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Gastric Inflammatory Fibroid Polyp: A Rare Cause of Occult Upper Gastrointestinal Bleeding.
J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709620936840.JI

Abstract

Inflammatory fibroid polyps (IFPs) are rare mesenchymal lesions that can arise throughout the gastrointestinal tract. These tumors represent less than 0.1% of all gastric polypoid lesions and are frequently found incidentally on endoscopic evaluation. While presenting symptoms depend on the location of the tumor, gastric polyps commonly present with epigastric pain and early satiety. We hereby delineate the case of a middle-aged female who presented with chronic iron deficiency anemia and a positive fecal occult blood test. She underwent an upper endoscopy, which revealed an actively oozing umbilicated lesion in the gastric antrum. Endoscopic ultrasound divulged the submucosal origin of the lesion. It was subsequently excised using endoscopic mucosal resection. Pathologic examination of the resected specimen confirmed the diagnosis of gastric IFP. Furthermore, we conducted a systematic literature search of the MEDLINE database centered on gastric IFPs from January 2000 till March 2020. The data on patient demographics, clinical features, endoscopic findings, lesion site and size, and treatment approaches were collected and analyzed. This article illustrates the overarching need for clinicians to be vigilant of gastric IFPs presenting with initial clinical symptoms suggestive of occult upper gastrointestinal bleeding. Prompt diagnosis and management of gastric IFPs carry paramount importance to combat chronic unexplained iron deficiency anemia following occult bleeding in such patients. A concoction of endoscopy, biopsy, and immunohistochemical examination can be employed toward their prompt detection. Although gastric IFPs have conventionally been treated with surgery, endoscopic resection is now emerging as a safe and efficient therapeutic modality.

Authors+Show Affiliations

Allama Iqbal Medical College, Lahore, Pakistan.Cleveland Clinic Florida, Weston, FL, USA.Baptist Medical Center South, Montgomery, AL, USA.Cleveland Clinic Florida, Weston, FL, USA.Services Institute of Medical Sciences, Lahore, Pakistan.Cleveland Clinic Florida, Weston, FL, USA.Cleveland Clinic Florida, Weston, FL, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32602395

Citation

Inayat, Faisal, et al. "Gastric Inflammatory Fibroid Polyp: a Rare Cause of Occult Upper Gastrointestinal Bleeding." Journal of Investigative Medicine High Impact Case Reports, vol. 8, 2020, p. 2324709620936840.
Inayat F, Ur Rahman A, Wahab A, et al. Gastric Inflammatory Fibroid Polyp: A Rare Cause of Occult Upper Gastrointestinal Bleeding. J Investig Med High Impact Case Rep. 2020;8:2324709620936840.
Inayat, F., Ur Rahman, A., Wahab, A., Riaz, A., Zahid, E., Bejarano, P., & Pimentel, R. (2020). Gastric Inflammatory Fibroid Polyp: A Rare Cause of Occult Upper Gastrointestinal Bleeding. Journal of Investigative Medicine High Impact Case Reports, 8, 2324709620936840. https://doi.org/10.1177/2324709620936840
Inayat F, et al. Gastric Inflammatory Fibroid Polyp: a Rare Cause of Occult Upper Gastrointestinal Bleeding. J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620936840. PubMed PMID: 32602395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastric Inflammatory Fibroid Polyp: A Rare Cause of Occult Upper Gastrointestinal Bleeding. AU - Inayat,Faisal, AU - Ur Rahman,Asad, AU - Wahab,Ahsan, AU - Riaz,Amir, AU - Zahid,Effa, AU - Bejarano,Pablo, AU - Pimentel,Ronnie, PY - 2020/7/1/entrez PY - 2020/7/1/pubmed PY - 2020/7/1/medline KW - Vanek’s tumor KW - gastric polyp KW - inflammatory fibroid polyp KW - iron deficiency anemia KW - occult upper gastrointestinal bleeding KW - stomach KW - upper endoscopy SP - 2324709620936840 EP - 2324709620936840 JF - Journal of investigative medicine high impact case reports JO - J Investig Med High Impact Case Rep VL - 8 N2 - Inflammatory fibroid polyps (IFPs) are rare mesenchymal lesions that can arise throughout the gastrointestinal tract. These tumors represent less than 0.1% of all gastric polypoid lesions and are frequently found incidentally on endoscopic evaluation. While presenting symptoms depend on the location of the tumor, gastric polyps commonly present with epigastric pain and early satiety. We hereby delineate the case of a middle-aged female who presented with chronic iron deficiency anemia and a positive fecal occult blood test. She underwent an upper endoscopy, which revealed an actively oozing umbilicated lesion in the gastric antrum. Endoscopic ultrasound divulged the submucosal origin of the lesion. It was subsequently excised using endoscopic mucosal resection. Pathologic examination of the resected specimen confirmed the diagnosis of gastric IFP. Furthermore, we conducted a systematic literature search of the MEDLINE database centered on gastric IFPs from January 2000 till March 2020. The data on patient demographics, clinical features, endoscopic findings, lesion site and size, and treatment approaches were collected and analyzed. This article illustrates the overarching need for clinicians to be vigilant of gastric IFPs presenting with initial clinical symptoms suggestive of occult upper gastrointestinal bleeding. Prompt diagnosis and management of gastric IFPs carry paramount importance to combat chronic unexplained iron deficiency anemia following occult bleeding in such patients. A concoction of endoscopy, biopsy, and immunohistochemical examination can be employed toward their prompt detection. Although gastric IFPs have conventionally been treated with surgery, endoscopic resection is now emerging as a safe and efficient therapeutic modality. SN - 2324-7096 UR - https://www.unboundmedicine.com/medline/citation/32602395/Gastric_Inflammatory_Fibroid_Polyp:_A_Rare_Cause_of_Occult_Upper_Gastrointestinal_Bleeding L2 - https://journals.sagepub.com/doi/10.1177/2324709620936840?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -
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