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Evaluation of Conjunctival Swab PCR Results in Patients with SARS-CoV-2 Infection.
Ocul Immunol Inflamm. 2020 Jul 03; 28(5):745-748.OI

Abstract

PURPOSE

The study objective was to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in conjunctival swabs from patients with confirmed SARS-CoV-2 infection.

METHODS

Forty patients who tested positive by real-time reverse transcription (rRT)-polymerase chain reaction (PCR) of nasopharyngeal and oropharyngeal swabs were enrolled. Conjunctival swabbing was used to collect the tear and conjunctival secretions of patients.

RESULTS

Conjunctival swab rRT-PCR was positive for three patients and negative for 37 patients. Ten of the patients (25%) were diagnosed with conjunctivitis during the ophthalmic examination. Of these patients, one was found positive by conjunctival swab rRT-PCR, and nine were found negative. The difference between patients who tested positive or negative using conjunctival swab rRT-PCR was without statistical significance in terms of the presence of conjunctivitis (p = .720).

CONCLUSION

The rate of positivity from conjunctival swab rRT-PCR was 7.5% in patients with confirmed SARS-CoV-2 infection.

Authors+Show Affiliations

Department of Ophthalmology, Sakarya University Training and Research Hospital , Sakarya, Turkey.Department of Ophthalmology, Sakarya University Training and Research Hospital , Sakarya, Turkey.Department of Ophthalmology, Sakarya University Training and Research Hospital , Sakarya, Turkey.Department of Infectious Diseases and Clinical Microbiology, Sakarya University Training and Research Hospital , Sakarya, Turkey.Department of Microbiology, Sakarya University Training and Research Hospital , Sakarya, Turkey.Department of Infectious Diseases and Clinical Microbiology, Sakarya University Training and Research Hospital , Sakarya, Turkey.Department of Ophthalmology, Sakarya University Training and Research Hospital , Sakarya, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32569495

Citation

Atum, Mahmut, et al. "Evaluation of Conjunctival Swab PCR Results in Patients With SARS-CoV-2 Infection." Ocular Immunology and Inflammation, vol. 28, no. 5, 2020, pp. 745-748.
Atum M, Boz AAE, Çakır B, et al. Evaluation of Conjunctival Swab PCR Results in Patients with SARS-CoV-2 Infection. Ocul Immunol Inflamm. 2020;28(5):745-748.
Atum, M., Boz, A. A. E., Çakır, B., Karabay, O., Köroğlu, M., Öğütlü, A., & Alagöz, G. (2020). Evaluation of Conjunctival Swab PCR Results in Patients with SARS-CoV-2 Infection. Ocular Immunology and Inflammation, 28(5), 745-748. https://doi.org/10.1080/09273948.2020.1775261
Atum M, et al. Evaluation of Conjunctival Swab PCR Results in Patients With SARS-CoV-2 Infection. Ocul Immunol Inflamm. 2020 Jul 3;28(5):745-748. PubMed PMID: 32569495.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of Conjunctival Swab PCR Results in Patients with SARS-CoV-2 Infection. AU - Atum,Mahmut, AU - Boz,Ali Altan Ertan, AU - Çakır,Burçin, AU - Karabay,Oğuz, AU - Köroğlu,Mehmet, AU - Öğütlü,Aziz, AU - Alagöz,Gürsoy, Y1 - 2020/06/22/ PY - 2020/6/23/pubmed PY - 2020/8/7/medline PY - 2020/6/23/entrez KW - SARS-CoV-2 KW - conjunctival swab KW - ocular disease SP - 745 EP - 748 JF - Ocular immunology and inflammation JO - Ocul. Immunol. Inflamm. VL - 28 IS - 5 N2 - PURPOSE: The study objective was to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in conjunctival swabs from patients with confirmed SARS-CoV-2 infection. METHODS: Forty patients who tested positive by real-time reverse transcription (rRT)-polymerase chain reaction (PCR) of nasopharyngeal and oropharyngeal swabs were enrolled. Conjunctival swabbing was used to collect the tear and conjunctival secretions of patients. RESULTS: Conjunctival swab rRT-PCR was positive for three patients and negative for 37 patients. Ten of the patients (25%) were diagnosed with conjunctivitis during the ophthalmic examination. Of these patients, one was found positive by conjunctival swab rRT-PCR, and nine were found negative. The difference between patients who tested positive or negative using conjunctival swab rRT-PCR was without statistical significance in terms of the presence of conjunctivitis (p = .720). CONCLUSION: The rate of positivity from conjunctival swab rRT-PCR was 7.5% in patients with confirmed SARS-CoV-2 infection. SN - 1744-5078 UR - https://www.unboundmedicine.com/medline/citation/32569495/Evaluation_of_Conjunctival_Swab_PCR_Results_in_Patients_with_SARS_CoV_2_Infection_ L2 - http://www.tandfonline.com/doi/full/10.1080/09273948.2020.1775261 DB - PRIME DP - Unbound Medicine ER -