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Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration.
Neural Regen Res. 2020 Dec; 15(12):2207-2216.NR

Abstract

The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration. Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial growth factor compounds, among others, that prevent/diminish oxidative stress and reduce neovascularisation respectively. The phytochemicals, medicinal plants and/or plant-diet supplements might be a useful adjunct in prevention or treatment of age-related macular degeneration owing to their antioxidant and anti-vascular endothelial growth factor properties. This review article presents the most investigated plants and natural products in relation to age-related macular degeneration, such as saffron, ginkgo, bilberry and blueberry, curcuma or turmeric, carotenoids, polyphenols, and vitamins C and E. This study provides up-to-date information on the effects, treatments, safety and efficiency of these phytotherapy products.

Authors+Show Affiliations

Biomedical Sciences Institute; Department of Biomedical Sciences, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca, Valencia, Spain.Department of Pharmacy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca, Valencia, Spain.Department of Pharmacology, Pharmacognosy and Botany, Universidad Complutense de Madrid, Madrid, Spain.Department of Pharmaceutical and Health Sciences, Faculty of Pharmacy, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.Department of Chemistry and Biochemistry, Faculty of Pharmacy, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.Department of Pharmacy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca, Valencia, Spain.Department of Pharmacy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca, Valencia, Spain.Department of Pharmacy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca, Valencia, Spain.ICBiBE-Botanical Garden, University of Valencia, Valencia, Spain.Biomedical Sciences Institute; Department of Pharmacy, Faculty of Health Sciences, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca; ICBiBE-Botanical Garden, University of Valencia, Valencia, Spain.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

32594032

Citation

Bosch-Morell, Francisco, et al. "Medicinal Plants and Natural Products as Neuroprotective Agents in Age-related Macular Degeneration." Neural Regeneration Research, vol. 15, no. 12, 2020, pp. 2207-2216.
Bosch-Morell F, Villagrasa V, Ortega T, et al. Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration. Neural Regen Res. 2020;15(12):2207-2216.
Bosch-Morell, F., Villagrasa, V., Ortega, T., Acero, N., Muñoz-Mingarro, D., González-Rosende, M. E., Castillo, E., Sanahuja, M. A., Soriano, P., & Martínez-Solís, I. (2020). Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration. Neural Regeneration Research, 15(12), 2207-2216. https://doi.org/10.4103/1673-5374.284978
Bosch-Morell F, et al. Medicinal Plants and Natural Products as Neuroprotective Agents in Age-related Macular Degeneration. Neural Regen Res. 2020;15(12):2207-2216. PubMed PMID: 32594032.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration. AU - Bosch-Morell,Francisco, AU - Villagrasa,Victoria, AU - Ortega,Teresa, AU - Acero,Nuria, AU - Muñoz-Mingarro,Dolores, AU - González-Rosende,M Eugenia, AU - Castillo,Encarna, AU - Sanahuja,M Amparo, AU - Soriano,Pilar, AU - Martínez-Solís,Isabel, PY - 2020/6/29/entrez KW - age-related macular degeneration KW - bilberry KW - blueberry KW - carotenoids KW - curcuma KW - ginkgo KW - polyphenols KW - saffron KW - vitamins SP - 2207 EP - 2216 JF - Neural regeneration research JO - Neural Regen Res VL - 15 IS - 12 N2 - The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration. Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial growth factor compounds, among others, that prevent/diminish oxidative stress and reduce neovascularisation respectively. The phytochemicals, medicinal plants and/or plant-diet supplements might be a useful adjunct in prevention or treatment of age-related macular degeneration owing to their antioxidant and anti-vascular endothelial growth factor properties. This review article presents the most investigated plants and natural products in relation to age-related macular degeneration, such as saffron, ginkgo, bilberry and blueberry, curcuma or turmeric, carotenoids, polyphenols, and vitamins C and E. This study provides up-to-date information on the effects, treatments, safety and efficiency of these phytotherapy products. SN - 1673-5374 UR - https://www.unboundmedicine.com/medline/citation/32594032/Medicinal_plants_and_natural_products_as_neuroprotective_agents_in_age-related_macular_degeneration DB - PRIME DP - Unbound Medicine ER -
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