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CLEARANCE OF MYCOPLASMA GENITALIUM AND TRICHOMONAS VAGINALIS AMONG ADOLESCENTS AND YOUNG ADULTS WITH PELVIC INFLAMMATORY DISEASE: RESULTS FROM THE TECH-N STUDY.
Sex Transm Dis. 2020 Jun 18 [Online ahead of print]ST

Abstract

Current PID treatment effectively treats Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT). However, coverage may be inadequate for Mycoplasma genitalium (MG)/Trichomonas vaginalis (TV) infections. We compared the longitudinal MG and TV outcomes with NG/CT outcomes for women enrolled in a longitudinal randomized controlled trial to optimize outcomes after PID. The prevalence of CT and NG were lower at 30 days and 90 days follow-up compared to the prevalence at time of diagnosis. No significant difference was observed for MG (OR 0.95, 0.86-1.04, p-0.265) and TV (OR 0.89, 0.75-1.04, p-0.146) over time for both treatment groups, showing that persistence and or reinfection with MG and TV occur more frequently than with CT or NG following treatment for PID using current national treatment guidelines.

Authors+Show Affiliations

Department of Pediatrics.Department of Pediatrics.Department of Pediatrics.Department of Pediatrics.Department of Pediatrics.Department of Pediatrics.Department of Pediatrics.Department of Pediatrics.Department of Adult Emergency Medicine.Department of Pediatrics.Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32569258

Citation

Trent, Maria, et al. "CLEARANCE of MYCOPLASMA GENITALIUM and TRICHOMONAS VAGINALIS AMONG ADOLESCENTS and YOUNG ADULTS WITH PELVIC INFLAMMATORY DISEASE: RESULTS FROM the TECH-N STUDY." Sexually Transmitted Diseases, 2020.
Trent M, Yusuf HE, Perin J, et al. CLEARANCE OF MYCOPLASMA GENITALIUM AND TRICHOMONAS VAGINALIS AMONG ADOLESCENTS AND YOUNG ADULTS WITH PELVIC INFLAMMATORY DISEASE: RESULTS FROM THE TECH-N STUDY. Sex Transm Dis. 2020.
Trent, M., Yusuf, H. E., Perin, J., Anders, J., Chung, S. E., Tabacco-Saeed, L., Rowell, J., Huettner, S., Rothman, R., Butz, A., & Gaydos, C. A. (2020). CLEARANCE OF MYCOPLASMA GENITALIUM AND TRICHOMONAS VAGINALIS AMONG ADOLESCENTS AND YOUNG ADULTS WITH PELVIC INFLAMMATORY DISEASE: RESULTS FROM THE TECH-N STUDY. Sexually Transmitted Diseases. https://doi.org/10.1097/OLQ.0000000000001221
Trent M, et al. CLEARANCE of MYCOPLASMA GENITALIUM and TRICHOMONAS VAGINALIS AMONG ADOLESCENTS and YOUNG ADULTS WITH PELVIC INFLAMMATORY DISEASE: RESULTS FROM the TECH-N STUDY. Sex Transm Dis. 2020 Jun 18; PubMed PMID: 32569258.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - CLEARANCE OF MYCOPLASMA GENITALIUM AND TRICHOMONAS VAGINALIS AMONG ADOLESCENTS AND YOUNG ADULTS WITH PELVIC INFLAMMATORY DISEASE: RESULTS FROM THE TECH-N STUDY. AU - Trent,Maria, AU - Yusuf,Hasiya E, AU - Perin,Jamie, AU - Anders,Jennifer, AU - Chung,Shang-En, AU - Tabacco-Saeed,Lisa, AU - Rowell,Julia, AU - Huettner,Steven, AU - Rothman,Richard, AU - Butz,Arlene, AU - Gaydos,Charlotte A, Y1 - 2020/06/18/ PY - 2020/6/23/entrez PY - 2020/6/23/pubmed PY - 2020/6/23/medline JF - Sexually transmitted diseases JO - Sex Transm Dis N2 - Current PID treatment effectively treats Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT). However, coverage may be inadequate for Mycoplasma genitalium (MG)/Trichomonas vaginalis (TV) infections. We compared the longitudinal MG and TV outcomes with NG/CT outcomes for women enrolled in a longitudinal randomized controlled trial to optimize outcomes after PID. The prevalence of CT and NG were lower at 30 days and 90 days follow-up compared to the prevalence at time of diagnosis. No significant difference was observed for MG (OR 0.95, 0.86-1.04, p-0.265) and TV (OR 0.89, 0.75-1.04, p-0.146) over time for both treatment groups, showing that persistence and or reinfection with MG and TV occur more frequently than with CT or NG following treatment for PID using current national treatment guidelines. SN - 1537-4521 UR - https://www.unboundmedicine.com/medline/citation/32569258/CLEARANCE_OF_MYCOPLASMA_GENITALIUM_AND_TRICHOMONAS_VAGINALIS_AMONG_ADOLESCENTS_AND_YOUNG_ADULTS_WITH_PELVIC_INFLAMMATORY_DISEASE:_RESULTS_FROM_THE_TECH-N_STUDY L2 - https://doi.org/10.1097/OLQ.0000000000001221 DB - PRIME DP - Unbound Medicine ER -