pediatrics, vol. 224, 2020, pp. 141-145.
Capone CA, Subramony A, Sweberg T, et al. Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection. J Pediatr. 2020;224:141-145.
Capone, C. A., Subramony, A., Sweberg, T., Schneider, J., Shah, S., Rubin, L., Schleien, C., Epstein, S., Johnson, J. C., Kessel, A., Misra, N., Mitchell, E., Palumbo, N., Rajan, S., Rocker, J., Williamson, K., & Davidson, K. W. (2020). Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection. The Journal of Pediatrics, 224, 141-145. https://doi.org/10.1016/j.jpeds.2020.06.044
Capone CA, et al. Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection. J Pediatr. 2020;224:141-145. PubMed PMID: 32553873.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection. AU - Capone,Christine A, AU - Subramony,Anupama, AU - Sweberg,Todd, AU - Schneider,James, AU - Shah,Sareen, AU - Rubin,Lorry, AU - Schleien,Charles, AU - ,, AU - Epstein,Shilpi, AU - Johnson,Jennifer C, AU - Kessel,Aaron, AU - Misra,Nila, AU - Mitchell,Elizabeth, AU - Palumbo,Nancy, AU - Rajan,Sujatha, AU - Rocker,Josh, AU - Williamson,Kristy, AU - Davidson,Karina W, Y1 - 2020/06/14/ PY - 2020/06/02/received PY - 2020/06/09/revised PY - 2020/06/10/accepted PY - 2020/6/20/pubmed PY - 2020/9/12/medline PY - 2020/6/20/entrez KW - adolescents KW - coronary aneurysm KW - inflammation KW - kawasaki disease SP - 141 EP - 145 JF - The Journal of pediatrics JO - J Pediatr VL - 224 N2 - We report on the presentation and course of 33 children with multisystem inflammatory syndrome in children and confirmed severe acute respiratory syndrome coronavirus 2 infection. Hemodynamic instability and cardiac dysfunction were prominent findings, with most patients exhibiting rapid resolution following anti-inflammatory therapy. SN - 1097-6833 UR - https://www.unboundmedicine.com/medline/citation/32553873/Characteristics_Cardiac_Involvement_and_Outcomes_of_Multisystem_Inflammatory_Syndrome_of_Childhood_Associated_with_severe_acute_respiratory_syndrome_coronavirus_2_Infection_ DB - PRIME DP - Unbound Medicine ER -