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A 56-year-old man with RT-PCR negative nasopharyngeal swabs with Coronavirus Disease 2019 (COVID-19) Pneumonia.
Ann Agric Environ Med. 2020 Jun 19; 27(2):317-318.AA

Abstract

INTRODUCTION

Diagnostic procedure in Coronavirus Disease 2019 (COVID-19) is based mainly on performing real-time-reverse transcription-polymerase chain-reaction (RT-PCR), which has been accepted as the gold standard method. In some cases, such as mutations of the SARS-CoV-2 genome, variable viral load kinetics or laboratory errors, it can be false-negative.

CASE REPORT

The case is presented of a 56-year-old man with respiratory tract symptoms, with twice negative results of real-time-reverse transcription-polymerase chain-reaction of nasopharyngeal swabs and positive chest computed tomography, with typical findings for COVID-19 pneumonia.

CONCLUSIONS

Patients with negative RT-PCR results, but with positive computed tomography findings characteristic for COVID-19, should be treated as well as those infected.

Authors+Show Affiliations

Chair and Department of Infectious Diseases, Medical University, Lublin, Poland.Chair and Department of Infectious Diseases, Medical University, Lublin, Poland.Chair and Department of Internal Diseases, Medical University, Lublin, Poland.Institute of Rural Health, Lublin, Poland.Chair and Department of Infectious Diseases, Medical University, Lublin, Poland.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

32588614

Citation

Dworzańska, Anna, et al. "A 56-year-old Man With RT-PCR Negative Nasopharyngeal Swabs With Coronavirus Disease 2019 (COVID-19) Pneumonia." Annals of Agricultural and Environmental Medicine : AAEM, vol. 27, no. 2, 2020, pp. 317-318.
Dworzańska A, Tudrujek-Zdunek M, Mosiewicz J, et al. A 56-year-old man with RT-PCR negative nasopharyngeal swabs with Coronavirus Disease 2019 (COVID-19) Pneumonia. Ann Agric Environ Med. 2020;27(2):317-318.
Dworzańska, A., Tudrujek-Zdunek, M., Mosiewicz, J., Panasiuk, L., & Tomasiewicz, K. (2020). A 56-year-old man with RT-PCR negative nasopharyngeal swabs with Coronavirus Disease 2019 (COVID-19) Pneumonia. Annals of Agricultural and Environmental Medicine : AAEM, 27(2), 317-318. https://doi.org/10.26444/aaem/123543
Dworzańska A, et al. A 56-year-old Man With RT-PCR Negative Nasopharyngeal Swabs With Coronavirus Disease 2019 (COVID-19) Pneumonia. Ann Agric Environ Med. 2020 Jun 19;27(2):317-318. PubMed PMID: 32588614.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A 56-year-old man with RT-PCR negative nasopharyngeal swabs with Coronavirus Disease 2019 (COVID-19) Pneumonia. AU - Dworzańska,Anna, AU - Tudrujek-Zdunek,Magdalena, AU - Mosiewicz,Jerzy, AU - Panasiuk,Lech, AU - Tomasiewicz,Krzysztof, Y1 - 2020/06/19/ PY - 2020/6/27/entrez PY - 2020/6/27/pubmed PY - 2020/7/4/medline KW - COVID-19 KW - Coronavirus Disease 2019 KW - RT-PCR KW - chest computed tomography KW - pneumonia KW - real-time-reverse transcription-polymerase chain-reaction SP - 317 EP - 318 JF - Annals of agricultural and environmental medicine : AAEM JO - Ann Agric Environ Med VL - 27 IS - 2 N2 - INTRODUCTION: Diagnostic procedure in Coronavirus Disease 2019 (COVID-19) is based mainly on performing real-time-reverse transcription-polymerase chain-reaction (RT-PCR), which has been accepted as the gold standard method. In some cases, such as mutations of the SARS-CoV-2 genome, variable viral load kinetics or laboratory errors, it can be false-negative. CASE REPORT: The case is presented of a 56-year-old man with respiratory tract symptoms, with twice negative results of real-time-reverse transcription-polymerase chain-reaction of nasopharyngeal swabs and positive chest computed tomography, with typical findings for COVID-19 pneumonia. CONCLUSIONS: Patients with negative RT-PCR results, but with positive computed tomography findings characteristic for COVID-19, should be treated as well as those infected. SN - 1898-2263 UR - https://www.unboundmedicine.com/medline/citation/32588614/A_56_year_old_man_with_RT_PCR_negative_nasopharyngeal_swabs_with_Coronavirus_Disease_2019__COVID_19__Pneumonia_ L2 - https://doi.org/10.26444/aaem/123543 DB - PRIME DP - Unbound Medicine ER -