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COVID-19 and anosmia: A review based on up-to-date knowledge.
Am J Otolaryngol. 2020 Sep - Oct; 41(5):102581.AJ

Abstract

The pandemic of Coronavirus Disease 2019 (COVID-19) has caused a vast disaster throughout the world. There is increasing evidence that olfactory dysfunction can present in COVID-19 patients. Anosmia can occur alone or can be accompanied by other symptoms of COVID-19, such as a dry cough. However, the pathogenic mechanism of olfactory dysfunction and its clinical characteristics in patients with COVID-19 remains unclear. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction in COVID-19 patients varies from 33.9-68% with female dominance. Anosmia and dysgeusia are often comorbid in COVID-19 patients. Otolaryngologists should be mindful of the symptom of anosmia in outpatients so as not to delay the diagnosis of COVID-19. In this paper, we have reviewed the relevant knowledge based on up-to-date literature.

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Authors+Show Affiliations

Meng X
Department of Otolaryngology, Wuxi Huishan District People's Hospital, 2 Zhanqian North Road, Luoshe Town, Huishan District, Wuxi 214187, PR China. Electronic address: xiangming_meng@hotmail.com.
Deng Y
Department of Anesthesiology, Wuxi Huishan District People's Hospital, 2 Zhanqian North Road, Luoshe Town, Huishan District, Wuxi 214187, PR China.
Dai Z
Department of Otolaryngology, Wuxi Huishan District People's Hospital, 2 Zhanqian North Road, Luoshe Town, Huishan District, Wuxi 214187, PR China.
Meng Z
Faculty of Information Engineering and Automation, Kunming University of Science and Technology, No.727 South Jingming Road, Chenggong District, Kunming 650500, PR China.

MeSH

BetacoronavirusCOVID-19Coronavirus InfectionsHumansOlfaction DisordersPandemicsPneumonia, ViralSARS-CoV-2

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32563019

Clinical Trial Links

Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 Parosmia
LOng COvid COmorbidities: Andrological, Reproductive, Sexual Dysfunctions in Patients Recovered From COVID-19

Citation

Meng, Xiangming, et al. "COVID-19 and Anosmia: a Review Based On Up-to-date Knowledge." American Journal of Otolaryngology, vol. 41, no. 5, 2020, p. 102581.
Meng X, Deng Y, Dai Z, et al. COVID-19 and anosmia: A review based on up-to-date knowledge. Am J Otolaryngol. 2020;41(5):102581.
Meng, X., Deng, Y., Dai, Z., & Meng, Z. (2020). COVID-19 and anosmia: A review based on up-to-date knowledge. American Journal of Otolaryngology, 41(5), 102581. https://doi.org/10.1016/j.amjoto.2020.102581
Meng X, et al. COVID-19 and Anosmia: a Review Based On Up-to-date Knowledge. Am J Otolaryngol. 2020 Sep - Oct;41(5):102581. PubMed PMID: 32563019.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - COVID-19 and anosmia: A review based on up-to-date knowledge. AU - Meng,Xiangming, AU - Deng,Yanzhong, AU - Dai,Zhiyong, AU - Meng,Zhisheng, Y1 - 2020/06/02/ PY - 2020/05/05/received PY - 2020/05/24/accepted PY - 2020/6/21/pubmed PY - 2020/9/4/medline PY - 2020/6/21/entrez KW - Anosmia KW - COVID-19 KW - Coronavirus KW - Olfactory dysfunction KW - Otolaryngology KW - SARS-CoV-2 KW - Smell SP - 102581 EP - 102581 JF - American journal of otolaryngology JO - Am J Otolaryngol VL - 41 IS - 5 N2 - The pandemic of Coronavirus Disease 2019 (COVID-19) has caused a vast disaster throughout the world. There is increasing evidence that olfactory dysfunction can present in COVID-19 patients. Anosmia can occur alone or can be accompanied by other symptoms of COVID-19, such as a dry cough. However, the pathogenic mechanism of olfactory dysfunction and its clinical characteristics in patients with COVID-19 remains unclear. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction in COVID-19 patients varies from 33.9-68% with female dominance. Anosmia and dysgeusia are often comorbid in COVID-19 patients. Otolaryngologists should be mindful of the symptom of anosmia in outpatients so as not to delay the diagnosis of COVID-19. In this paper, we have reviewed the relevant knowledge based on up-to-date literature. SN - 1532-818X UR - https://www.unboundmedicine.com/medline/citation/32563019/COVID_19_and_anosmia:_A_review_based_on_up_to_date_knowledge_ DB - PRIME DP - Unbound Medicine ER -