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Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection.
Virus Res. 2020 09; 286:198073.VR

Abstract

The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global pandemic. Up to now, numerous medicines have been applied or approved for the prevention and control of the virus infection. However, the efficiency of each medicine or combination is completely different or still unknown. In this review, we discuss the types, characteristics, antiviral mechanisms, and shortcomings of recommended candidate medicines for SARS-CoV-2 infection, as well as perspectives of the drugs for the disease treatment, which may provide a theoretical basis for drug screening and application.

Links

Publisher Full Text
ncbi.nlm.nih.gov
linkinghub.elsevier.com
PMC Free PDF

Authors+Show Affiliations

Li C
Research Unit of Key Technologies for Prevention and Control of Virus Zoonoses, Chinese Academy of Medical Sciences, Military Veterinary Institute, Academy of Military Medical Sciences, Changchun, 130122, China.
Wang L
Key Lab for Zoonoses Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun 130062, China.
Ren L
Key Lab for Zoonoses Research, Ministry of Education, Jilin Provincial Key Laboratory of Animal Embryo Engineering, College of Animal Sciences, Jilin University, Changchun 130062, China. Electronic address: renlz@jlu.edu.cn.

MeSH

Adenosine MonophosphateAlanineAmidesAntiviral AgentsBetacoronavirusCOVID-19ChinaCoronavirus InfectionsDrug CombinationsDrugs, Chinese HerbalHumansHydroxychloroquineIndolesInterferonsLopinavirPandemicsPneumonia, ViralPyrazinesRibavirinRitonavirSARS-CoV-2Survival AnalysisTeicoplanin

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

32592817

Citation

Li, Chang, et al. "Antiviral Mechanisms of Candidate Chemical Medicines and Traditional Chinese Medicines for SARS-CoV-2 Infection." Virus Research, vol. 286, 2020, p. 198073.
Li C, Wang L, Ren L. Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection. Virus Res. 2020;286:198073.
Li, C., Wang, L., & Ren, L. (2020). Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection. Virus Research, 286, 198073. https://doi.org/10.1016/j.virusres.2020.198073
Li C, Wang L, Ren L. Antiviral Mechanisms of Candidate Chemical Medicines and Traditional Chinese Medicines for SARS-CoV-2 Infection. Virus Res. 2020;286:198073. PubMed PMID: 32592817.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection. AU - Li,Chang, AU - Wang,Lin, AU - Ren,Linzhu, Y1 - 2020/06/24/ PY - 2020/05/02/received PY - 2020/06/22/revised PY - 2020/06/22/accepted PY - 2020/6/28/pubmed PY - 2020/9/9/medline PY - 2020/6/28/entrez KW - Antiviral KW - Coronavirus disease 2019 (COVID-19) KW - Medicine KW - Severe acute respiratory syndrome coronavirus 2 (2019 novel coronavirus, SARS-CoV-2) SP - 198073 EP - 198073 JF - Virus research JO - Virus Res VL - 286 N2 - The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global pandemic. Up to now, numerous medicines have been applied or approved for the prevention and control of the virus infection. However, the efficiency of each medicine or combination is completely different or still unknown. In this review, we discuss the types, characteristics, antiviral mechanisms, and shortcomings of recommended candidate medicines for SARS-CoV-2 infection, as well as perspectives of the drugs for the disease treatment, which may provide a theoretical basis for drug screening and application. SN - 1872-7492 UR - https://www.unboundmedicine.com/medline/citation/32592817/Antiviral_mechanisms_of_candidate_chemical_medicines_and_traditional_Chinese_medicines_for_SARS_CoV_2_infection_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0168-1702(20)30518-9 DB - PRIME DP - Unbound Medicine ER -