Tags

Type your tag names separated by a space and hit enter

HISTOPATHOLOGIC FINDINGS IN WOMEN UNDERGOING HYSTEROSCOPIC RESECTION OF ENDOMETRIAL POLYPS AND UTERINE MYOMAS.
Acta Clin Croat. 2019 Dec; 58(4):627-631.AC

Abstract

The aim of our study was to determine the prevalence of endometrial premalignant and malignant lesions in women undergoing hysteroscopy and to identify anthropologic factors related to the presence of malignancy. Data on 3470 women with submucosal myomas or endometrial polyps suspected on ultrasound were retrospectively analyzed. Hysteroscopy was performed in all these women in order to make a more precise diagnosis. Histologic analysis of endometrial samples obtained during hysteroscopy was used to confirm the diagnosis. Statistical analysis was performed using the SPSS 20.0.0 software. The mean age of study women was 49.1±13.3 years. The number of procedures performed due to the referral diagnosis of endometrial or submucosal myoma significantly increased over the 16-year study period. A significantly higher number of women had a benign histopathologic diagnosis. Histologic analysis revealed malignancy in 67 women. The youngest woman and oldest woman with malignant findings was aged 32 and 75, respectively. A significantly higher number of women with atypical hyperplasia and malignancy were in menopause. A comparable number of women with different histologic findings lived in urban and rural areas. There were a significantly larger proportion of widows among women with the histologic diagnosis of atypical hyperplasia or malignancy. The prevalence rate of malignancy in women having undergone hysteroscopy for polyps and myoma found by ultrasound was 1.93%. Postmenopausal status and older age were associated with an increased risk of malignancies, but premalignant changes and malignancies were also found in young and premenopausal women. Therefore, diagnostic hysteroscopy can be recommended in women of all age groups.

Authors+Show Affiliations

1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.1Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Medicine, University of Rijeka, Rijeka, Croatia; 3Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32595247

Citation

Soljačić Vraneš, Hrvojka, et al. "HISTOPATHOLOGIC FINDINGS in WOMEN UNDERGOING HYSTEROSCOPIC RESECTION of ENDOMETRIAL POLYPS and UTERINE MYOMAS." Acta Clinica Croatica, vol. 58, no. 4, 2019, pp. 627-631.
Soljačić Vraneš H, Djaković I, Vrljičak M, et al. HISTOPATHOLOGIC FINDINGS IN WOMEN UNDERGOING HYSTEROSCOPIC RESECTION OF ENDOMETRIAL POLYPS AND UTERINE MYOMAS. Acta Clin Croat. 2019;58(4):627-631.
Soljačić Vraneš, H., Djaković, I., Vrljičak, M., Đurić Orsag, N., Kuna, K., Kraljević, Z., Leniček, T., & Brlečić, I. (2019). HISTOPATHOLOGIC FINDINGS IN WOMEN UNDERGOING HYSTEROSCOPIC RESECTION OF ENDOMETRIAL POLYPS AND UTERINE MYOMAS. Acta Clinica Croatica, 58(4), 627-631. https://doi.org/10.20471/acc.2019.58.04.09
Soljačić Vraneš H, et al. HISTOPATHOLOGIC FINDINGS in WOMEN UNDERGOING HYSTEROSCOPIC RESECTION of ENDOMETRIAL POLYPS and UTERINE MYOMAS. Acta Clin Croat. 2019;58(4):627-631. PubMed PMID: 32595247.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - HISTOPATHOLOGIC FINDINGS IN WOMEN UNDERGOING HYSTEROSCOPIC RESECTION OF ENDOMETRIAL POLYPS AND UTERINE MYOMAS. AU - Soljačić Vraneš,Hrvojka, AU - Djaković,Ivka, AU - Vrljičak,Marija, AU - Đurić Orsag,Nives, AU - Kuna,Krunoslav, AU - Kraljević,Zdenko, AU - Leniček,Tanja, AU - Brlečić,Ivan, PY - 2020/6/30/entrez PY - 2020/7/1/pubmed PY - 2020/7/21/medline KW - Female KW - Hysteroscopy KW - Myoma KW - Polyps KW - Ultrasonography KW - Uterine neoplasms SP - 627 EP - 631 JF - Acta clinica Croatica JO - Acta Clin Croat VL - 58 IS - 4 N2 - The aim of our study was to determine the prevalence of endometrial premalignant and malignant lesions in women undergoing hysteroscopy and to identify anthropologic factors related to the presence of malignancy. Data on 3470 women with submucosal myomas or endometrial polyps suspected on ultrasound were retrospectively analyzed. Hysteroscopy was performed in all these women in order to make a more precise diagnosis. Histologic analysis of endometrial samples obtained during hysteroscopy was used to confirm the diagnosis. Statistical analysis was performed using the SPSS 20.0.0 software. The mean age of study women was 49.1±13.3 years. The number of procedures performed due to the referral diagnosis of endometrial or submucosal myoma significantly increased over the 16-year study period. A significantly higher number of women had a benign histopathologic diagnosis. Histologic analysis revealed malignancy in 67 women. The youngest woman and oldest woman with malignant findings was aged 32 and 75, respectively. A significantly higher number of women with atypical hyperplasia and malignancy were in menopause. A comparable number of women with different histologic findings lived in urban and rural areas. There were a significantly larger proportion of widows among women with the histologic diagnosis of atypical hyperplasia or malignancy. The prevalence rate of malignancy in women having undergone hysteroscopy for polyps and myoma found by ultrasound was 1.93%. Postmenopausal status and older age were associated with an increased risk of malignancies, but premalignant changes and malignancies were also found in young and premenopausal women. Therefore, diagnostic hysteroscopy can be recommended in women of all age groups. SN - 1333-9451 UR - https://www.unboundmedicine.com/medline/citation/32595247/HISTOPATHOLOGIC_FINDINGS_IN_WOMEN_UNDERGOING_HYSTEROSCOPIC_RESECTION_OF_ENDOMETRIAL_POLYPS_AND_UTERINE_MYOMAS L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/32595247/ DB - PRIME DP - Unbound Medicine ER -