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COVID-19 - Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused by Genetic and Gender Differences in the Response to Viral ACE 2 Attack?
Heart Lung Circ. 2020 Jul; 29(7):964-972.HL

Abstract

Debate continues in the medical literature on the role of the renin angiotensin system (RAS) in Coronavirus disease 2019 (COVID-19) pathophysiology and the implications for the use of cardiovascular drugs acting on the RAS. Could these drugs - which include angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptors blockers (ARBs) - be harmful or potential key therapeutic agents in COVID-19? And, could potentially helpful measures be available and in plain view on the pharmacy shelf?

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Authors+Show Affiliations

Arnold RH
Orange Health Service, Orange, NSW, Australia. Electronic address: ruth@coldhearts.com.au.

MeSH

Angiotensin-Converting Enzyme 2BetacoronavirusCOVID-19Coronavirus InfectionsHumansMortalityPandemicsPeptidyl-Dipeptidase APneumonia, ViralRenin-Angiotensin SystemRisk FactorsSARS-CoV-2Virus Internalization

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32564908

Citation

Arnold, Ruth H.. "COVID-19 - Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused By Genetic and Gender Differences in the Response to Viral ACE 2 Attack?" Heart, Lung & Circulation, vol. 29, no. 7, 2020, pp. 964-972.
Arnold RH. COVID-19 - Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused by Genetic and Gender Differences in the Response to Viral ACE 2 Attack? Heart Lung Circ. 2020;29(7):964-972.
Arnold, R. H. (2020). COVID-19 - Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused by Genetic and Gender Differences in the Response to Viral ACE 2 Attack? Heart, Lung & Circulation, 29(7), 964-972. https://doi.org/10.1016/j.hlc.2020.05.004
Arnold RH. COVID-19 - Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused By Genetic and Gender Differences in the Response to Viral ACE 2 Attack. Heart Lung Circ. 2020;29(7):964-972. PubMed PMID: 32564908.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - COVID-19 - Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused by Genetic and Gender Differences in the Response to Viral ACE 2 Attack? A1 - Arnold,Ruth H, Y1 - 2020/05/25/ PY - 2020/03/28/received PY - 2020/05/05/revised PY - 2020/05/07/accepted PY - 2020/6/23/pubmed PY - 2020/8/19/medline PY - 2020/6/23/entrez KW - Angiotensin converting enzyme inhibitors KW - Angiotensin receptor blockers KW - COVID 19 KW - Neprilysin KW - Renin angiotensin system KW - Vitamin D SP - 964 EP - 972 JF - Heart, lung & circulation JO - Heart Lung Circ VL - 29 IS - 7 N2 - Debate continues in the medical literature on the role of the renin angiotensin system (RAS) in Coronavirus disease 2019 (COVID-19) pathophysiology and the implications for the use of cardiovascular drugs acting on the RAS. Could these drugs - which include angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptors blockers (ARBs) - be harmful or potential key therapeutic agents in COVID-19? And, could potentially helpful measures be available and in plain view on the pharmacy shelf? SN - 1444-2892 UR - https://www.unboundmedicine.com/medline/citation/32564908/COVID_19___Does_This_Disease_Kill_Due_to_Imbalance_of_the_Renin_Angiotensin_System__RAS__Caused_by_Genetic_and_Gender_Differences_in_the_Response_to_Viral_ACE_2_Attack DB - PRIME DP - Unbound Medicine ER -