Vitamin B6 Fuels Acute Myeloid Leukemia Growth.Trends Cancer. 2020 Jul; 6(7):536-537.TC
Mounting evidence indicates that vitamins C and D are linked to tumor growth, but the relevance of vitamin B6 remains uncertain. In a recent study, Chen et al. demonstrate that pyridoxal kinase promotes vitamin B6 phosphorylation, producing the active form pyridoxal 5'-phosphate, which regulates two key metabolic enzymes required for acute myeloid leukemia (AML) cell growth.