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Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion) in Pediatric Phalanges.
J Hand Surg Am. 2020 Jun 28 [Online ahead of print]JH

Abstract

Bizarre parosteal osteochondromatous proliferation, or Nora tumor, is an uncommon lesion affecting the tubular bones of the hands and feet. Normally arising from the cortical surface and periosteum of these bones, these lesions histologically consist of a hypercellular cartilaginous cap covering a bony stalk that is surrounded by ossified areas and spindle cell stroma. The differential diagnosis includes conditions involving the periosteum such as chondrosarcoma, parosteal osteosarcoma, osteochondroma, turret exostosis, and florid reactive periostitis. The only effective treatment is wide surgical excision; nevertheless, local recurrence rates are extremely high and may necessitate revision surgery. In the present study, we report 3 cases of Nora lesion located in the hand in pediatric patients. The diagnosis in these cases was challenging owing to their presenting symptoms and radiographic findings. The diagnosis was made based on characteristic findings noted on the radiographic images and was confirmed by histological examination following excision.

Authors+Show Affiliations

Cirugía Ortopédica y Traumatología, Hospital Universitario Infantil Niño Jesús, Madrid, Spain.Departamento de Patología, Hospital Universitario Infantil Niño Jesús, Madrid, Spain.Associate Professor for Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH; Cirugía Ortopédica y Traumatología, Hospital Universitario Infantil Niño Jesús, Madrid, Spain. Electronic address: Kevin.little@cchmc.org.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

32611484

Citation

Martínez Álvarez, Sergio, et al. "Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion) in Pediatric Phalanges." The Journal of Hand Surgery, 2020.
Martínez Álvarez S, Azorín Cuadrillero DL, Little KJ. Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion) in Pediatric Phalanges. J Hand Surg Am. 2020.
Martínez Álvarez, S., Azorín Cuadrillero, D. L., & Little, K. J. (2020). Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion) in Pediatric Phalanges. The Journal of Hand Surgery. https://doi.org/10.1016/j.jhsa.2020.05.002
Martínez Álvarez S, Azorín Cuadrillero DL, Little KJ. Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion) in Pediatric Phalanges. J Hand Surg Am. 2020 Jun 28; PubMed PMID: 32611484.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion) in Pediatric Phalanges. AU - Martínez Álvarez,Sergio, AU - Azorín Cuadrillero,Daniel L, AU - Little,Kevin J, Y1 - 2020/06/28/ PY - 2019/08/26/received PY - 2020/04/05/revised PY - 2020/05/12/accepted PY - 2020/7/3/entrez KW - BPOP KW - Nora lesion KW - bizarre parosteal osteochondromatous proliferation KW - hand tumor KW - pediatric JF - The Journal of hand surgery JO - J Hand Surg Am N2 - Bizarre parosteal osteochondromatous proliferation, or Nora tumor, is an uncommon lesion affecting the tubular bones of the hands and feet. Normally arising from the cortical surface and periosteum of these bones, these lesions histologically consist of a hypercellular cartilaginous cap covering a bony stalk that is surrounded by ossified areas and spindle cell stroma. The differential diagnosis includes conditions involving the periosteum such as chondrosarcoma, parosteal osteosarcoma, osteochondroma, turret exostosis, and florid reactive periostitis. The only effective treatment is wide surgical excision; nevertheless, local recurrence rates are extremely high and may necessitate revision surgery. In the present study, we report 3 cases of Nora lesion located in the hand in pediatric patients. The diagnosis in these cases was challenging owing to their presenting symptoms and radiographic findings. The diagnosis was made based on characteristic findings noted on the radiographic images and was confirmed by histological examination following excision. SN - 1531-6564 UR - https://www.unboundmedicine.com/medline/citation/32611484/Bizarre_Parosteal_Osteochondromatous_Proliferation_(Nora_Lesion)_in_Pediatric_Phalanges L2 - https://linkinghub.elsevier.com/retrieve/pii/S0363-5023(20)30269-0 DB - PRIME DP - Unbound Medicine ER -
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