Tags

Type your tag names separated by a space and hit enter

Coronavirus Disease (COVID-19) and the Gastrointestinal System in Children.
Indian Pediatr. 2020 Jun 15; 57(6):533-535.IP

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), though primarily a respiratory pathogen, also involves the gastrointestinal tract. Similar to the respiratory mucosa, angiotensin converting enzyme-2 (ACE-2) receptor and transmembrane serine protease 2 (TMPRSS2) co-express in the gastrointestinal tract, which facilitates viral entry into the tissue. Less than 10% of children with infection develop diarrhea and vomiting. Prolonged RT PCR positivity in the stool has raised the possibility of feco-oral transmission. Elevated transaminases are common, especially in those with severe coronavirus disease (COVID-19). Children with inflammatory bowel disease and post liver transplant patients do not have an increased risk of disease, and should remain on medications they are already on. Children with chronic liver disease should continue their medications as usual. All elective procedures like endoscopy should be postponed.

Authors+Show Affiliations

Masonic Medical Centre, Coimbatore, Tamil Nadu, India. Correspondence to: Prof John Matthai, Pediatric Gastroenterologist, Masonic Medical center, Race course, Coimbatore 641004, Tamil Nadu, India. psg_peds@yahoo.com.Dr Rela Institute and Medical Center, Chennai, Tamil Nadu, India.Government Medical College, Thiruvananthapuram, Kerala, India.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32562397

Citation

Matthai, John, et al. "Coronavirus Disease (COVID-19) and the Gastrointestinal System in Children." Indian Pediatrics, vol. 57, no. 6, 2020, pp. 533-535.
Matthai J, Shanmugam N, Sobhan P, et al. Coronavirus Disease (COVID-19) and the Gastrointestinal System in Children. Indian Pediatr. 2020;57(6):533-535.
Matthai, J., Shanmugam, N., & Sobhan, P. (2020). Coronavirus Disease (COVID-19) and the Gastrointestinal System in Children. Indian Pediatrics, 57(6), 533-535.
Matthai J, et al. Coronavirus Disease (COVID-19) and the Gastrointestinal System in Children. Indian Pediatr. 2020 Jun 15;57(6):533-535. PubMed PMID: 32562397.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coronavirus Disease (COVID-19) and the Gastrointestinal System in Children. AU - Matthai,John, AU - Shanmugam,Naresh, AU - Sobhan,Prasanth, AU - ,, PY - 2020/6/21/entrez PY - 2020/6/21/pubmed PY - 2020/7/8/medline SP - 533 EP - 535 JF - Indian pediatrics JO - Indian Pediatr VL - 57 IS - 6 N2 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), though primarily a respiratory pathogen, also involves the gastrointestinal tract. Similar to the respiratory mucosa, angiotensin converting enzyme-2 (ACE-2) receptor and transmembrane serine protease 2 (TMPRSS2) co-express in the gastrointestinal tract, which facilitates viral entry into the tissue. Less than 10% of children with infection develop diarrhea and vomiting. Prolonged RT PCR positivity in the stool has raised the possibility of feco-oral transmission. Elevated transaminases are common, especially in those with severe coronavirus disease (COVID-19). Children with inflammatory bowel disease and post liver transplant patients do not have an increased risk of disease, and should remain on medications they are already on. Children with chronic liver disease should continue their medications as usual. All elective procedures like endoscopy should be postponed. SN - 0974-7559 UR - https://www.unboundmedicine.com/medline/citation/32562397/Coronavirus_Disease__COVID_19__and_the_Gastrointestinal_System_in_Children_ L2 - https://www.indianpediatrics.net/june2020/533.pdf DB - PRIME DP - Unbound Medicine ER -