Tags

Type your tag names separated by a space and hit enter

Complications in skin grafts when continuing antithrombotic therapy prior to cutaneous surgery requiring skin grafting: an observational study.
J Plast Surg Hand Surg. 2020 Jun 21 [Online ahead of print]JP

Abstract

Use of anticoagulants is common and practice regarding continuation or discontinuation of the medication peri-operatively for cutaneous surgery lacks evidence-based consensus. Therefore, we aimed to do a prospective observational study with patients who were referred to cutaneous surgery and needed full thickness or split skin grafting and using antitrombotic or non-antitrombotic therapies. Data on patients characteristics, diagnosis, location of surgery and surgery performed, antithrombotic medication and complications in skin grafts were collected. Skin grafts were traced on a transparent film and areas of unhealed skin graft were marked. All patients were routinely followed-up on days 5-7 postoperative. Chi-square test, Fisher's exact test or Mann-Whitney U-test were used to compare patients taking antitrombotic medication with patients receiving no antitrombotic therapy. In addition, associations were calculated for treatment with the different antithrombotic therapies. No severe bleeding requiring blood transfusion or re-operation was observed in this study. The results showed no statistically significant difference between patients who continued treatment with antithrombotic therapy compared with patients having no antithrombotic treatment regarding sub graft hematomas or graft take. Continuing antithrombotic monotheraphy with acetylsalicylic, clopidogrel, warfarin or fish oil in relations to cutaneous surgery do not seem to increase risk of haematoma or graft lost.

Authors+Show Affiliations

Clinic for Surgery and Cancer Treatment and Clinical Nursing Research Unit, Aalborg University Hospital, Aalborg, Denmark.Department of Plastic and Reconstructive Surgery, Aalborg University Hospital, Aalborg, Denmark.Department of Plastic and Breast Surgery, Zealand University Hospital, Aalborg, Denmark.Department of Plastic and Reconstructive Surgery, Aalborg University Hospital, Aalborg, Denmark.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32567446

Citation

Jørgensen, Lone, et al. "Complications in Skin Grafts when Continuing Antithrombotic Therapy Prior to Cutaneous Surgery Requiring Skin Grafting: an Observational Study." Journal of Plastic Surgery and Hand Surgery, 2020, pp. 1-6.
Jørgensen L, Matzen RD, Albertsdottir E, et al. Complications in skin grafts when continuing antithrombotic therapy prior to cutaneous surgery requiring skin grafting: an observational study. J Plast Surg Hand Surg. 2020.
Jørgensen, L., Matzen, R. D., Albertsdottir, E., & Birk-Sørensen, L. (2020). Complications in skin grafts when continuing antithrombotic therapy prior to cutaneous surgery requiring skin grafting: an observational study. Journal of Plastic Surgery and Hand Surgery, 1-6. https://doi.org/10.1080/2000656X.2020.1781141
Jørgensen L, et al. Complications in Skin Grafts when Continuing Antithrombotic Therapy Prior to Cutaneous Surgery Requiring Skin Grafting: an Observational Study. J Plast Surg Hand Surg. 2020 Jun 21;1-6. PubMed PMID: 32567446.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Complications in skin grafts when continuing antithrombotic therapy prior to cutaneous surgery requiring skin grafting: an observational study. AU - Jørgensen,Lone, AU - Matzen,Reem Dina, AU - Albertsdottir,Elin, AU - Birk-Sørensen,Lene, Y1 - 2020/06/21/ PY - 2020/6/23/entrez KW - Skin grafts KW - antithrombotic therapy KW - cutaneous surgery SP - 1 EP - 6 JF - Journal of plastic surgery and hand surgery JO - J Plast Surg Hand Surg N2 - Use of anticoagulants is common and practice regarding continuation or discontinuation of the medication peri-operatively for cutaneous surgery lacks evidence-based consensus. Therefore, we aimed to do a prospective observational study with patients who were referred to cutaneous surgery and needed full thickness or split skin grafting and using antitrombotic or non-antitrombotic therapies. Data on patients characteristics, diagnosis, location of surgery and surgery performed, antithrombotic medication and complications in skin grafts were collected. Skin grafts were traced on a transparent film and areas of unhealed skin graft were marked. All patients were routinely followed-up on days 5-7 postoperative. Chi-square test, Fisher's exact test or Mann-Whitney U-test were used to compare patients taking antitrombotic medication with patients receiving no antitrombotic therapy. In addition, associations were calculated for treatment with the different antithrombotic therapies. No severe bleeding requiring blood transfusion or re-operation was observed in this study. The results showed no statistically significant difference between patients who continued treatment with antithrombotic therapy compared with patients having no antithrombotic treatment regarding sub graft hematomas or graft take. Continuing antithrombotic monotheraphy with acetylsalicylic, clopidogrel, warfarin or fish oil in relations to cutaneous surgery do not seem to increase risk of haematoma or graft lost. SN - 2000-6764 UR - https://www.unboundmedicine.com/medline/citation/32567446/Complications_in_skin_grafts_when_continuing_antithrombotic_therapy_prior_to_cutaneous_surgery_requiring_skin_grafting:_an_observational_study L2 - http://www.tandfonline.com/doi/full/10.1080/2000656X.2020.1781141 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.