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Replication of left ventricular haemodynamics with a simple planar mitral valve model.
Biomed Tech (Berl). 2020 Jun 29 [Online ahead of print]BT

Abstract

Tools for the numerical prediction of haemodynamics in multi-disciplinary integrated heart simulations have to be based on computational models that can be solved with low computational effort and still provide physiological flow characteristics. In this context the mitral valve model is important since it strongly influences the flow kinematics, especially during the diastolic phase. In contrast to a 3D valve, a vastly simplified valve model in form of a simple diode is known to be unable to reproduce the characteristic vortex formation and unable to promote a proper ventricular washout. In the present study, an adaptation of the widely used simplest modelling approach for the mitral valve is employed and compared to a physiologically inspired 3D valve within the same ventricular geometry. The adapted approach shows enhanced vortex formation and an improved ventricular washout in comparison to the diode type model. It further shows a high potential in reproducing the main flow characteristics and related particle residence times generated by a 3D valve.

Authors+Show Affiliations

Institute of Fluid Mechanics, Karlsruhe Institute of Technology, Karlsruhe, Germany.Institute of Fluid Mechanics, Karlsruhe Institute of Technology, Karlsruhe, Germany.Institute of Fluid Mechanics, Karlsruhe Institute of Technology, Karlsruhe, Germany.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32598293

Citation

Daub, Anna, et al. "Replication of Left Ventricular Haemodynamics With a Simple Planar Mitral Valve Model." Biomedizinische Technik. Biomedical Engineering, 2020.
Daub A, Kriegseis J, Frohnapfel B. Replication of left ventricular haemodynamics with a simple planar mitral valve model. Biomed Tech (Berl). 2020.
Daub, A., Kriegseis, J., & Frohnapfel, B. (2020). Replication of left ventricular haemodynamics with a simple planar mitral valve model. Biomedizinische Technik. Biomedical Engineering. https://doi.org/10.1515/bmt-2019-0175
Daub A, Kriegseis J, Frohnapfel B. Replication of Left Ventricular Haemodynamics With a Simple Planar Mitral Valve Model. Biomed Tech (Berl). 2020 Jun 29; PubMed PMID: 32598293.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Replication of left ventricular haemodynamics with a simple planar mitral valve model. AU - Daub,Anna, AU - Kriegseis,Jochen, AU - Frohnapfel,Bettina, Y1 - 2020/06/29/ PY - 2019/07/12/received PY - 2020/01/10/accepted PY - 2020/6/30/entrez KW - CFD KW - mitral valve KW - vortex identification JF - Biomedizinische Technik. Biomedical engineering JO - Biomed Tech (Berl) N2 - Tools for the numerical prediction of haemodynamics in multi-disciplinary integrated heart simulations have to be based on computational models that can be solved with low computational effort and still provide physiological flow characteristics. In this context the mitral valve model is important since it strongly influences the flow kinematics, especially during the diastolic phase. In contrast to a 3D valve, a vastly simplified valve model in form of a simple diode is known to be unable to reproduce the characteristic vortex formation and unable to promote a proper ventricular washout. In the present study, an adaptation of the widely used simplest modelling approach for the mitral valve is employed and compared to a physiologically inspired 3D valve within the same ventricular geometry. The adapted approach shows enhanced vortex formation and an improved ventricular washout in comparison to the diode type model. It further shows a high potential in reproducing the main flow characteristics and related particle residence times generated by a 3D valve. SN - 1862-278X UR - https://www.unboundmedicine.com/medline/citation/32598293/Replication_of_left_ventricular_haemodynamics_with_a_simple_planar_mitral_valve_model L2 - https://www.degruyter.com/doi/10.1515/bmt-2019-0175 DB - PRIME DP - Unbound Medicine ER -
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