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Oral Anticoagulants - Utilisation and Expenditure under the Community Drugs Schemes.
Ir Med J. 2020 May 07; 113(5):71.IM

Abstract

Aims This study determined the impact of the direct oral anticoagulants (DOACs) on the utilisation and expenditure on oral anticoagulants (OACs) in the Irish Community healthcare setting. We also investigated aspects of DOAC prescribing. Methods Using anonymised prescription data from the HSE pharmacy claims database we investigated anticoagulant prescribing over the study period (1/1/2014 - 31/12/2018). Results Some 74,748 patients were being treated with OACs by the year end 2018 an increase of 30,319 over 5 years. Warfarin prescribing fell from 32,751 patients in 2014 to 16,166 by the year end 2018. Apixaban is the most frequently prescribed OAC and annual expenditure on DOACs now exceeds € 51 million. Patients treated with DOACs are older than participants in the pivotal clinical trials and are frequently co-administered interacting drugs. Conclusion The introduction of DOACs has resulted in an overall increase in anticoagulant prescribing, a significant reduction in warfarin usage and a large increase in expenditure.

Authors+Show Affiliations

Department of Pharmacology & Therapeutics, Trinity College Dublin. Health Services Executive (HSE) Medicines Management Programme.Department of Pharmacology & Therapeutics, Trinity College Dublin. Health Services Executive (HSE) Medicines Management Programme.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32603567

Citation

Smith, A, and M Barry. "Oral Anticoagulants - Utilisation and Expenditure Under the Community Drugs Schemes." Irish Medical Journal, vol. 113, no. 5, 2020, p. 71.
Smith A, Barry M. Oral Anticoagulants - Utilisation and Expenditure under the Community Drugs Schemes. Ir Med J. 2020;113(5):71.
Smith, A., & Barry, M. (2020). Oral Anticoagulants - Utilisation and Expenditure under the Community Drugs Schemes. Irish Medical Journal, 113(5), 71.
Smith A, Barry M. Oral Anticoagulants - Utilisation and Expenditure Under the Community Drugs Schemes. Ir Med J. 2020 May 7;113(5):71. PubMed PMID: 32603567.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral Anticoagulants - Utilisation and Expenditure under the Community Drugs Schemes. AU - Smith,A, AU - Barry,M, Y1 - 2020/05/07/ PY - 2020/7/1/entrez PY - 2020/7/1/pubmed PY - 2020/7/1/medline SP - 71 EP - 71 JF - Irish medical journal JO - Ir Med J VL - 113 IS - 5 N2 - Aims This study determined the impact of the direct oral anticoagulants (DOACs) on the utilisation and expenditure on oral anticoagulants (OACs) in the Irish Community healthcare setting. We also investigated aspects of DOAC prescribing. Methods Using anonymised prescription data from the HSE pharmacy claims database we investigated anticoagulant prescribing over the study period (1/1/2014 - 31/12/2018). Results Some 74,748 patients were being treated with OACs by the year end 2018 an increase of 30,319 over 5 years. Warfarin prescribing fell from 32,751 patients in 2014 to 16,166 by the year end 2018. Apixaban is the most frequently prescribed OAC and annual expenditure on DOACs now exceeds € 51 million. Patients treated with DOACs are older than participants in the pivotal clinical trials and are frequently co-administered interacting drugs. Conclusion The introduction of DOACs has resulted in an overall increase in anticoagulant prescribing, a significant reduction in warfarin usage and a large increase in expenditure. SN - 0332-3102 UR - https://www.unboundmedicine.com/medline/citation/32603567/Oral_Anticoagulants_-_Utilisation_and_Expenditure_under_the_Community_Drugs_Schemes DB - PRIME DP - Unbound Medicine ER -
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