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A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance.
J Korean Med Sci. 2020 Jun 22; 35(24):e231.JK

Abstract

There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.

Authors+Show Affiliations

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea.Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea.Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. njkmd@snu.ac.kr.Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

32567262

Citation

Ahn, Byeong Yun, et al. "A Case of Breakthrough COVID-19 During Hydroxychloroquine Maintenance." Journal of Korean Medical Science, vol. 35, no. 24, 2020, pp. e231.
Ahn BY, Kang CK, Seo JD, et al. A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance. J Korean Med Sci. 2020;35(24):e231.
Ahn, B. Y., Kang, C. K., Seo, J. D., Choe, P. G., Song, S. H., Park, W. B., Park, S. W., Kim, N. J., & Oh, M. D. (2020). A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance. Journal of Korean Medical Science, 35(24), e231. https://doi.org/10.3346/jkms.2020.35.e231
Ahn BY, et al. A Case of Breakthrough COVID-19 During Hydroxychloroquine Maintenance. J Korean Med Sci. 2020 Jun 22;35(24):e231. PubMed PMID: 32567262.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance. AU - Ahn,Byeong Yun, AU - Kang,Chang Kyung, AU - Seo,Jong Do, AU - Choe,Pyoeng Gyun, AU - Song,Sang Hoon, AU - Park,Wan Beom, AU - Park,Sang Won, AU - Kim,Nam Joong, AU - Oh,Myoung Don, Y1 - 2020/06/22/ PY - 2020/05/30/received PY - 2020/06/07/accepted PY - 2020/6/23/entrez PY - 2020/6/23/pubmed PY - 2020/7/1/medline KW - COVID-19 KW - Hydroxychloroquine KW - Prophylaxis KW - SARS-CoV-2 SP - e231 EP - e231 JF - Journal of Korean medical science JO - J Korean Med Sci VL - 35 IS - 24 N2 - There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19. SN - 1598-6357 UR - https://www.unboundmedicine.com/medline/citation/32567262/A_Case_of_Breakthrough_COVID_19_during_Hydroxychloroquine_Maintenance_ L2 - https://jkms.org/DOIx.php?id=10.3346/jkms.2020.35.e231 DB - PRIME DP - Unbound Medicine ER -