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Necrobiosis Lipoidica in a Patient with β-Thalassemia Major: A Case Report and Review of the Literature.
Hemoglobin. 2020 May; 44(3):221-223.H

Abstract

Necrobiosis lipoidica (NL) is a rare granulomatous disease that predominantly affects middle-aged women and is often associated with diabetes mellitus (DM), rheumatoid arthritis (RA) and other metabolic disorders. Thalassemias are the most common hereditary hemoglobin (Hb) disorders worldwide. A few studies investigated dermatologic problems that coexist with β-thalassemia major (β-TM). The most common skin disorders in patients with β-TM are xerosis, urticaria, pseudoxanthoma, hyperpigmentation, leg ulcers and small-vessel vasculitis. Necrobiosis lipoidica has only been occasionally reported in patients with β-TM. Herein, we present a female with β-TM and NL. Furthermore, a brief review of the literature was performed.

Authors+Show Affiliations

Diabetes and Endocrine Department, South Warwickshire National Health Service Foundation Trust, Warwick, Warwickshire, UK.Second Propedeutical Department of Surgery, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.Department of Pathology, Hippokration Hospital, Thessaloniki, Greece.Adult Thalassemia Unit, Second Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.Fourth Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.Public Health and Social Care, Kavala, Greece.Second Propedeutical Department of Surgery, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.Adult Thalassemia Unit, Second Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

32605400

Citation

Vetsiou, Evangelia, et al. "Necrobiosis Lipoidica in a Patient With β-Thalassemia Major: a Case Report and Review of the Literature." Hemoglobin, vol. 44, no. 3, 2020, pp. 221-223.
Vetsiou E, Mpouras V, Nikolaidou C, et al. Necrobiosis Lipoidica in a Patient with β-Thalassemia Major: A Case Report and Review of the Literature. Hemoglobin. 2020;44(3):221-223.
Vetsiou, E., Mpouras, V., Nikolaidou, C., Klonizakis, P., Mandala, E., Vamvakis, K., Psarras, K., & Vlachaki, E. (2020). Necrobiosis Lipoidica in a Patient with β-Thalassemia Major: A Case Report and Review of the Literature. Hemoglobin, 44(3), 221-223. https://doi.org/10.1080/03630269.2020.1783287
Vetsiou E, et al. Necrobiosis Lipoidica in a Patient With β-Thalassemia Major: a Case Report and Review of the Literature. Hemoglobin. 2020;44(3):221-223. PubMed PMID: 32605400.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Necrobiosis Lipoidica in a Patient with β-Thalassemia Major: A Case Report and Review of the Literature. AU - Vetsiou,Evangelia, AU - Mpouras,Vasileios, AU - Nikolaidou,Christina, AU - Klonizakis,Philippos, AU - Mandala,Evdokia, AU - Vamvakis,Kyriakos, AU - Psarras,Kyriakos, AU - Vlachaki,Efthymia, Y1 - 2020/07/01/ PY - 2020/7/2/pubmed PY - 2020/7/2/medline PY - 2020/7/2/entrez KW - ferritin KW - necrobiosis lipoidica (NL) KW - reactive oxygen species (ROS) KW - β-Thalassemia major (β-TM) SP - 221 EP - 223 JF - Hemoglobin JO - Hemoglobin VL - 44 IS - 3 N2 - Necrobiosis lipoidica (NL) is a rare granulomatous disease that predominantly affects middle-aged women and is often associated with diabetes mellitus (DM), rheumatoid arthritis (RA) and other metabolic disorders. Thalassemias are the most common hereditary hemoglobin (Hb) disorders worldwide. A few studies investigated dermatologic problems that coexist with β-thalassemia major (β-TM). The most common skin disorders in patients with β-TM are xerosis, urticaria, pseudoxanthoma, hyperpigmentation, leg ulcers and small-vessel vasculitis. Necrobiosis lipoidica has only been occasionally reported in patients with β-TM. Herein, we present a female with β-TM and NL. Furthermore, a brief review of the literature was performed. SN - 1532-432X UR - https://www.unboundmedicine.com/medline/citation/32605400/Necrobiosis_Lipoidica_in_a_Patient_with_β-Thalassemia_Major:_A_Case_Report_and_Review_of_the_Literature L2 - http://www.tandfonline.com/doi/full/10.1080/03630269.2020.1783287 DB - PRIME DP - Unbound Medicine ER -
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